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2. Reduced hippocampal insulin-degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-epsilon4 allele. Cook DG, Leverenz JB, McMillan PJ, Kulstad JJ, Ericksen S, Roth RA, Schellenberg GD, Jin LW, Kovacina KS, Craft S. Am J Pathol; 2003 Jan; 162(1):313-9. PubMed ID: 12507914 [Abstract] [Full Text] [Related]
3. Insulin degrading enzyme (IDE) genetic variants and risk of Alzheimer's disease: evidence of effect modification by apolipoprotein E (APOE). Edland SD, Wavrant-De Vriesé F, Compton D, Smith GE, Ivnik R, Boeve BF, Tangalos EG, Petersen RC. Neurosci Lett; 2003 Jul 10; 345(1):21-4. PubMed ID: 12809979 [Abstract] [Full Text] [Related]
4. Insulin-degrading enzyme and Alzheimer disease: a genetic association study in the Han Chinese. Bian L, Yang JD, Guo TW, Sun Y, Duan SW, Chen WY, Pan YX, Feng GY, He L. Neurology; 2004 Jul 27; 63(2):241-5. PubMed ID: 15277615 [Abstract] [Full Text] [Related]
5. Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: review and hypothesis. Qiu WQ, Folstein MF. Neurobiol Aging; 2006 Feb 27; 27(2):190-8. PubMed ID: 16399206 [Abstract] [Full Text] [Related]
6. Association of insulin degrading enzyme gene polymorphisms with Alzheimer's disease: a meta-analysis. Cheng H, Wang L, Shi T, Shang Y, Jiang L. Int J Neurosci; 2015 May 27; 125(5):328-35. PubMed ID: 25105907 [Abstract] [Full Text] [Related]
7. Combined risk effects of IDE and NEP gene variants on Alzheimer disease. Vepsäläinen S, Helisalmi S, Mannermaa A, Pirttilä T, Soininen H, Hiltunen M. J Neurol Neurosurg Psychiatry; 2009 Nov 27; 80(11):1268-70. PubMed ID: 19864659 [Abstract] [Full Text] [Related]
8. Cholesteryl ester transfer protein (CETP) polymorphism modifies the Alzheimer's disease risk associated with APOE epsilon4 allele. Rodríguez E, Mateo I, Infante J, Llorca J, Berciano J, Combarros O. J Neurol; 2006 Feb 27; 253(2):181-5. PubMed ID: 16096813 [Abstract] [Full Text] [Related]
9. Sequence variants of IDE are associated with the extent of beta-amyloid deposition in the Alzheimer's disease brain. Blomqvist ME, Chalmers K, Andreasen N, Bogdanovic N, Wilcock GK, Cairns NJ, Feuk L, Brookes AJ, Love S, Blennow K, Kehoe PG, Prince JA. Neurobiol Aging; 2005 Jun 27; 26(6):795-802. PubMed ID: 15718037 [Abstract] [Full Text] [Related]
10. Apolipoprotein E-epsilon4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease. Premkumar DR, Cohen DL, Hedera P, Friedland RP, Kalaria RN. Am J Pathol; 1996 Jun 27; 148(6):2083-95. PubMed ID: 8669492 [Abstract] [Full Text] [Related]
11. Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme. Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell T, Holmans P, Hamshere M, Turic D, Jehu L, Hollingworth P, Moore P, Bryden L, Myers A, Doil LM, Tacey KM, Gibson AM, McKeith IG, Perry RH, Morris CM, Thal L, Morris JC, O'Donovan MC, Lovestone S, Grupe A, Hardy J, Owen MJ, Williams J, Goate A. Am J Med Genet B Neuropsychiatr Genet; 2005 Jul 05; 136B(1):62-8. PubMed ID: 15858813 [Abstract] [Full Text] [Related]
13. Alternative splicing of human insulin-degrading enzyme yields a novel isoform with a decreased ability to degrade insulin and amyloid beta-protein. Farris W, Leissring MA, Hemming ML, Chang AY, Selkoe DJ. Biochemistry; 2005 May 03; 44(17):6513-25. PubMed ID: 15850385 [Abstract] [Full Text] [Related]
14. Characteristics of Insulin-degrading Enzyme in Alzheimer's Disease: A Meta-Analysis. Zhang H, Liu D, Huang H, Zhao Y, Zhou H. Curr Alzheimer Res; 2018 May 03; 15(7):610-617. PubMed ID: 29357797 [Abstract] [Full Text] [Related]
15. Insulin-degrading enzyme is genetically associated with Alzheimer's disease in the Finnish population. Vepsäläinen S, Parkinson M, Helisalmi S, Mannermaa A, Soininen H, Tanzi RE, Bertram L, Hiltunen M. J Med Genet; 2007 Sep 03; 44(9):606-8. PubMed ID: 17496198 [Abstract] [Full Text] [Related]
16. Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo. Farris W, Mansourian S, Chang Y, Lindsley L, Eckman EA, Frosch MP, Eckman CB, Tanzi RE, Selkoe DJ, Guenette S. Proc Natl Acad Sci U S A; 2003 Apr 01; 100(7):4162-7. PubMed ID: 12634421 [Abstract] [Full Text] [Related]
17. Evidence for genetic linkage of Alzheimer's disease to chromosome 10q. Bertram L, Blacker D, Mullin K, Keeney D, Jones J, Basu S, Yhu S, McInnis MG, Go RC, Vekrellis K, Selkoe DJ, Saunders AJ, Tanzi RE. Science; 2000 Dec 22; 290(5500):2302-3. PubMed ID: 11125142 [Abstract] [Full Text] [Related]
18. Apolipoprotein E genotype and the diagnostic accuracy of cerebrospinal fluid biomarkers for Alzheimer disease. Lautner R, Palmqvist S, Mattsson N, Andreasson U, Wallin A, Pålsson E, Jakobsson J, Herukka SK, Owenius R, Olsson B, Hampel H, Rujescu D, Ewers M, Landén M, Minthon L, Blennow K, Zetterberg H, Hansson O, Alzheimer’s Disease Neuroimaging Initiative. JAMA Psychiatry; 2014 Oct 22; 71(10):1183-91. PubMed ID: 25162367 [Abstract] [Full Text] [Related]
19. Positive association between risk for late-onset Alzheimer disease and genetic variation in IDE. Björk BF, Katzov H, Kehoe P, Fratiglioni L, Winblad B, Prince JA, Graff C. Neurobiol Aging; 2007 Sep 22; 28(9):1374-80. PubMed ID: 16876916 [Abstract] [Full Text] [Related]
20. Genetic variation in a haplotype block spanning IDE influences Alzheimer disease. Prince JA, Feuk L, Gu HF, Johansson B, Gatz M, Blennow K, Brookes AJ. Hum Mutat; 2003 Nov 22; 22(5):363-71. PubMed ID: 14517947 [Abstract] [Full Text] [Related] Page: [Next] [New Search]