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Journal Abstract Search

446 related items for PubMed ID: 15173588

  • 1. Down-regulation of Smad7 expression by ubiquitin-dependent degradation contributes to renal fibrosis in obstructive nephropathy in mice.
    Fukasawa H, Yamamoto T, Togawa A, Ohashi N, Fujigaki Y, Oda T, Uchida C, Kitagawa K, Hattori T, Suzuki S, Kitagawa M, Hishida A.
    Proc Natl Acad Sci U S A; 2004 Jun 08; 101(23):8687-92. PubMed ID: 15173588
    [Abstract] [Full Text] [Related]

  • 2. NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.
    Kuratomi G, Komuro A, Goto K, Shinozaki M, Miyazawa K, Miyazono K, Imamura T.
    Biochem J; 2005 Mar 15; 386(Pt 3):461-70. PubMed ID: 15496141
    [Abstract] [Full Text] [Related]

  • 3. Arkadia-Smad7-mediated positive regulation of TGF-beta signaling in a rat model of tubulointerstitial fibrosis.
    Liu FY, Li XZ, Peng YM, Liu H, Liu YH.
    Am J Nephrol; 2007 Mar 15; 27(2):176-83. PubMed ID: 17347560
    [Abstract] [Full Text] [Related]

  • 4. Ubiquitin-dependent degradation of SnoN and Ski is increased in renal fibrosis induced by obstructive injury.
    Fukasawa H, Yamamoto T, Togawa A, Ohashi N, Fujigaki Y, Oda T, Uchida C, Kitagawa K, Hattori T, Suzuki S, Kitagawa M, Hishida A.
    Kidney Int; 2006 May 15; 69(10):1733-40. PubMed ID: 16625151
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model.
    Lan HY, Mu W, Tomita N, Huang XR, Li JH, Zhu HJ, Morishita R, Johnson RJ.
    J Am Soc Nephrol; 2003 Jun 15; 14(6):1535-48. PubMed ID: 12761254
    [Abstract] [Full Text] [Related]

  • 6. Loss of angiotensin-converting enzyme 2 enhances TGF-β/Smad-mediated renal fibrosis and NF-κB-driven renal inflammation in a mouse model of obstructive nephropathy.
    Liu Z, Huang XR, Chen HY, Penninger JM, Lan HY.
    Lab Invest; 2012 May 15; 92(5):650-61. PubMed ID: 22330342
    [Abstract] [Full Text] [Related]

  • 7. Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction.
    Sato M, Muragaki Y, Saika S, Roberts AB, Ooshima A.
    J Clin Invest; 2003 Nov 15; 112(10):1486-94. PubMed ID: 14617750
    [Abstract] [Full Text] [Related]

  • 8. Downregulation of SnoN expression in obstructive nephropathy is mediated by an enhanced ubiquitin-dependent degradation.
    Tan R, Zhang J, Tan X, Zhang X, Yang J, Liu Y.
    J Am Soc Nephrol; 2006 Oct 15; 17(10):2781-91. PubMed ID: 16959829
    [Abstract] [Full Text] [Related]

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  • 10. HUWE1 promotes EGFR ubiquitination and degradation to protect against renal tubulointerstitial fibrosis.
    Zhu Q, Dong H, Bukhari AA, Zhao A, Li M, Sun Y, Zhang X, Cao C, Su D, Liang X.
    FASEB J; 2020 Mar 15; 34(3):4591-4601. PubMed ID: 32017279
    [Abstract] [Full Text] [Related]

  • 11. Astragaloside IV inhibits renal tubulointerstitial fibrosis by blocking TGF-β/Smad signaling pathway in vivo and in vitro.
    Wang L, Chi YF, Yuan ZT, Zhou WC, Yin PH, Zhang XM, Peng W, Cai H.
    Exp Biol Med (Maywood); 2014 Oct 15; 239(10):1310-24. PubMed ID: 24879422
    [Abstract] [Full Text] [Related]

  • 12. Bardoxolone ameliorates TGF-β1-associated renal fibrosis through Nrf2/Smad7 elevation.
    Song MK, Lee JH, Ryoo IG, Lee SH, Ku SK, Kwak MK.
    Free Radic Biol Med; 2019 Jul 15; 138():33-42. PubMed ID: 31059771
    [Abstract] [Full Text] [Related]

  • 13. Deficient Smad7 expression: a putative molecular defect in scleroderma.
    Dong C, Zhu S, Wang T, Yoon W, Li Z, Alvarez RJ, ten Dijke P, White B, Wigley FM, Goldschmidt-Clermont PJ.
    Proc Natl Acad Sci U S A; 2002 Mar 19; 99(6):3908-13. PubMed ID: 11904440
    [Abstract] [Full Text] [Related]

  • 14. [Effects of Chinese herbal medicine Yiqi Huoxue Formula on TGF-β/smad signal transduction pathway and connective tissue growth factor in rats with renal interstitial fibrosis].
    Liu YM, Liu RH, Liu WJ, Liu L, Wu ZK, Chen YY.
    Zhong Xi Yi Jie He Xue Bao; 2010 Dec 19; 8(12):1165-73. PubMed ID: 21144460
    [Abstract] [Full Text] [Related]

  • 15. Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases.
    Morén A, Imamura T, Miyazono K, Heldin CH, Moustakas A.
    J Biol Chem; 2005 Jun 10; 280(23):22115-23. PubMed ID: 15817471
    [Abstract] [Full Text] [Related]

  • 16. HuangQi Decoction Ameliorates Renal Fibrosis via TGF-β/Smad Signaling Pathway In Vivo and In Vitro.
    Zhao J, Wang L, Cao AL, Jiang MQ, Chen X, Wang Y, Wang YM, Wang H, Zhang XM, Peng W.
    Cell Physiol Biochem; 2016 Jun 10; 38(5):1761-74. PubMed ID: 27161221
    [Abstract] [Full Text] [Related]

  • 17. Smad3 deficiency attenuates renal fibrosis, inflammation,and apoptosis after unilateral ureteral obstruction.
    Inazaki K, Kanamaru Y, Kojima Y, Sueyoshi N, Okumura K, Kaneko K, Yamashiro Y, Ogawa H, Nakao A.
    Kidney Int; 2004 Aug 10; 66(2):597-604. PubMed ID: 15253712
    [Abstract] [Full Text] [Related]

  • 18. Vitamin E ameliorates renal fibrosis by inhibition of TGF-beta/Smad2/3 signaling pathway in UUO mice.
    Tasanarong A, Kongkham S, Duangchana S, Thitiarchakul S, Eiam-Ong S.
    J Med Assoc Thai; 2011 Dec 10; 94 Suppl 7():S1-9. PubMed ID: 22619900
    [Abstract] [Full Text] [Related]

  • 19. Transforming growth factor-beta and Smad signalling in kidney diseases.
    Wang W, Koka V, Lan HY.
    Nephrology (Carlton); 2005 Feb 10; 10(1):48-56. PubMed ID: 15705182
    [Abstract] [Full Text] [Related]

  • 20. Ubiquitination and regulation of Smad7 in the TGF-β1/Smad signaling of aristolochic acid nephropathy.
    Tian Y, Liao F, Wu G, Chang D, Yang Y, Dong X, Zhang Z, Zhang Y, Wu G.
    Toxicol Mech Methods; 2015 Feb 10; 25(8):645-52. PubMed ID: 26108275
    [Abstract] [Full Text] [Related]

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