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260 related items for PubMed ID: 15177438

  • 1. 6-Arylamino-7-chloro-quinazoline-5,8-diones as novel cytotoxic and DNA topoisomerase inhibitory agents.
    Park HJ, Kim YS, Kim JS, Lee EJ, Yi YJ, Hwang HJ, Suh ME, Ryu CK, Lee SK.
    Bioorg Med Chem Lett; 2004 Jul 05; 14(13):3385-8. PubMed ID: 15177438
    [Abstract] [Full Text] [Related]

  • 2. Synthesis of 6-chloroisoquinoline-5,8-diones and pyrido[3,4-b]phenazine-5,12-diones and evaluation of their cytotoxicity and DNA topoisomerase II inhibitory activity.
    Kim JS, Rhee HK, Park HJ, Lee IK, Lee SK, Suh ME, Lee HJ, Ryu CK, Choo HY.
    Bioorg Med Chem; 2007 Jan 01; 15(1):451-7. PubMed ID: 17035025
    [Abstract] [Full Text] [Related]

  • 3. Cytotoxicity and DNA topoisomerase inhibitory activity of benz[f]indole-4,9-dione analogs.
    Park HJ, Lee HJ, Lee EJ, Hwang HJ, Shin SH, Suh ME, Kim C, Kim HJ, Seo EK, Lee SK.
    Biosci Biotechnol Biochem; 2003 Sep 01; 67(9):1944-9. PubMed ID: 14519980
    [Abstract] [Full Text] [Related]

  • 4. 2,4,6-Trisubstituted pyridines: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship.
    Basnet A, Thapa P, Karki R, Na Y, Jahng Y, Jeong BS, Jeong TC, Lee CS, Lee ES.
    Bioorg Med Chem; 2007 Jul 01; 15(13):4351-9. PubMed ID: 17493824
    [Abstract] [Full Text] [Related]

  • 5. 2,3-Disubstituted 8-arylamino-3H-imidazo[4,5-g]quinazolines: a novel class of antitumor agents.
    Zhang Y, Chen Z, Lou Y, Yu Y.
    Eur J Med Chem; 2009 Jan 01; 44(1):448-52. PubMed ID: 18313807
    [Abstract] [Full Text] [Related]

  • 6. Design, docking, and synthesis of novel indeno[1,2-c]isoquinolines for the development of antitumor agents as topoisomerase I inhibitors.
    Cho WJ, Le QM, My Van HT, Youl Lee K, Kang BY, Lee ES, Lee SK, Kwon Y.
    Bioorg Med Chem Lett; 2007 Jul 01; 17(13):3531-4. PubMed ID: 17498951
    [Abstract] [Full Text] [Related]

  • 7. Synthesis of nitrated indenoisoquinolines as topoisomerase I inhibitors.
    Morrell A, Antony S, Kohlhagen G, Pommier Y, Cushman M.
    Bioorg Med Chem Lett; 2004 Jul 16; 14(14):3659-63. PubMed ID: 15203138
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and cytotoxic activity of a new series of topoisomerase I inhibitors.
    Dallavalle S, Gattinoni S, Mazzini S, Scaglioni L, Merlini L, Tinelli S, Beretta GL, Zunino F.
    Bioorg Med Chem Lett; 2008 Feb 15; 18(4):1484-9. PubMed ID: 18248813
    [Abstract] [Full Text] [Related]

  • 9. Substitution at the F-ring N-imide of the indolocarbazole antitumor drug NB-506 increases the cytotoxicity, DNA binding, and topoisomerase I inhibition activities.
    Bailly C, Qu X, Chaires JB, Colson P, Houssier C, Ohkubo M, Nishimura S, Yoshinari T.
    J Med Chem; 1999 Jul 29; 42(15):2927-35. PubMed ID: 10425102
    [Abstract] [Full Text] [Related]

  • 10. Design of new topoisomerase II inhibitors based upon a quinobenzoxazine self-assembly model.
    Zeng Q, Kwok Y, Kerwin SM, Mangold G, Hurley LH.
    J Med Chem; 1998 Oct 22; 41(22):4273-8. PubMed ID: 9784102
    [Abstract] [Full Text] [Related]

  • 11. Design, synthesis, and evaluation of novel 6-chloro-/fluorochromone derivatives as potential topoisomerase inhibitor anticancer agents.
    Ishar MP, Singh G, Singh S, Sreenivasan KK, Singh G.
    Bioorg Med Chem Lett; 2006 Mar 01; 16(5):1366-70. PubMed ID: 16332438
    [Abstract] [Full Text] [Related]

  • 12. Antitumor agents. 194. Synthesis and biological evaluations of 4-beta-mono-, -di-, and -trisubstituted aniline-4'-O-demethyl-podophyllotoxin and related compounds with improved pharmacological profiles.
    Zhu XK, Guan J, Tachibana Y, Bastow KF, Cho SJ, Cheng HH, Cheng YC, Gurwith M, Lee KH.
    J Med Chem; 1999 Jul 01; 42(13):2441-6. PubMed ID: 10395485
    [Abstract] [Full Text] [Related]

  • 13. Synthesis of rotenoid derivatives with cytotoxic and topoisomerase II inhibitory activities.
    Sangthong S, Krusong K, Ngamrojanavanich N, Vilaivan T, Puthong S, Chandchawan S, Muangsin N.
    Bioorg Med Chem Lett; 2011 Aug 15; 21(16):4813-8. PubMed ID: 21741833
    [Abstract] [Full Text] [Related]

  • 14. New benzoxanthone derivatives as topoisomerase inhibitors and DNA cross-linkers.
    Cho HJ, Jung MJ, Woo S, Kim J, Lee ES, Kwon Y, Na Y.
    Bioorg Med Chem; 2010 Feb 15; 18(3):1010-7. PubMed ID: 20093033
    [Abstract] [Full Text] [Related]

  • 15. Novel tetra-acridine derivatives as dual inhibitors of topoisomerase II and the human proteasome.
    Vispé S, Vandenberghe I, Robin M, Annereau JP, Créancier L, Pique V, Galy JP, Kruczynski A, Barret JM, Bailly C.
    Biochem Pharmacol; 2007 Jun 15; 73(12):1863-72. PubMed ID: 17391647
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and antitumor activity of novel quinazoline derivatives containing thiosemicarbazide moiety.
    He J, Wang X, Zhao X, Liang Y, He H, Fu L.
    Eur J Med Chem; 2012 Aug 15; 54():925-30. PubMed ID: 22749192
    [Abstract] [Full Text] [Related]

  • 17. Antitumor agents. 185. Synthesis and biological evaluation of tridemethylthiocolchicine analogues as novel topoisomerase II inhibitors.
    Guan J, Zhu XK, Tachibana Y, Bastow KF, Brossi A, Hamel E, Lee KH.
    J Med Chem; 1998 May 21; 41(11):1956-61. PubMed ID: 9599244
    [Abstract] [Full Text] [Related]

  • 18. 2-Thienyl-4-furyl-6-aryl pyridine derivatives: synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study.
    Thapa P, Karki R, Thapa U, Jahng Y, Jung MJ, Nam JM, Na Y, Kwon Y, Lee ES.
    Bioorg Med Chem; 2010 Jan 01; 18(1):377-86. PubMed ID: 19939682
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and antitumor activity of the hexacyclic camptothecin derivatives.
    Gao H, Zhang X, Chen Y, Shen H, Pang T, Sun J, Xu C, Ding J, Li C, Lu W.
    Bioorg Med Chem Lett; 2005 Jul 01; 15(13):3233-6. PubMed ID: 15913996
    [Abstract] [Full Text] [Related]

  • 20. Oxiranylmethyloxy or thiiranylmethyloxy-azaxanthones and -acridone analogues as potential topoisomerase I inhibitors.
    Cho HJ, Jung MJ, Kwon Y, Na Y.
    Bioorg Med Chem Lett; 2009 Dec 01; 19(23):6766-9. PubMed ID: 19836231
    [Abstract] [Full Text] [Related]

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