These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

132 related items for PubMed ID: 15261274

  • 1. Identification of [(naphthalene-1-carbonyl)-amino]-acetic acid derivatives as nonnucleoside inhibitors of HCV NS5B RNA dependent RNA polymerase.
    Gopalsamy A, Lim K, Ellingboe JW, Krishnamurthy G, Orlowski M, Feld B, van Zeijl M, Howe AY.
    Bioorg Med Chem Lett; 2004 Aug 16; 14(16):4221-4. PubMed ID: 15261274
    [Abstract] [Full Text] [Related]

  • 2.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 3. Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery and preliminary SAR of benzimidazole derivatives.
    Beaulieu PL, Bös M, Bousquet Y, Fazal G, Gauthier J, Gillard J, Goulet S, LaPlante S, Poupart MA, Lefebvre S, McKercher G, Pellerin C, Austel V, Kukolj G.
    Bioorg Med Chem Lett; 2004 Jan 05; 14(1):119-24. PubMed ID: 14684311
    [Abstract] [Full Text] [Related]

  • 4. 3-Hydroxyisoquinolines as inhibitors of HCV NS5b RNA-dependent RNA polymerase.
    Hendricks RT, Spencer SR, Blake JF, Fell JB, Fischer JP, Stengel PJ, Leveque VJ, Lepogam S, Rajyaguru S, Najera I, Josey JA, Swallow S.
    Bioorg Med Chem Lett; 2009 Jan 15; 19(2):410-4. PubMed ID: 19070486
    [Abstract] [Full Text] [Related]

  • 5. Further SAR studies on novel small molecule inhibitors of the hepatitis C (HCV) NS5B polymerase.
    Reddy TJ, Chan L, Turcotte N, Proulx M, Pereira OZ, Das SK, Siddiqui A, Wang W, Poisson C, Yannopoulos CG, Bilimoria D, L'Heureux L, Alaoui HM, Nguyen-Ba N.
    Bioorg Med Chem Lett; 2003 Oct 06; 13(19):3341-4. PubMed ID: 12951122
    [Abstract] [Full Text] [Related]

  • 6. Structure-activity relationship (SAR) studies of quinoxalines as novel HCV NS5B RNA-dependent RNA polymerase inhibitors.
    Rong F, Chow S, Yan S, Larson G, Hong Z, Wu J.
    Bioorg Med Chem Lett; 2007 Mar 15; 17(6):1663-6. PubMed ID: 17258458
    [Abstract] [Full Text] [Related]

  • 7. Specific inhibitors of HCV polymerase identified using an NS5B with lower affinity for template/primer substrate.
    McKercher G, Beaulieu PL, Lamarre D, LaPlante S, Lefebvre S, Pellerin C, Thauvette L, Kukolj G.
    Nucleic Acids Res; 2004 Mar 15; 32(2):422-31. PubMed ID: 14739234
    [Abstract] [Full Text] [Related]

  • 8.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 9. Novel nonnucleoside inhibitor of hepatitis C virus RNA-dependent RNA polymerase.
    Howe AY, Bloom J, Baldick CJ, Benetatos CA, Cheng H, Christensen JS, Chunduru SK, Coburn GA, Feld B, Gopalsamy A, Gorczyca WP, Herrmann S, Johann S, Jiang X, Kimberland ML, Krisnamurthy G, Olson M, Orlowski M, Swanberg S, Thompson I, Thorn M, Del Vecchio A, Young DC, van Zeijl M, Ellingboe JW, Upeslacis J, Collett M, Mansour TS, O'Connell JF.
    Antimicrob Agents Chemother; 2004 Dec 15; 48(12):4813-21. PubMed ID: 15561861
    [Abstract] [Full Text] [Related]

  • 10. Structure-based design of a benzodiazepine scaffold yields a potent allosteric inhibitor of hepatitis C NS5B RNA polymerase.
    Vandyck K, Cummings MD, Nyanguile O, Boutton CW, Vendeville S, McGowan D, Devogelaere B, Amssoms K, Last S, Rombauts K, Tahri A, Lory P, Hu L, Beauchamp DA, Simmen K, Raboisson P.
    J Med Chem; 2009 Jul 23; 52(14):4099-102. PubMed ID: 19507864
    [Abstract] [Full Text] [Related]

  • 11. Tetrahydrobenzothiophene inhibitors of hepatitis C virus NS5B polymerase.
    Laporte MG, Lessen TA, Leister L, Cebzanov D, Amparo E, Faust C, Ortlip D, Bailey TR, Nitz TJ, Chunduru SK, Young DC, Burns CJ.
    Bioorg Med Chem Lett; 2006 Jan 01; 16(1):100-3. PubMed ID: 16260131
    [Abstract] [Full Text] [Related]

  • 12. Inhibitors of HCV NS5B polymerase. Part 2: Evaluation of the northern region of (2Z)-2-benzoylamino-3-(4-phenoxy-phenyl)-acrylic acid.
    Pfefferkorn JA, Nugent R, Gross RJ, Greene M, Mitchell MA, Reding MT, Funk LA, Anderson R, Wells PA, Shelly JA, Anstadt R, Finzel BC, Harris MS, Kilkuskie RE, Kopta LA, Schwende FJ.
    Bioorg Med Chem Lett; 2005 Jun 02; 15(11):2812-8. PubMed ID: 15911260
    [Abstract] [Full Text] [Related]

  • 13. Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of N-1-benzyl and N-1-[3-methylbutyl]-4-hydroxy-1,8-naphthyridon-3-yl benzothiadiazine analogs containing substituents on the aromatic ring.
    Rockway TW, Zhang R, Liu D, Betebenner DA, McDaniel KF, Pratt JK, Beno D, Montgomery D, Jiang WW, Masse S, Kati WM, Middleton T, Molla A, Maring CJ, Kempf DJ.
    Bioorg Med Chem Lett; 2006 Jul 15; 16(14):3833-8. PubMed ID: 16650984
    [Abstract] [Full Text] [Related]

  • 14. Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery of benzimidazole 5-carboxylic amide derivatives with low-nanomolar potency.
    Beaulieu PL, Bös M, Bousquet Y, DeRoy P, Fazal G, Gauthier J, Gillard J, Goulet S, McKercher G, Poupart MA, Valois S, Kukolj G.
    Bioorg Med Chem Lett; 2004 Feb 23; 14(4):967-71. PubMed ID: 15013003
    [Abstract] [Full Text] [Related]

  • 15. 1,5-benzodiazepines, a novel class of hepatitis C virus polymerase nonnucleoside inhibitors.
    Nyanguile O, Pauwels F, Van den Broeck W, Boutton CW, Quirynen L, Ivens T, van der Helm L, Vandercruyssen G, Mostmans W, Delouvroy F, Dehertogh P, Cummings MD, Bonfanti JF, Simmen KA, Raboisson P.
    Antimicrob Agents Chemother; 2008 Dec 23; 52(12):4420-31. PubMed ID: 18852280
    [Abstract] [Full Text] [Related]

  • 16. Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of N-1-heteroalkyl-4-hydroxyquinolon-3-yl-benzothiadiazines.
    Pratt JK, Donner P, McDaniel KF, Maring CJ, Kati WM, Mo H, Middleton T, Liu Y, Ng T, Xie Q, Zhang R, Montgomery D, Molla A, Kempf DJ, Kohlbrenner W.
    Bioorg Med Chem Lett; 2005 Mar 15; 15(6):1577-82. PubMed ID: 15745800
    [Abstract] [Full Text] [Related]

  • 17. Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: Sulfonamides.
    Chan L, Das SK, Reddy TJ, Poisson C, Proulx M, Pereira O, Courchesne M, Roy C, Wang W, Siddiqui A, Yannopoulos CG, Nguyen-Ba N, Labrecque D, Bethell R, Hamel M, Courtemanche-Asselin P, L'Heureux L, David M, Nicolas O, Brunette S, Bilimoria D, Bédard J.
    Bioorg Med Chem Lett; 2004 Feb 09; 14(3):793-6. PubMed ID: 14741291
    [Abstract] [Full Text] [Related]

  • 18. Discovery of a potent boronic acid derived inhibitor of the HCV RNA-dependent RNA polymerase.
    Maynard A, Crosby RM, Ellis B, Hamatake R, Hong Z, Johns BA, Kahler KM, Koble C, Leivers A, Leivers MR, Mathis A, Peat AJ, Pouliot JJ, Roberts CD, Samano V, Schmidt RM, Smith GK, Spaltenstein A, Stewart EL, Thommes P, Turner EM, Voitenleitner C, Walker JT, Waitt G, Weatherhead J, Weaver K, Williams S, Wright L, Xiong ZZ, Haigh D, Shotwell JB.
    J Med Chem; 2014 Mar 13; 57(5):1902-13. PubMed ID: 23672667
    [Abstract] [Full Text] [Related]

  • 19. Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda(6)-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 2: Variation of the 2- and 6-pyridazinone substituents.
    Zhou Y, Li LS, Dragovich PS, Murphy DE, Tran CV, Ruebsam F, Webber SE, Shah AM, Tsan M, Averill A, Showalter RE, Patel R, Han Q, Zhao Q, Hermann T, Kissinger CR, Lebrun L, Sergeeva MV.
    Bioorg Med Chem Lett; 2008 Feb 15; 18(4):1419-24. PubMed ID: 18226901
    [Abstract] [Full Text] [Related]

  • 20. Discovery of alpha,gamma-diketo acids as potent selective and reversible inhibitors of hepatitis C virus NS5b RNA-dependent RNA polymerase.
    Summa V, Petrocchi A, Pace P, Matassa VG, De Francesco R, Altamura S, Tomei L, Koch U, Neuner P.
    J Med Chem; 2004 Jan 01; 47(1):14-7. PubMed ID: 14695815
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 7.