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2. The acid-mediated denaturation pathway of transthyretin yields a conformational intermediate that can self-assemble into amyloid. Lai Z, Colón W, Kelly JW. Biochemistry; 1996 May 21; 35(20):6470-82. PubMed ID: 8639594 [Abstract] [Full Text] [Related]
5. Kinetic stabilization of an oligomeric protein under physiological conditions demonstrated by a lack of subunit exchange: implications for transthyretin amyloidosis. Wiseman RL, Green NS, Kelly JW. Biochemistry; 2005 Jun 28; 44(25):9265-74. PubMed ID: 15966751 [Abstract] [Full Text] [Related]
8. Synthesis and characterization of potent bivalent amyloidosis inhibitors that bind prior to transthyretin tetramerization. Green NS, Palaninathan SK, Sacchettini JC, Kelly JW. J Am Chem Soc; 2003 Nov 05; 125(44):13404-14. PubMed ID: 14583036 [Abstract] [Full Text] [Related]
11. The sequence-dependent unfolding pathway plays a critical role in the amyloidogenicity of transthyretin. Yang M, Yordanov B, Levy Y, Brüschweiler R, Huo S. Biochemistry; 2006 Oct 03; 45(39):11992-2002. PubMed ID: 17002298 [Abstract] [Full Text] [Related]
12. Intermolecular disulfide linkages are not required for transthyretin amyloid fibril formation in vitro. McCutchen SL, Kelly JW. Biochem Biophys Res Commun; 1993 Dec 15; 197(2):415-21. PubMed ID: 8267575 [Abstract] [Full Text] [Related]
13. Kinetic stabilization of an oligomeric protein by a single ligand binding event. Wiseman RL, Johnson SM, Kelker MS, Foss T, Wilson IA, Kelly JW. J Am Chem Soc; 2005 Apr 20; 127(15):5540-51. PubMed ID: 15826192 [Abstract] [Full Text] [Related]
15. Tetramer dissociation and monomer partial unfolding precedes protofibril formation in amyloidogenic transthyretin variants. Quintas A, Vaz DC, Cardoso I, Saraiva MJ, Brito RM. J Biol Chem; 2001 Jul 20; 276(29):27207-13. PubMed ID: 11306576 [Abstract] [Full Text] [Related]
16. Cys10 mixed disulfides make transthyretin more amyloidogenic under mildly acidic conditions. Zhang Q, Kelly JW. Biochemistry; 2003 Jul 29; 42(29):8756-61. PubMed ID: 12873136 [Abstract] [Full Text] [Related]
17. The pathway by which the tetrameric protein transthyretin dissociates. Foss TR, Wiseman RL, Kelly JW. Biochemistry; 2005 Nov 29; 44(47):15525-33. PubMed ID: 16300401 [Abstract] [Full Text] [Related]
20. Chromium(III) ion and thyroxine cooperate to stabilize the transthyretin tetramer and suppress in vitro amyloid fibril formation. Sato T, Ando Y, Susuki S, Mikami F, Ikemizu S, Nakamura M, Suhr O, Anraku M, Kai T, Suico MA, Shuto T, Mizuguchi M, Yamagata Y, Kai H. FEBS Lett; 2006 Jan 23; 580(2):491-6. PubMed ID: 16386248 [Abstract] [Full Text] [Related] Page: [Next] [New Search]