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Journal Abstract Search


154 related items for PubMed ID: 15207543

  • 1. Utility of 96 well Caco-2 cell system for increased throughput of P-gp screening in drug discovery.
    Balimane PV, Patel K, Marino A, Chong S.
    Eur J Pharm Biopharm; 2004 Jul; 58(1):99-105. PubMed ID: 15207543
    [Abstract] [Full Text] [Related]

  • 2. Validation of the 96 well Caco-2 cell culture model for high throughput permeability assessment of discovery compounds.
    Marino AM, Yarde M, Patel H, Chong S, Balimane PV.
    Int J Pharm; 2005 Jun 13; 297(1-2):235-41. PubMed ID: 15907606
    [Abstract] [Full Text] [Related]

  • 3. Development of a quantitative LC-MS/MS analytical method coupled with turbulent flow chromatography for digoxin for the in vitro P-gp inhibition assay.
    Smalley J, Marino AM, Xin B, Olah T, Balimane PV.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2007 Jul 01; 854(1-2):260-7. PubMed ID: 17524973
    [Abstract] [Full Text] [Related]

  • 4. Functional assessment of multiple P-glycoprotein (P-gp) probe substrates: influence of cell line and modulator concentration on P-gp activity.
    Taub ME, Podila L, Ely D, Almeida I.
    Drug Metab Dispos; 2005 Nov 01; 33(11):1679-87. PubMed ID: 16093365
    [Abstract] [Full Text] [Related]

  • 5. Development of an in silico model for predicting efflux substrates in Caco-2 cells.
    Zhang L, Balimane PV, Johnson SR, Chong S.
    Int J Pharm; 2007 Oct 01; 343(1-2):98-105. PubMed ID: 17583455
    [Abstract] [Full Text] [Related]

  • 6. Characterization of binding properties to human P-glycoprotein: development of a [3H]verapamil radioligand-binding assay.
    Döppenschmitt S, Langguth P, Regårdh CG, Andersson TB, Hilgendorf C, Spahn-Langguth H.
    J Pharmacol Exp Ther; 1999 Jan 01; 288(1):348-57. PubMed ID: 9862789
    [Abstract] [Full Text] [Related]

  • 7. A combined cell based approach to identify P-glycoprotein substrates and inhibitors in a single assay.
    Balimane PV, Chong S.
    Int J Pharm; 2005 Sep 14; 301(1-2):80-8. PubMed ID: 16023314
    [Abstract] [Full Text] [Related]

  • 8. Development of an on-line extraction turbulent flow chromatography tandem mass spectrometry method for cassette analysis of Caco-2 cell based bi-directional assay samples.
    Smalley J, Kadiyala P, Xin B, Balimane P, Olah T.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2006 Jan 18; 830(2):270-7. PubMed ID: 16307910
    [Abstract] [Full Text] [Related]

  • 9. Accelerated Caco-2 cell permeability model for drug discovery.
    Sevin E, Dehouck L, Fabulas-da Costa A, Cecchelli R, Dehouck MP, Lundquist S, Culot M.
    J Pharmacol Toxicol Methods; 2013 Jan 18; 68(3):334-9. PubMed ID: 23916595
    [Abstract] [Full Text] [Related]

  • 10. Caco-2 cell methodology and inhibition of the P-glycoprotein transport of digoxin by Aloe vera juice.
    Djuv A, Nilsen OG.
    Phytother Res; 2008 Dec 18; 22(12):1623-8. PubMed ID: 19003953
    [Abstract] [Full Text] [Related]

  • 11. Drug penetration model of vinblastine-treated Caco-2 cultures.
    Hellinger E, Bakk ML, Pócza P, Tihanyi K, Vastag M.
    Eur J Pharm Sci; 2010 Sep 11; 41(1):96-106. PubMed ID: 20595016
    [Abstract] [Full Text] [Related]

  • 12. In vitro P-glycoprotein assays to predict the in vivo interactions of P-glycoprotein with drugs in the central nervous system.
    Feng B, Mills JB, Davidson RE, Mireles RJ, Janiszewski JS, Troutman MD, de Morais SM.
    Drug Metab Dispos; 2008 Feb 11; 36(2):268-75. PubMed ID: 17962372
    [Abstract] [Full Text] [Related]

  • 13. Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery.
    Schwab D, Fischer H, Tabatabaei A, Poli S, Huwyler J.
    J Med Chem; 2003 Apr 24; 46(9):1716-25. PubMed ID: 12699389
    [Abstract] [Full Text] [Related]

  • 14. Kinetic identification of membrane transporters that assist P-glycoprotein-mediated transport of digoxin and loperamide through a confluent monolayer of MDCKII-hMDR1 cells.
    Acharya P, O'Connor MP, Polli JW, Ayrton A, Ellens H, Bentz J.
    Drug Metab Dispos; 2008 Feb 24; 36(2):452-60. PubMed ID: 17967933
    [Abstract] [Full Text] [Related]

  • 15. Ultrafast mass spectrometry based bioanalytical method for digoxin supporting an in vitro P-glycoprotein (P-gp) inhibition screen.
    Wagner AD, Kolb JM, Ozbal CC, Herbst JJ, Olah TV, Weller HN, Zvyaga TA, Shou WZ.
    Rapid Commun Mass Spectrom; 2011 May 15; 25(9):1231-40. PubMed ID: 21488121
    [Abstract] [Full Text] [Related]

  • 16. Evaluation of the permeability and P-glycoprotein efflux of carbamazepine and several derivatives across mouse small intestine by the Ussing chamber technique.
    Fortuna A, Alves G, Falcão A, Soares-da-Silva P.
    Epilepsia; 2012 Mar 15; 53(3):529-38. PubMed ID: 22372629
    [Abstract] [Full Text] [Related]

  • 17. Functional role of P-glycoprotein in limiting intestinal absorption of drugs: contribution of passive permeability to P-glycoprotein mediated efflux transport.
    Varma MV, Sateesh K, Panchagnula R.
    Mol Pharm; 2005 Mar 15; 2(1):12-21. PubMed ID: 15804173
    [Abstract] [Full Text] [Related]

  • 18. Prediction of P-glycoprotein substrates by a support vector machine approach.
    Xue Y, Yap CW, Sun LZ, Cao ZW, Wang JF, Chen YZ.
    J Chem Inf Comput Sci; 2004 Mar 15; 44(4):1497-505. PubMed ID: 15272858
    [Abstract] [Full Text] [Related]

  • 19. Drug-drug interactions mediated through P-glycoprotein: clinical relevance and in vitro-in vivo correlation using digoxin as a probe drug.
    Fenner KS, Troutman MD, Kempshall S, Cook JA, Ware JA, Smith DA, Lee CA.
    Clin Pharmacol Ther; 2009 Feb 15; 85(2):173-81. PubMed ID: 18987624
    [Abstract] [Full Text] [Related]

  • 20. Reciprocal competition between lipid nanocapsules and P-gp for paclitaxel transport across Caco-2 cells.
    Roger E, Lagarce F, Garcion E, Benoit JP.
    Eur J Pharm Sci; 2010 Aug 11; 40(5):422-9. PubMed ID: 20438839
    [Abstract] [Full Text] [Related]


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