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328 related items for PubMed ID: 15182182

  • 1. Gln212, Asn270, and Arg301 are critical for catalysis by adenylosuccinate lyase from Bacillus subtilis.
    Segall ML, Colman RF.
    Biochemistry; 2004 Jun 15; 43(23):7391-402. PubMed ID: 15182182
    [Abstract] [Full Text] [Related]

  • 2. Characterization of a mutant Bacillus subtilis adenylosuccinate lyase equivalent to a mutant enzyme found in human adenylosuccinate lyase deficiency: asparagine 276 plays an important structural role.
    Palenchar JB, Colman RF.
    Biochemistry; 2003 Feb 25; 42(7):1831-41. PubMed ID: 12590570
    [Abstract] [Full Text] [Related]

  • 3. His68 and His141 are critical contributors to the intersubunit catalytic site of adenylosuccinate lyase of Bacillus subtilis.
    Lee TT, Worby C, Bao ZQ, Dixon JE, Colman RF.
    Biochemistry; 1999 Jan 05; 38(1):22-32. PubMed ID: 9890879
    [Abstract] [Full Text] [Related]

  • 4. Three subunits contribute amino acids to the active site of tetrameric adenylosuccinate lyase: Lys268 and Glu275 are required.
    Brosius JL, Colman RF.
    Biochemistry; 2002 Feb 19; 41(7):2217-26. PubMed ID: 11841213
    [Abstract] [Full Text] [Related]

  • 5. Implication of His68 in the substrate site of Bacillus subtilis adenylosuccinate lyase by mutagenesis and affinity labeling with 2-[(4-bromo-2,3-dioxobutyl)thio]adenosine 5'-monophosphate.
    Lee TT, Worby C, Bao ZQ, Dixon JE, Colman RF.
    Biochemistry; 1998 Jun 09; 37(23):8481-9. PubMed ID: 9622500
    [Abstract] [Full Text] [Related]

  • 6. Evaluation of types of interactions in subunit association in Bacillus subtilis adenylosuccinate lyase.
    De Zoysa Ariyananda L, Colman RF.
    Biochemistry; 2008 Mar 04; 47(9):2923-34. PubMed ID: 18237141
    [Abstract] [Full Text] [Related]

  • 7. The characterization of mutant Bacillus subtilis adenylosuccinate lyases corresponding to severe human adenylosuccinate lyase deficiencies.
    Palenchar JB, Crocco JM, Colman RF.
    Protein Sci; 2003 Aug 04; 12(8):1694-705. PubMed ID: 12876319
    [Abstract] [Full Text] [Related]

  • 8. A key role in catalysis for His89 of adenylosuccinate lyase of Bacillus subtilis.
    Brosius JL, Colman RF.
    Biochemistry; 2000 Nov 07; 39(44):13336-43. PubMed ID: 11063569
    [Abstract] [Full Text] [Related]

  • 9. Site-directed mutagenesis of the putative distal helix of peroxygenase cytochrome P450.
    Matsunaga I, Ueda A, Sumimoto T, Ichihara K, Ayata M, Ogura H.
    Arch Biochem Biophys; 2001 Oct 01; 394(1):45-53. PubMed ID: 11566026
    [Abstract] [Full Text] [Related]

  • 10. Affinity Labeling of the active site of rabbit muscle adenylosuccinate lyase by 2-[(4-bromo-2.3-dioxobutyl)thio] adenosine 5'-monophosphate.
    Gite SU, Colman RF.
    Biochemistry; 1996 Feb 27; 35(8):2658-67. PubMed ID: 8611571
    [Abstract] [Full Text] [Related]

  • 11. Effect of Asp69 and Arg310 on the pK of His68, a key catalytic residue of adenylosuccinate lyase.
    Sivendran S, Segall ML, Rancy PC, Colman RF.
    Protein Sci; 2007 Aug 27; 16(8):1700-7. PubMed ID: 17600142
    [Abstract] [Full Text] [Related]

  • 12. Implication by site-directed mutagenesis of Arg314 and Tyr316 in the coenzyme site of pig mitochondrial NADP-dependent isocitrate dehydrogenase.
    Lee P, Colman RF.
    Arch Biochem Biophys; 2002 May 01; 401(1):81-90. PubMed ID: 12054490
    [Abstract] [Full Text] [Related]

  • 13. Two novel mutant human adenylosuccinate lyases (ASLs) associated with autism and characterization of the equivalent mutant Bacillus subtilis ASL.
    Sivendran S, Patterson D, Spiegel E, McGown I, Cowley D, Colman RF.
    J Biol Chem; 2004 Dec 17; 279(51):53789-97. PubMed ID: 15471876
    [Abstract] [Full Text] [Related]

  • 14. Effect of a new non-cleavable substrate analog on wild-type and serine mutants in the signature sequence of adenylosuccinate lyase of Bacillus subtilis and Homo sapiens.
    Sivendran S, Colman RF.
    Protein Sci; 2008 Jul 17; 17(7):1162-74. PubMed ID: 18469177
    [Abstract] [Full Text] [Related]

  • 15. Role of arginine 439 in substrate binding of 5-aminolevulinate synthase.
    Tan D, Harrison T, Hunter GA, Ferreira GC.
    Biochemistry; 1998 Feb 10; 37(6):1478-84. PubMed ID: 9484217
    [Abstract] [Full Text] [Related]

  • 16. Involvement of arginine 143 in nucleotide substrate binding at the active site of adenylosuccinate synthetase from Escherichia coli.
    Moe OA, Baker-Malcolm JF, Wang W, Kang C, Fromm HJ, Colman RF.
    Biochemistry; 1996 Jul 16; 35(28):9024-33. PubMed ID: 8703905
    [Abstract] [Full Text] [Related]

  • 17. Important roles of hydroxylic amino acid residues in the function of Bacillus subtilis adenylosuccinate lyase.
    Segall ML, Cashman MA, Colman RF.
    Protein Sci; 2007 Mar 16; 16(3):441-8. PubMed ID: 17322529
    [Abstract] [Full Text] [Related]

  • 18. Elucidation of the substrate specificity, kinetic and catalytic mechanism of adenylosuccinate lyase from Plasmodium falciparum.
    Bulusu V, Srinivasan B, Bopanna MP, Balaram H.
    Biochim Biophys Acta; 2009 Apr 16; 1794(4):642-54. PubMed ID: 19111634
    [Abstract] [Full Text] [Related]

  • 19. The structure of adenylosuccinate lyase, an enzyme with dual activity in the de novo purine biosynthetic pathway.
    Toth EA, Yeates TO.
    Structure; 2000 Feb 15; 8(2):163-74. PubMed ID: 10673438
    [Abstract] [Full Text] [Related]

  • 20. Design of an adenosine phosphorylase by active-site modification of murine purine nucleoside phosphorylase. Enzyme kinetics and molecular dynamics simulation of Asn-243 and Lys-244 substitutions of purine nucleoside phosphorylase.
    Maynes JT, Yam W, Jenuth JP, Gang Yuan R, Litster SA, Phipps BM, Snyder FF.
    Biochem J; 1999 Dec 01; 344 Pt 2(Pt 2):585-92. PubMed ID: 10567244
    [Abstract] [Full Text] [Related]

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