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Journal Abstract Search

173 related items for PubMed ID: 15207859

  • 1. p38alpha stress-activated protein kinase phosphorylates neurofilaments and is associated with neurofilament pathology in amyotrophic lateral sclerosis.
    Ackerley S, Grierson AJ, Banner S, Perkinton MS, Brownlees J, Byers HL, Ward M, Thornhill P, Hussain K, Waby JS, Anderton BH, Cooper JD, Dingwall C, Leigh PN, Shaw CE, Miller CC.
    Mol Cell Neurosci; 2004 Jun; 26(2):354-64. PubMed ID: 15207859
    [Abstract] [Full Text] [Related]

  • 2. Persistent activation of p38 mitogen-activated protein kinase in a mouse model of familial amyotrophic lateral sclerosis correlates with disease progression.
    Tortarolo M, Veglianese P, Calvaresi N, Botturi A, Rossi C, Giorgini A, Migheli A, Bendotti C.
    Mol Cell Neurosci; 2003 Jun; 23(2):180-92. PubMed ID: 12812752
    [Abstract] [Full Text] [Related]

  • 3. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
    Jaarsma D, Haasdijk ED, Grashorn JA, Hawkins R, van Duijn W, Verspaget HW, London J, Holstege JC.
    Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261
    [Abstract] [Full Text] [Related]

  • 4. Activated p38MAPK is a novel component of the intracellular inclusions found in human amyotrophic lateral sclerosis and mutant SOD1 transgenic mice.
    Bendotti C, Atzori C, Piva R, Tortarolo M, Strong MJ, DeBiasi S, Migheli A.
    J Neuropathol Exp Neurol; 2004 Feb; 63(2):113-9. PubMed ID: 14989597
    [Abstract] [Full Text] [Related]

  • 5. Activation of the stress-activated MAP kinase, p38, but not JNK in cortical motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in transgenic mice.
    Holasek SS, Wengenack TM, Kandimalla KK, Montano C, Gregor DM, Curran GL, Poduslo JF.
    Brain Res; 2005 May 31; 1045(1-2):185-98. PubMed ID: 15910777
    [Abstract] [Full Text] [Related]

  • 6. Degeneration of axons in spinal white matter in G93A mSOD1 mouse characterized by NFL and α-internexin immunoreactivity.
    King AE, Blizzard CA, Southam KA, Vickers JC, Dickson TC.
    Brain Res; 2012 Jul 17; 1465():90-100. PubMed ID: 22609817
    [Abstract] [Full Text] [Related]

  • 7. Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions.
    Nguyen MD, Larivière RC, Julien JP.
    Neuron; 2001 Apr 17; 30(1):135-47. PubMed ID: 11343650
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of p38 mitogen activated protein kinase activation and mutant SOD1(G93A)-induced motor neuron death.
    Dewil M, dela Cruz VF, Van Den Bosch L, Robberecht W.
    Neurobiol Dis; 2007 May 17; 26(2):332-41. PubMed ID: 17346981
    [Abstract] [Full Text] [Related]

  • 9. Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant.
    Williamson TL, Bruijn LI, Zhu Q, Anderson KL, Anderson SD, Julien JP, Cleveland DW.
    Proc Natl Acad Sci U S A; 1998 Aug 04; 95(16):9631-6. PubMed ID: 9689132
    [Abstract] [Full Text] [Related]

  • 10. Cyclin dependent kinase-5 (CDK-5) phosphorylates neurofilament heavy (NF-H) chain to generate epitopes for antibodies that label neurofilament accumulations in amyotrophic lateral sclerosis (ALS) and is present in affected motor neurones in ALS.
    Bajaj NP, al-Sarraj ST, Leigh PN, Anderson V, Miller CC.
    Prog Neuropsychopharmacol Biol Psychiatry; 1999 Jul 04; 23(5):833-50. PubMed ID: 10509378
    [Abstract] [Full Text] [Related]

  • 11. Accumulation of neurofilaments and SOD1-immunoreactive products in a patient with familial amyotrophic lateral sclerosis with I113T SOD1 mutation.
    Kokubo Y, Kuzuhara S, Narita Y, Kikugawa K, Nakano R, Inuzuka T, Tsuji S, Watanabe M, Miyazaki T, Murayama S, Ihara Y.
    Arch Neurol; 1999 Dec 04; 56(12):1506-8. PubMed ID: 10593307
    [Abstract] [Full Text] [Related]

  • 12. Altered axonal architecture by removal of the heavily phosphorylated neurofilament tail domains strongly slows superoxide dismutase 1 mutant-mediated ALS.
    Lobsiger CS, Garcia ML, Ward CM, Cleveland DW.
    Proc Natl Acad Sci U S A; 2005 Jul 19; 102(29):10351-6. PubMed ID: 16002469
    [Abstract] [Full Text] [Related]

  • 13. Interaction between familial amyotrophic lateral sclerosis (ALS)-linked SOD1 mutants and the dynein complex.
    Zhang F, Ström AL, Fukada K, Lee S, Hayward LJ, Zhu H.
    J Biol Chem; 2007 Jun 01; 282(22):16691-9. PubMed ID: 17403682
    [Abstract] [Full Text] [Related]

  • 14. Amyotrophic lateral sclerosis associated with genetic abnormalities in the gene encoding Cu/Zn superoxide dismutase: molecular pathology of five new cases, and comparison with previous reports and 73 sporadic cases of ALS.
    Ince PG, Tomkins J, Slade JY, Thatcher NM, Shaw PJ.
    J Neuropathol Exp Neurol; 1998 Oct 01; 57(10):895-904. PubMed ID: 9786240
    [Abstract] [Full Text] [Related]

  • 15. Lessons from models of SOD1-linked familial ALS.
    Bendotti C, Carrì MT.
    Trends Mol Med; 2004 Aug 01; 10(8):393-400. PubMed ID: 15310460
    [Abstract] [Full Text] [Related]

  • 16. Determinants of rapid disease progression in ALS.
    Yamanaka K, Cleveland DW.
    Neurology; 2005 Dec 27; 65(12):1859-60. PubMed ID: 16380607
    [No Abstract] [Full Text] [Related]

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  • 18. Phosphatase and tensin homologue/protein kinase B pathway linked to motor neuron survival in human superoxide dismutase 1-related amyotrophic lateral sclerosis.
    Kirby J, Ning K, Ferraiuolo L, Heath PR, Ismail A, Kuo SW, Valori CF, Cox L, Sharrack B, Wharton SB, Ince PG, Shaw PJ, Azzouz M.
    Brain; 2011 Feb 27; 134(Pt 2):506-17. PubMed ID: 21228060
    [Abstract] [Full Text] [Related]

  • 19. Metallothionein expression is altered in a transgenic murine model of familial amyotrophic lateral sclerosis.
    Gong YH, Elliott JL.
    Exp Neurol; 2000 Mar 27; 162(1):27-36. PubMed ID: 10716886
    [Abstract] [Full Text] [Related]

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