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206 related items for PubMed ID: 15248754

  • 1. Intra-allelic suppression of a mutation that stabilizes microtubules and confers resistance to colcemid.
    Wang Y, Veeraraghavan S, Cabral F.
    Biochemistry; 2004 Jul 20; 43(28):8965-73. PubMed ID: 15248754
    [Abstract] [Full Text] [Related]

  • 2. Mutations at leucine 215 of beta-tubulin affect paclitaxel sensitivity by two distinct mechanisms.
    Wang Y, Yin S, Blade K, Cooper G, Menick DR, Cabral F.
    Biochemistry; 2006 Jan 10; 45(1):185-94. PubMed ID: 16388594
    [Abstract] [Full Text] [Related]

  • 3. Mutations in alpha- and beta-tubulin that stabilize microtubules and confer resistance to colcemid and vinblastine.
    Hari M, Wang Y, Veeraraghavan S, Cabral F.
    Mol Cancer Ther; 2003 Jul 10; 2(7):597-605. PubMed ID: 12883031
    [Abstract] [Full Text] [Related]

  • 4. Overexpression of an epitope-tagged beta-tubulin in Chinese hamster ovary cells causes an increase in endogenous alpha-tubulin synthesis.
    Gonzalez-Garay ML, Cabral F.
    Cell Motil Cytoskeleton; 1995 Jul 10; 31(4):259-72. PubMed ID: 7553913
    [Abstract] [Full Text] [Related]

  • 5. Amino acid substitutions at proline 220 of beta-tubulin confer resistance to paclitaxel and colcemid.
    Yin S, Cabral F, Veeraraghavan S.
    Mol Cancer Ther; 2007 Oct 10; 6(10):2798-806. PubMed ID: 17938271
    [Abstract] [Full Text] [Related]

  • 6. Expression of class III beta-tubulin reduces microtubule assembly and confers resistance to paclitaxel.
    Hari M, Yang H, Zeng C, Canizales M, Cabral F.
    Cell Motil Cytoskeleton; 2003 Sep 10; 56(1):45-56. PubMed ID: 12905530
    [Abstract] [Full Text] [Related]

  • 7. Paclitaxel resistance in cells with reduced beta-tubulin.
    Wang Y, Cabral F.
    Biochim Biophys Acta; 2005 Jun 30; 1744(2):245-55. PubMed ID: 15950754
    [Abstract] [Full Text] [Related]

  • 8. Tumor cells resistant to a microtubule-depolymerizing hemiasterlin analogue, HTI-286, have mutations in alpha- or beta-tubulin and increased microtubule stability.
    Poruchynsky MS, Kim JH, Nogales E, Annable T, Loganzo F, Greenberger LM, Sackett DL, Fojo T.
    Biochemistry; 2004 Nov 09; 43(44):13944-54. PubMed ID: 15518543
    [Abstract] [Full Text] [Related]

  • 9. Alterations in gamma-actin and tubulin-targeted drug resistance in childhood leukemia.
    Verrills NM, Po'uha ST, Liu ML, Liaw TY, Larsen MR, Ivery MT, Marshall GM, Gunning PW, Kavallaris M.
    J Natl Cancer Inst; 2006 Oct 04; 98(19):1363-74. PubMed ID: 17018783
    [Abstract] [Full Text] [Related]

  • 10. Revertants of a Chinese hamster ovary cell mutant with an altered beta-tubulin: evidence that the altered tubulin confers both colcemid resistance and temperature sensitivity on the cell.
    Cabral F, Abraham I, Gottesman MM.
    Mol Cell Biol; 1982 Jun 04; 2(6):720-9. PubMed ID: 14582168
    [Abstract] [Full Text] [Related]

  • 11. Cross-resistance of vinblastine- and taxol-resistant mutants of Chinese hamster ovary cells to other anticancer drugs.
    Gupta RS.
    Cancer Treat Rep; 1985 May 04; 69(5):515-21. PubMed ID: 2860971
    [Abstract] [Full Text] [Related]

  • 12. beta-Tubulin mutations are associated with resistance to 2-methoxyestradiol in MDA-MB-435 cancer cells.
    Gökmen-Polar Y, Escuin D, Walls CD, Soule SE, Wang Y, Sanders KL, Lavallee TM, Wang M, Guenther BD, Giannakakou P, Sledge GW.
    Cancer Res; 2005 Oct 15; 65(20):9406-14. PubMed ID: 16230404
    [Abstract] [Full Text] [Related]

  • 13. Paclitaxel selects for mutant or pseudo-null p53 in drug resistance associated with tubulin mutations in human cancer.
    Giannakakou P, Poy G, Zhan Z, Knutsen T, Blagosklonny MV, Fojo T.
    Oncogene; 2000 Jun 22; 19(27):3078-85. PubMed ID: 10871860
    [Abstract] [Full Text] [Related]

  • 14. Modulation of endogenous beta-tubulin isotype expression as a result of human beta(III)cDNA transfection into prostate carcinoma cells.
    Ranganathan S, McCauley RA, Dexter DW, Hudes GR.
    Br J Cancer; 2001 Sep 01; 85(5):735-40. PubMed ID: 11531260
    [Abstract] [Full Text] [Related]

  • 15. Estramustine depolymerizes microtubules by binding to tubulin.
    Dahllöf B, Billström A, Cabral F, Hartley-Asp B.
    Cancer Res; 1993 Oct 01; 53(19):4573-81. PubMed ID: 8402630
    [Abstract] [Full Text] [Related]

  • 16. Differential assembly kinetics of alpha-tubulin isoforms in the presence of paclitaxel.
    Banerjee A, Kasmala LT.
    Biochem Biophys Res Commun; 1998 Apr 17; 245(2):349-51. PubMed ID: 9571153
    [Abstract] [Full Text] [Related]

  • 17. Heightened sensitivity to paclitaxel in Class IVa beta-tubulin-transfected cells is lost as expression increases.
    Yang H, Cabral F.
    J Biol Chem; 2007 Sep 14; 282(37):27058-27066. PubMed ID: 17627938
    [Abstract] [Full Text] [Related]

  • 18. Human mutations that confer paclitaxel resistance.
    Yin S, Bhattacharya R, Cabral F.
    Mol Cancer Ther; 2010 Feb 14; 9(2):327-35. PubMed ID: 20103599
    [Abstract] [Full Text] [Related]

  • 19. A beta-tubulin leucine cluster involved in microtubule assembly and paclitaxel resistance.
    Gonzalez-Garay ML, Chang L, Blade K, Menick DR, Cabral F.
    J Biol Chem; 1999 Aug 20; 274(34):23875-82. PubMed ID: 10446152
    [Abstract] [Full Text] [Related]

  • 20. Mutagenesis of beta-tubulin cysteine residues in Saccharomyces cerevisiae: mutation of cysteine 354 results in cold-stable microtubules.
    Gupta ML, Bode CJ, Dougherty CA, Marquez RT, Himes RH.
    Cell Motil Cytoskeleton; 2001 Jun 20; 49(2):67-77. PubMed ID: 11443737
    [Abstract] [Full Text] [Related]

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