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225 related items for PubMed ID: 15199157

  • 1. IkappaB kinase is an essential component of the Tpl2 signaling pathway.
    Waterfield M, Jin W, Reiley W, Zhang M, Sun SC.
    Mol Cell Biol; 2004 Jul; 24(13):6040-8. PubMed ID: 15199157
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  • 2. Sensitivity of TLR4- and -7-induced NF kappa B1 p105-TPL2-ERK pathway to TNF-receptor-associated-factor-6 revealed by RNAi in mouse macrophages.
    Loniewski KJ, Patial S, Parameswaran N.
    Mol Immunol; 2007 Jul; 44(15):3715-23. PubMed ID: 17507094
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  • 3. Phosphorylation of NF-kappaB1/p105 by oncoprotein kinase Tpl2: implications for a novel mechanism of Tpl2 regulation.
    Babu GR, Jin W, Norman L, Waterfield M, Chang M, Wu X, Zhang M, Sun SC.
    Biochim Biophys Acta; 2006 Feb; 1763(2):174-81. PubMed ID: 16448710
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  • 7. NF-kappaB1/p105 regulates lipopolysaccharide-stimulated MAP kinase signaling by governing the stability and function of the Tpl2 kinase.
    Waterfield MR, Zhang M, Norman LP, Sun SC.
    Mol Cell; 2003 Mar; 11(3):685-94. PubMed ID: 12667451
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  • 10. Tumor progression locus 2-dependent oxidative burst drives phosphorylation of extracellular signal-regulated kinase during TLR3 and 9 signaling.
    Kuriakose T, Rada B, Watford WT.
    J Biol Chem; 2014 Dec 26; 289(52):36089-100. PubMed ID: 25378393
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  • 11. Phosphorylation at Thr-290 regulates Tpl2 binding to NF-kappaB1/p105 and Tpl2 activation and degradation by lipopolysaccharide.
    Cho J, Tsichlis PN.
    Proc Natl Acad Sci U S A; 2005 Feb 15; 102(7):2350-5. PubMed ID: 15699325
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  • 12. Diverse Toll-like receptors utilize Tpl2 to activate extracellular signal-regulated kinase (ERK) in hemopoietic cells.
    Banerjee A, Gugasyan R, McMahon M, Gerondakis S.
    Proc Natl Acad Sci U S A; 2006 Feb 28; 103(9):3274-9. PubMed ID: 16484370
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  • 13. Cot/tpl2 activity is required for TLR-induced activation of the Akt p70 S6k pathway in macrophages: Implications for NO synthase 2 expression.
    López-Peláez M, Soria-Castro I, Boscá L, Fernández M, Alemany S.
    Eur J Immunol; 2011 Jun 28; 41(6):1733-41. PubMed ID: 21469113
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  • 18. Coordinate regulation of TPL-2 and NF-κB signaling in macrophages by NF-κB1 p105.
    Yang HT, Papoutsopoulou S, Belich M, Brender C, Janzen J, Gantke T, Handley M, Ley SC.
    Mol Cell Biol; 2012 Sep 28; 32(17):3438-51. PubMed ID: 22733995
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  • 19. Tpl2 kinase is upregulated in adipose tissue in obesity and may mediate interleukin-1beta and tumor necrosis factor-{alpha} effects on extracellular signal-regulated kinase activation and lipolysis.
    Jager J, Grémeaux T, Gonzalez T, Bonnafous S, Debard C, Laville M, Vidal H, Tran A, Gual P, Le Marchand-Brustel Y, Cormont M, Tanti JF.
    Diabetes; 2010 Jan 28; 59(1):61-70. PubMed ID: 19808894
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  • 20. NF-κB1 p105 suppresses lung tumorigenesis through the Tpl2 kinase but independently of its NF-κB function.
    Sun F, Qu Z, Xiao Y, Zhou J, Burns TF, Stabile LP, Siegfried JM, Xiao G.
    Oncogene; 2016 May 05; 35(18):2299-310. PubMed ID: 26300007
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