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Journal Abstract Search

165 related items for PubMed ID: 15225612

  • 1.
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  • 2. A novel polymorphism of human CYP2A6 gene CYP2A6*17 has an amino acid substitution (V365M) that decreases enzymatic activity in vitro and in vivo.
    Fukami T, Nakajima M, Yoshida R, Tsuchiya Y, Fujiki Y, Katoh M, McLeod HL, Yokoi T.
    Clin Pharmacol Ther; 2004 Dec; 76(6):519-27. PubMed ID: 15592323
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  • 3. CYP2A7 polymorphic alleles confound the genotyping of CYP2A6*4A allele.
    Fukami T, Nakajima M, Sakai H, McLeod HL, Yokoi T.
    Pharmacogenomics J; 2006 Dec; 6(6):401-12. PubMed ID: 16636685
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  • 5. Comparison of cytochrome P450 2A6 polymorphism frequencies in Caucasians and African-Americans using a new one-step PCR-RFLP genotyping method.
    Paschke T, Riefler M, Schuler-Metz A, Wolz L, Scherer G, McBride CM, Bepler G.
    Toxicology; 2001 Nov 30; 168(3):259-68. PubMed ID: 11684323
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  • 6. Characterization of a genotype previously designated as CYP2A6 D-type: CYP2A6*4B, another entire gene deletion allele of the CYP2A6 gene in Japanese.
    Ariyoshi N, Sekine H, Saito K, Kamataki T.
    Pharmacogenetics; 2002 Aug 30; 12(6):501-4. PubMed ID: 12172220
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  • 8. Effects of polymorphism in promoter region of human CYP2A6 gene (CYP2A6*9) on expression level of messenger ribonucleic acid and enzymatic activity in vivo and in vitro.
    Yoshida R, Nakajima M, Nishimura K, Tokudome S, Kwon JT, Yokoi T.
    Clin Pharmacol Ther; 2003 Jul 30; 74(1):69-76. PubMed ID: 12844137
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  • 9. A novel CYP2A6*20 allele found in African-American population produces a truncated protein lacking enzymatic activity.
    Fukami T, Nakajima M, Higashi E, Yamanaka H, McLeod HL, Yokoi T.
    Biochem Pharmacol; 2005 Sep 01; 70(5):801-8. PubMed ID: 15993850
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  • 10. Characterization of a novel CYP2A7/CYP2A6 hybrid allele (CYP2A6*12) that causes reduced CYP2A6 activity.
    Oscarson M, McLellan RA, Asp V, Ledesma M, Bernal Ruiz ML, Sinues B, Rautio A, Ingelman-Sundberg M.
    Hum Mutat; 2002 Oct 01; 20(4):275-83. PubMed ID: 12325023
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  • 11. Identification and characterisation of novel polymorphisms in the CYP2A locus: implications for nicotine metabolism.
    Oscarson M, McLellan RA, Gullstén H, Agúndez JA, Benítez J, Rautio A, Raunio H, Pelkonen O, Ingelman-Sundberg M.
    FEBS Lett; 1999 Oct 29; 460(2):321-7. PubMed ID: 10544257
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  • 12. The significance of the homozygous CYP2A6 deletion on nicotine metabolism: a new genotyping method of CYP2A6 using a single PCR-RFLP.
    Kitagawa K, Kunugita N, Katoh T, Yang M, Kawamoto T.
    Biochem Biophys Res Commun; 1999 Aug 19; 262(1):146-51. PubMed ID: 10448083
    [Abstract] [Full Text] [Related]

  • 13. High prevalence of cytochrome P450 2A6*1A alleles in a black African population of Ghana.
    Gyamfi MA, Fujieda M, Kiyotani K, Yamazaki H, Kamataki T.
    Eur J Clin Pharmacol; 2005 Feb 19; 60(12):855-7. PubMed ID: 15660270
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  • 15. CYP2A6 and CYP2E1 polymorphisms in a Brazilian population living in Rio de Janeiro.
    Rossini A, Lima SS, Rapozo DC, Faria M, Albano RM, Pinto LF.
    Braz J Med Biol Res; 2006 Feb 19; 39(2):195-201. PubMed ID: 16470306
    [Abstract] [Full Text] [Related]

  • 16. Characterisation and PCR-based detection of a CYP2A6 gene deletion found at a high frequency in a Chinese population.
    Oscarson M, McLellan RA, Gullstén H, Yue QY, Lang MA, Bernal ML, Sinues B, Hirvonen A, Raunio H, Pelkonen O, Ingelman-Sundberg M.
    FEBS Lett; 1999 Apr 01; 448(1):105-10. PubMed ID: 10217419
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  • 17. Metabolic profile of nicotine in subjects whose CYP2A6 gene is deleted.
    Yamanaka H, Nakajima M, Nishimura K, Yoshida R, Fukami T, Katoh M, Yokoi T.
    Eur J Pharm Sci; 2004 Aug 01; 22(5):419-25. PubMed ID: 15265511
    [Abstract] [Full Text] [Related]

  • 18. A new deleted allele in the human cytochrome P450 2A6 (CYP2A6) gene found in individuals showing poor metabolic capacity to coumarin and (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502).
    Nunoya K, Yokoi T, Kimura K, Inoue K, Kodama T, Funayama M, Nagashima K, Funae Y, Green C, Kinoshita M, Kamataki T.
    Pharmacogenetics; 1998 Jun 01; 8(3):239-49. PubMed ID: 9682269
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  • 19. A nicotine C-oxidase gene (CYP2A6) polymorphism important for promoter activity.
    Pitarque M, von Richter O, Rodríguez-Antona C, Wang J, Oscarson M, Ingelman-Sundberg M.
    Hum Mutat; 2004 Mar 01; 23(3):258-66. PubMed ID: 14974084
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  • 20. A novel single nucleotide polymorphism altering stability and activity of CYP2a6.
    Ariyoshi N, Sawamura Y, Kamataki T.
    Biochem Biophys Res Commun; 2001 Mar 02; 281(3):810-4. PubMed ID: 11237731
    [Abstract] [Full Text] [Related]

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