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225 related items for PubMed ID: 15198669

  • 1. Phospholipid synthesis is decreased in neuronal tissue in a mouse model of Sandhoff disease.
    Buccoliero R, Bodennec J, Van Echten-Deckert G, Sandhoff K, Futerman AH.
    J Neurochem; 2004 Jul; 90(1):80-8. PubMed ID: 15198669
    [Abstract] [Full Text] [Related]

  • 2. Specific induction of macrophage inflammatory protein 1-alpha in glial cells of Sandhoff disease model mice associated with accumulation of N-acetylhexosaminyl glycoconjugates.
    Tsuji D, Kuroki A, Ishibashi Y, Itakura T, Kuwahara J, Yamanaka S, Itoh K.
    J Neurochem; 2005 Mar; 92(6):1497-507. PubMed ID: 15748167
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  • 3. Mouse models of Tay-Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism.
    Sango K, Yamanaka S, Hoffmann A, Okuda Y, Grinberg A, Westphal H, McDonald MP, Crawley JN, Sandhoff K, Suzuki K, Proia RL.
    Nat Genet; 1995 Oct; 11(2):170-6. PubMed ID: 7550345
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  • 4. Metabolic correction in microglia derived from Sandhoff disease model mice.
    Tsuji D, Kuroki A, Ishibashi Y, Itakura T, Itoh K.
    J Neurochem; 2005 Sep; 94(6):1631-8. PubMed ID: 16092933
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  • 5. Phosphatidylcholine synthesis is elevated in neuronal models of Gaucher disease due to direct activation of CTP:phosphocholine cytidylyltransferase by glucosylceramide.
    Bodennec J, Pelled D, Riebeling C, Trajkovic S, Futerman AH.
    FASEB J; 2002 Nov; 16(13):1814-6. PubMed ID: 12223447
    [Abstract] [Full Text] [Related]

  • 6. Influence of caloric restriction on motor behavior, longevity, and brain lipid composition in Sandhoff disease mice.
    Denny CA, Kasperzyk JL, Gorham KN, Bronson RT, Seyfried TN.
    J Neurosci Res; 2006 May 01; 83(6):1028-38. PubMed ID: 16521125
    [Abstract] [Full Text] [Related]

  • 7. Mice lacking both subunits of lysosomal beta-hexosaminidase display gangliosidosis and mucopolysaccharidosis.
    Sango K, McDonald MP, Crawley JN, Mack ML, Tifft CJ, Skop E, Starr CM, Hoffmann A, Sandhoff K, Suzuki K, Proia RL.
    Nat Genet; 1996 Nov 01; 14(3):348-52. PubMed ID: 8896570
    [Abstract] [Full Text] [Related]

  • 8. Reversion of the biochemical defects in murine embryonic Sandhoff neurons using a bicistronic lentiviral vector encoding hexosaminidase alpha and beta.
    Arfi A, Zisling R, Richard E, Batista L, Poenaru L, Futerman AH, Caillaud C.
    J Neurochem; 2006 Mar 01; 96(6):1572-9. PubMed ID: 16441513
    [Abstract] [Full Text] [Related]

  • 9. N-butyldeoxygalactonojirimycin reduces brain ganglioside and GM2 content in neonatal Sandhoff disease mice.
    Baek RC, Kasperzyk JL, Platt FM, Seyfried TN.
    Neurochem Int; 2008 May 01; 52(6):1125-33. PubMed ID: 18207611
    [Abstract] [Full Text] [Related]

  • 10. Mechanism of abnormal growth in astrocytes derived from a mouse model of GM2 gangliosidosis.
    Kawashima N, Tsuji D, Okuda T, Itoh K, Nakayama K.
    J Neurochem; 2009 Nov 01; 111(4):1031-41. PubMed ID: 19765188
    [Abstract] [Full Text] [Related]

  • 11. Bicistronic lentiviral vector corrects beta-hexosaminidase deficiency in transduced and cross-corrected human Sandhoff fibroblasts.
    Arfi A, Bourgoin C, Basso L, Emiliani C, Tancini B, Chigorno V, Li YT, Orlacchio A, Poenaru L, Sonnino S, Caillaud C.
    Neurobiol Dis; 2005 Nov 01; 20(2):583-93. PubMed ID: 15953731
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  • 15. Widespread distribution of beta-hexosaminidase activity in the brain of a Sandhoff mouse model after coinjection of adenoviral vector and mannitol.
    Bourgoin C, Emiliani C, Kremer EJ, Gelot A, Tancini B, Gravel RA, Drugan C, Orlacchio A, Poenaru L, Caillaud C.
    Gene Ther; 2003 Oct 01; 10(21):1841-9. PubMed ID: 12960974
    [Abstract] [Full Text] [Related]

  • 16. Restricted ketogenic diet enhances the therapeutic action of N-butyldeoxynojirimycin towards brain GM2 accumulation in adult Sandhoff disease mice.
    Denny CA, Heinecke KA, Kim YP, Baek RC, Loh KS, Butters TD, Bronson RT, Platt FM, Seyfried TN.
    J Neurochem; 2010 Jun 01; 113(6):1525-35. PubMed ID: 20374428
    [Abstract] [Full Text] [Related]

  • 17. Mice deficient in all forms of lysosomal beta-hexosaminidase show mucopolysaccharidosis-like pathology.
    Suzuki K, Sango K, Proia RL, Langaman C.
    J Neuropathol Exp Neurol; 1997 Jun 01; 56(6):693-703. PubMed ID: 9184660
    [Abstract] [Full Text] [Related]

  • 18. beta-hexosaminidase lentiviral vectors: transfer into the CNS via systemic administration.
    Kyrkanides S, Miller JH, Brouxhon SM, Olschowka JA, Federoff HJ.
    Brain Res Mol Brain Res; 2005 Feb 18; 133(2):286-98. PubMed ID: 15710246
    [Abstract] [Full Text] [Related]

  • 19. MRS reveals additional hexose N-acetyl resonances in the brain of a mouse model for Sandhoff disease.
    Lowe JP, Stuckey DJ, Awan FR, Jeyakumar M, Neville DC, Platt FM, Griffin JL, Styles P, Blamire AM, Sibson NR.
    NMR Biomed; 2005 Dec 18; 18(8):517-26. PubMed ID: 16206131
    [Abstract] [Full Text] [Related]

  • 20. Plasmid-based gene transfer ameliorates visceral storage in a mouse model of Sandhoff disease.
    Yamaguchi A, Katsuyama K, Suzuki K, Kosaka K, Aoki I, Yamanaka S.
    J Mol Med (Berl); 2003 Mar 18; 81(3):185-93. PubMed ID: 12682727
    [Abstract] [Full Text] [Related]

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