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Journal Abstract Search

510 related items for PubMed ID: 15213302

  • 1. Laulimalide and paclitaxel: a comparison of their effects on tubulin assembly and their synergistic action when present simultaneously.
    Gapud EJ, Bai R, Ghosh AK, Hamel E.
    Mol Pharmacol; 2004 Jul; 66(1):113-21. PubMed ID: 15213302
    [Abstract] [Full Text] [Related]

  • 2. Cyclostreptin (FR182877), an antitumor tubulin-polymerizing agent deficient in enhancing tubulin assembly despite its high affinity for the taxoid site.
    Edler MC, Buey RM, Gussio R, Marcus AI, Vanderwal CD, Sorensen EJ, Díaz JF, Giannakakou P, Hamel E.
    Biochemistry; 2005 Aug 30; 44(34):11525-38. PubMed ID: 16114889
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  • 3. Laulimalide and synthetic laulimalide analogues are synergistic with paclitaxel and 2-methoxyestradiol.
    Clark EA, Hills PM, Davidson BS, Wender PA, Mooberry SL.
    Mol Pharm; 2006 Aug 30; 3(4):457-67. PubMed ID: 16889440
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  • 7. The microtubule-stabilizing agent discodermolide competitively inhibits the binding of paclitaxel (Taxol) to tubulin polymers, enhances tubulin nucleation reactions more potently than paclitaxel, and inhibits the growth of paclitaxel-resistant cells.
    Kowalski RJ, Giannakakou P, Gunasekera SP, Longley RE, Day BW, Hamel E.
    Mol Pharmacol; 1997 Oct 30; 52(4):613-22. PubMed ID: 9380024
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  • 8. Tubulin assembly, taxoid site binding, and cellular effects of the microtubule-stabilizing agent dictyostatin.
    Madiraju C, Edler MC, Hamel E, Raccor BS, Balachandran R, Zhu G, Giuliano KA, Vogt A, Shin Y, Fournier JH, Fukui Y, Brückner AM, Curran DP, Day BW.
    Biochemistry; 2005 Nov 15; 44(45):15053-63. PubMed ID: 16274252
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  • 9. Laulimalide and isolaulimalide, new paclitaxel-like microtubule-stabilizing agents.
    Mooberry SL, Tien G, Hernandez AH, Plubrukarn A, Davidson BS.
    Cancer Res; 1999 Feb 01; 59(3):653-60. PubMed ID: 9973214
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  • 10. The coral-derived natural products eleutherobin and sarcodictyins A and B: effects on the assembly of purified tubulin with and without microtubule-associated proteins and binding at the polymer taxoid site.
    Hamel E, Sackett DL, Vourloumis D, Nicolaou KC.
    Biochemistry; 1999 Apr 27; 38(17):5490-8. PubMed ID: 10220336
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  • 11. The microtubule stabilizing agent laulimalide does not bind in the taxoid site, kills cells resistant to paclitaxel and epothilones, and may not require its epoxide moiety for activity.
    Pryor DE, O'Brate A, Bilcer G, Díaz JF, Wang Y, Wang Y, Kabaki M, Jung MK, Andreu JM, Ghosh AK, Giannakakou P, Hamel E.
    Biochemistry; 2002 Jul 23; 41(29):9109-15. PubMed ID: 12119025
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  • 12. Mutations at leucine 215 of beta-tubulin affect paclitaxel sensitivity by two distinct mechanisms.
    Wang Y, Yin S, Blade K, Cooper G, Menick DR, Cabral F.
    Biochemistry; 2006 Jan 10; 45(1):185-94. PubMed ID: 16388594
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  • 13. In vitro and in vivo anticancer activities of synthetic (-)-laulimalide, a marine natural product microtubule stabilizing agent.
    Liu J, Towle MJ, Cheng H, Saxton P, Reardon C, Wu J, Murphy EA, Kuznetsov G, Johannes CW, Tremblay MR, Zhao H, Pesant M, Fang FG, Vermeulen MW, Gallagher BM, Littlefield BA.
    Anticancer Res; 2007 Jan 10; 27(3B):1509-18. PubMed ID: 17595769
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  • 16. Phosphate release during microtubule assembly: what stabilizes growing microtubules?
    Vandecandelaere A, Brune M, Webb MR, Martin SR, Bayley PM.
    Biochemistry; 1999 Jun 22; 38(25):8179-88. PubMed ID: 10387063
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  • 17. Discodermolide, a cytotoxic marine agent that stabilizes microtubules more potently than taxol.
    ter Haar E, Kowalski RJ, Hamel E, Lin CM, Longley RE, Gunasekera SP, Rosenkranz HS, Day BW.
    Biochemistry; 1996 Jan 09; 35(1):243-50. PubMed ID: 8555181
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  • 19. Spongistatin 1, a highly cytotoxic, sponge-derived, marine natural product that inhibits mitosis, microtubule assembly, and the binding of vinblastine to tubulin.
    Bai R, Cichacz ZA, Herald CL, Pettit GR, Hamel E.
    Mol Pharmacol; 1993 Oct 09; 44(4):757-66. PubMed ID: 8232226
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  • 20. Concerning the chemical nature of tubulin subunits that cap and stabilize microtubules.
    Caplow M, Fee L.
    Biochemistry; 2003 Feb 25; 42(7):2122-6. PubMed ID: 12590601
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