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292 related items for PubMed ID: 15212842

  • 1. APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1.
    Jankowsky JL, Slunt HH, Gonzales V, Jenkins NA, Copeland NG, Borchelt DR.
    Neurobiol Aging; 2004 Aug; 25(7):885-92. PubMed ID: 15212842
    [Abstract] [Full Text] [Related]

  • 2. Deposition of mouse amyloid beta in human APP/PS1 double and single AD model transgenic mice.
    van Groen T, Kiliaan AJ, Kadish I.
    Neurobiol Dis; 2006 Sep; 23(3):653-62. PubMed ID: 16829076
    [Abstract] [Full Text] [Related]

  • 3. Additive effects of PS1 and APP mutations on secretion of the 42-residue amyloid beta-protein.
    Citron M, Eckman CB, Diehl TS, Corcoran C, Ostaszewski BL, Xia W, Levesque G, St George Hyslop P, Younkin SG, Selkoe DJ.
    Neurobiol Dis; 1998 Aug; 5(2):107-16. PubMed ID: 9746908
    [Abstract] [Full Text] [Related]

  • 4. Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities.
    Savonenko A, Xu GM, Melnikova T, Morton JL, Gonzales V, Wong MP, Price DL, Tang F, Markowska AL, Borchelt DR.
    Neurobiol Dis; 2005 Apr; 18(3):602-17. PubMed ID: 15755686
    [Abstract] [Full Text] [Related]

  • 5. Age-related evolution of amyloid burden, iron load, and MR relaxation times in a transgenic mouse model of Alzheimer's disease.
    El Tannir El Tayara N, Delatour B, Le Cudennec C, Guégan M, Volk A, Dhenain M.
    Neurobiol Dis; 2006 Apr; 22(1):199-208. PubMed ID: 16337798
    [Abstract] [Full Text] [Related]

  • 6. Alzheimer's disease-like neuropathology of gene-targeted APP-SLxPS1mut mice expressing the amyloid precursor protein at endogenous levels.
    Köhler C, Ebert U, Baumann K, Schröder H.
    Neurobiol Dis; 2005 Nov; 20(2):528-40. PubMed ID: 15921918
    [Abstract] [Full Text] [Related]

  • 7. Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway.
    Jaffar S, Counts SE, Ma SY, Dadko E, Gordon MN, Morgan D, Mufson EJ.
    Exp Neurol; 2001 Aug; 170(2):227-43. PubMed ID: 11476589
    [Abstract] [Full Text] [Related]

  • 8. Neurodegenerative changes associated with beta-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes.
    Kurt MA, Davies DC, Kidd M, Duff K, Rolph SC, Jennings KH, Howlett DR.
    Exp Neurol; 2001 Sep; 171(1):59-71. PubMed ID: 11520121
    [Abstract] [Full Text] [Related]

  • 9. Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1.
    Szapacs ME, Numis AL, Andrews AM.
    Neurobiol Dis; 2004 Aug; 16(3):572-80. PubMed ID: 15262269
    [Abstract] [Full Text] [Related]

  • 10. Neuropathological characterization of mutant amyloid precursor protein yeast artificial chromosome transgenic mice.
    Kulnane LS, Lamb BT.
    Neurobiol Dis; 2001 Dec; 8(6):982-92. PubMed ID: 11741394
    [Abstract] [Full Text] [Related]

  • 11. Cycloxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer's disease in a sex-dimorphic pattern.
    Melnikova T, Savonenko A, Wang Q, Liang X, Hand T, Wu L, Kaufmann WE, Vehmas A, Andreasson KI.
    Neuroscience; 2006 Sep 01; 141(3):1149-62. PubMed ID: 16753269
    [Abstract] [Full Text] [Related]

  • 12. Altered levels and distribution of IGF-II/M6P receptor and lysosomal enzymes in mutant APP and APP + PS1 transgenic mouse brains.
    Amritraj A, Hawkes C, Phinney AL, Mount HT, Scott CD, Westaway D, Kar S.
    Neurobiol Aging; 2009 Jan 01; 30(1):54-70. PubMed ID: 17561313
    [Abstract] [Full Text] [Related]

  • 13. Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes.
    McGowan E, Sanders S, Iwatsubo T, Takeuchi A, Saido T, Zehr C, Yu X, Uljon S, Wang R, Mann D, Dickson D, Duff K.
    Neurobiol Dis; 1999 Aug 01; 6(4):231-44. PubMed ID: 10448051
    [Abstract] [Full Text] [Related]

  • 14. Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse.
    Gordon MN, Holcomb LA, Jantzen PT, DiCarlo G, Wilcock D, Boyett KW, Connor K, Melachrino J, O'Callaghan JP, Morgan D.
    Exp Neurol; 2002 Feb 01; 173(2):183-95. PubMed ID: 11822882
    [Abstract] [Full Text] [Related]

  • 15. Central cholinergic functions in human amyloid precursor protein knock-in/presenilin-1 transgenic mice.
    Hartmann J, Erb C, Ebert U, Baumann KH, Popp A, König G, Klein J.
    Neuroscience; 2004 Feb 01; 125(4):1009-17. PubMed ID: 15120860
    [Abstract] [Full Text] [Related]

  • 16. Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease.
    Garcia-Alloza M, Robbins EM, Zhang-Nunes SX, Purcell SM, Betensky RA, Raju S, Prada C, Greenberg SM, Bacskai BJ, Frosch MP.
    Neurobiol Dis; 2006 Dec 01; 24(3):516-24. PubMed ID: 17029828
    [Abstract] [Full Text] [Related]

  • 17. Progressive age-related development of Alzheimer-like pathology in APP/PS1 mice.
    Trinchese F, Liu S, Battaglia F, Walter S, Mathews PM, Arancio O.
    Ann Neurol; 2004 Jun 01; 55(6):801-14. PubMed ID: 15174014
    [Abstract] [Full Text] [Related]

  • 18. Permeability of proteins at the blood-brain barrier in the normal adult mouse and double transgenic mouse model of Alzheimer's disease.
    Poduslo JF, Curran GL, Wengenack TM, Malester B, Duff K.
    Neurobiol Dis; 2001 Aug 01; 8(4):555-67. PubMed ID: 11493021
    [Abstract] [Full Text] [Related]

  • 19. Increase in presenilin 1 (PS1) levels in senescence-accelerated mice (SAMP8) may indirectly impair memory by affecting amyloid precursor protein (APP) processing.
    Kumar VB, Franko M, Banks WA, Kasinadhuni P, Farr SA, Vyas K, Choudhuri V, Morley JE.
    J Exp Biol; 2009 Feb 01; 212(Pt 4):494-8. PubMed ID: 19181896
    [Abstract] [Full Text] [Related]

  • 20. Regional metabolic alteration of Alzheimer's disease in mouse brain expressing mutant human APP-PS1 by 1H HR-MAS.
    Woo DC, Lee SH, Lee DW, Kim SY, Kim GY, Rhim HS, Choi CB, Kim HY, Lee CU, Choe BY.
    Behav Brain Res; 2010 Jul 29; 211(1):125-31. PubMed ID: 20307581
    [Abstract] [Full Text] [Related]

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