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Journal Abstract Search

286 related items for PubMed ID: 15239662

  • 1.
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  • 2. Sulfonyl-containing nucleoside phosphotriesters and phosphoramidates as novel anticancer prodrugs of 5-fluoro-2'-deoxyuridine 5'-monophosphate (FdUMP).
    Sun YW, Chen KM, Kwon CH.
    Mol Pharm; 2006; 3(2):161-73. PubMed ID: 16579645
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  • 4. Design, synthesis, and biological evaluation of cyclic and acyclic nitrobenzylphosphoramide mustards for E. coli nitroreductase activation.
    Jiang Y, Han J, Yu C, Vass SO, Searle PF, Browne P, Knox RJ, Hu L.
    J Med Chem; 2006 Jul 13; 49(14):4333-43. PubMed ID: 16821793
    [Abstract] [Full Text] [Related]

  • 5. Synthesis of novel androgen-linked phosphoramide mustard prodrugs and growth-inhibitory activity in human breast cancer cells.
    Roth T, Tang W, Eisenbrand G.
    Anticancer Drug Des; 1995 Dec 13; 10(8):655-66. PubMed ID: 8595124
    [Abstract] [Full Text] [Related]

  • 6. Nitroaryl phosphoramides as novel prodrugs for E. coli nitroreductase activation in enzyme prodrug therapy.
    Hu L, Yu C, Jiang Y, Han J, Li Z, Browne P, Race PR, Knox RJ, Searle PF, Hyde EI.
    J Med Chem; 2003 Nov 06; 46(23):4818-21. PubMed ID: 14584930
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  • 8. Acyloxymethyl esters of isophosphoramide mustard as new anticancer prodrugs.
    Cytarska J, Misiura K, Filip-Psurska B, Wietrzyk J.
    Acta Pol Pharm; 2013 Nov 06; 70(3):481-7. PubMed ID: 23757939
    [Abstract] [Full Text] [Related]

  • 9. Aldophosphamide acetal diacetate and structural analogues: synthesis and cytotoxicity studies.
    Wang YQ, Farquhar D.
    J Med Chem; 1991 Jan 06; 34(1):197-203. PubMed ID: 1992116
    [Abstract] [Full Text] [Related]

  • 10. Quinols as novel therapeutic agents. 2.(1) 4-(1-Arylsulfonylindol-2-yl)-4-hydroxycyclohexa-2,5-dien-1-ones and related agents as potent and selective antitumor agents.
    Berry JM, Bradshaw TD, Fichtner I, Ren R, Schwalbe CH, Wells G, Chew EH, Stevens MF, Westwell AD.
    J Med Chem; 2005 Jan 27; 48(2):639-44. PubMed ID: 15658878
    [Abstract] [Full Text] [Related]

  • 11. Novel fluorinated prodrugs for activation by carboxypeptidase G2 showing good in vivo antitumor activity in gene-directed enzyme prodrug therapy.
    Davies LC, Friedlos F, Hedley D, Martin J, Ogilvie LM, Scanlon IJ, Springer CJ.
    J Med Chem; 2005 Aug 11; 48(16):5321-8. PubMed ID: 16078849
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis, and biological evaluation of indolequinone phosphoramidate prodrugs targeted to DT-diaphorase.
    Hernick M, Flader C, Borch RF.
    J Med Chem; 2002 Aug 01; 45(16):3540-8. PubMed ID: 12139465
    [Abstract] [Full Text] [Related]

  • 13. Significant differences in biological parameters between prodrugs cleavable by carboxypeptidase G2 that generate 3,5-difluoro-phenol and -aniline nitrogen mustards in gene-directed enzyme prodrug therapy systems.
    Niculescu-Duvaz I, Scanlon I, Niculescu-Duvaz D, Friedlos F, Martin J, Marais R, Springer CJ.
    J Med Chem; 2004 May 06; 47(10):2651-8. PubMed ID: 15115406
    [Abstract] [Full Text] [Related]

  • 14. Phenylalanyl-aminocyclophosphamides as model prodrugs for proteolytic activation: synthesis, stability, and stereochemical requirements for enzymatic cleavage.
    Jiang Y, Hu L.
    Bioorg Med Chem Lett; 2007 Jan 15; 17(2):517-21. PubMed ID: 17064897
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and structure-activity relationships for 2,4-dinitrobenzamide-5-mustards as prodrugs for the Escherichia coli nfsB nitroreductase in gene therapy.
    Atwell GJ, Yang S, Pruijn FB, Pullen SM, Hogg A, Patterson AV, Wilson WR, Denny WA.
    J Med Chem; 2007 Mar 22; 50(6):1197-212. PubMed ID: 17326614
    [Abstract] [Full Text] [Related]

  • 16. Isophosphoramide mustard analogues as prodrugs for anticancer gene-directed enzyme-prodrug therapy (GDEPT).
    Misiura K, Szymanowicz D, Kuśnierczyk H, Wietrzyk J, Opolski A.
    Acta Biochim Pol; 2002 Mar 22; 49(1):169-76. PubMed ID: 12136937
    [Abstract] [Full Text] [Related]

  • 17. Antitumor agents 253. Design, synthesis, and antitumor evaluation of novel 9-substituted phenanthrene-based tylophorine derivatives as potential anticancer agents.
    Wei L, Shi Q, Bastow KF, Brossi A, Morris-Natschke SL, Nakagawa-Goto K, Wu TS, Pan SL, Teng CM, Lee KH.
    J Med Chem; 2007 Jul 26; 50(15):3674-80. PubMed ID: 17585747
    [Abstract] [Full Text] [Related]

  • 18. Aziridinyldinitrobenzamides: synthesis and structure-activity relationships for activation by E. coli nitroreductase.
    Helsby NA, Atwell GJ, Yang S, Palmer BD, Anderson RF, Pullen SM, Ferry DM, Hogg A, Wilson WR, Denny WA.
    J Med Chem; 2004 Jun 03; 47(12):3295-307. PubMed ID: 15163209
    [Abstract] [Full Text] [Related]

  • 19. In vitro optimization of non-small cell lung cancer activity with troxacitabine, L-1,3-dioxolane-cytidine, prodrugs.
    Radi M, Adema AD, Daft JR, Cho JH, Hoebe EK, Alexander LE, Peters GJ, Chu CK.
    J Med Chem; 2007 May 03; 50(9):2249-53. PubMed ID: 17419604
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and evaluation of nitroheterocyclic carbamate prodrugs for use with nitroreductase-mediated gene-directed enzyme prodrug therapy.
    Hay MP, Anderson RF, Ferry DM, Wilson WR, Denny WA.
    J Med Chem; 2003 Dec 04; 46(25):5533-45. PubMed ID: 14640560
    [Abstract] [Full Text] [Related]

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