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215 related items for PubMed ID: 15262269

  • 1. Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1.
    Szapacs ME, Numis AL, Andrews AM.
    Neurobiol Dis; 2004 Aug; 16(3):572-80. PubMed ID: 15262269
    [Abstract] [Full Text] [Related]

  • 2. The neurotoxin 2'-NH2-MPTP degenerates serotonin axons and evokes increases in hippocampal BDNF.
    Luellen BA, Szapacs ME, Materese CK, Andrews AM.
    Neuropharmacology; 2006 Mar; 50(3):297-308. PubMed ID: 16288930
    [Abstract] [Full Text] [Related]

  • 3. 2'-NH2-MPTP in Swiss Webster mice: evidence for long-term (6-month) depletions in cortical and hippocampal serotonin and norepinephrine, differential protection by selective uptake inhibitors or clorgyline and functional changes in central serotonin neurotransmission.
    Andrews AM, Murphy DL.
    J Pharmacol Exp Ther; 1993 Dec; 267(3):1432-9. PubMed ID: 8263805
    [Abstract] [Full Text] [Related]

  • 4. Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway.
    Jaffar S, Counts SE, Ma SY, Dadko E, Gordon MN, Morgan D, Mufson EJ.
    Exp Neurol; 2001 Aug; 170(2):227-43. PubMed ID: 11476589
    [Abstract] [Full Text] [Related]

  • 5. Reduced brain-derived neurotrophic factor is associated with a loss of serotonergic innervation in the hippocampus of aging mice.
    Luellen BA, Bianco LE, Schneider LM, Andrews AM.
    Genes Brain Behav; 2007 Jul; 6(5):482-90. PubMed ID: 17156118
    [Abstract] [Full Text] [Related]

  • 6. Neuronal and astroglial responses to the serotonin and norepinephrine neurotoxin: 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine.
    Luellen BA, Miller DB, Chisnell AC, Murphy DL, O'Callaghan JP, Andrews AM.
    J Pharmacol Exp Ther; 2003 Dec; 307(3):923-31. PubMed ID: 14561848
    [Abstract] [Full Text] [Related]

  • 7. APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1.
    Jankowsky JL, Slunt HH, Gonzales V, Jenkins NA, Copeland NG, Borchelt DR.
    Neurobiol Aging; 2004 Aug; 25(7):885-92. PubMed ID: 15212842
    [Abstract] [Full Text] [Related]

  • 8. Behavioral and serotonergic consequences of decreasing or increasing hippocampus brain-derived neurotrophic factor protein levels in mice.
    Deltheil T, Guiard BP, Cerdan J, David DJ, Tanaka KF, Repérant C, Guilloux JP, Coudoré F, Hen R, Gardier AM.
    Neuropharmacology; 2008 Nov; 55(6):1006-14. PubMed ID: 18761360
    [Abstract] [Full Text] [Related]

  • 9. Transgenic mice with high levels of superoxide dismutase activity are protected from the neurotoxic effects of 2'-NH2-MPTP on serotonergic and noradrenergic nerve terminals.
    Andrews AM, Ladenheim B, Epstein CJ, Cadet JL, Murphy DL.
    Mol Pharmacol; 1996 Dec; 50(6):1511-9. PubMed ID: 8967972
    [Abstract] [Full Text] [Related]

  • 10. Hippocampal A beta 42 levels correlate with spatial memory deficit in APP and PS1 double transgenic mice.
    Puoliväli J, Wang J, Heikkinen T, Heikkilä M, Tapiola T, van Groen T, Tanila H.
    Neurobiol Dis; 2002 Apr; 9(3):339-47. PubMed ID: 11950278
    [Abstract] [Full Text] [Related]

  • 11. Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits.
    Jardanhazi-Kurutz D, Kummer MP, Terwel D, Vogel K, Dyrks T, Thiele A, Heneka MT.
    Neurochem Int; 2010 Nov; 57(4):375-82. PubMed ID: 20144675
    [Abstract] [Full Text] [Related]

  • 12. Deposition of mouse amyloid beta in human APP/PS1 double and single AD model transgenic mice.
    van Groen T, Kiliaan AJ, Kadish I.
    Neurobiol Dis; 2006 Sep; 23(3):653-62. PubMed ID: 16829076
    [Abstract] [Full Text] [Related]

  • 13. Reelin-immunoreactivity in the hippocampal formation of 9-month-old wildtype mouse: effects of APP/PS1 genotype and ovariectomy.
    Miettinen R, Riedel A, Kalesnykas G, Kettunen HP, Puoliväli J, Soininen H, Arendt T.
    J Chem Neuroanat; 2005 Oct; 30(2-3):105-18. PubMed ID: 16081247
    [Abstract] [Full Text] [Related]

  • 14. 2'-NH(2)-MPTP [1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine] depletes serotonin and norepinephrine in rats: a comparison with 2'-CH(3)-MPTP [1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine].
    Unger EL, Mazzola-Pomietto P, Murphy DL, Andrews AM.
    J Pharmacol Exp Ther; 2002 Nov; 303(2):527-33. PubMed ID: 12388632
    [Abstract] [Full Text] [Related]

  • 15. Early dysregulation of hippocampal proteins in transgenic rats with Alzheimer's disease-linked mutations in amyloid precursor protein and presenilin 1.
    Vercauteren FG, Clerens S, Roy L, Hamel N, Arckens L, Vandesande F, Alhonen L, Janne J, Szyf M, Cuello AC.
    Brain Res Mol Brain Res; 2004 Dec 20; 132(2):241-59. PubMed ID: 15582162
    [Abstract] [Full Text] [Related]

  • 16. Exploring the relationship between serotonin and brain-derived neurotrophic factor: analysis of BDNF protein and extraneuronal 5-HT in mice with reduced serotonin transporter or BDNF expression.
    Szapacs ME, Mathews TA, Tessarollo L, Ernest Lyons W, Mamounas LA, Andrews AM.
    J Neurosci Methods; 2004 Dec 30; 140(1-2):81-92. PubMed ID: 15589338
    [Abstract] [Full Text] [Related]

  • 17. Mutations in amyloid precursor protein and presenilin-1 genes increase the basal oxidative stress in murine neuronal cells and lead to increased sensitivity to oxidative stress mediated by amyloid beta-peptide (1-42), HO and kainic acid: implications for Alzheimer's disease.
    Mohmmad Abdul H, Sultana R, Keller JN, St Clair DK, Markesbery WR, Butterfield DA.
    J Neurochem; 2006 Mar 30; 96(5):1322-35. PubMed ID: 16478525
    [Abstract] [Full Text] [Related]

  • 18. Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities.
    Savonenko A, Xu GM, Melnikova T, Morton JL, Gonzales V, Wong MP, Price DL, Tang F, Markowska AL, Borchelt DR.
    Neurobiol Dis; 2005 Apr 30; 18(3):602-17. PubMed ID: 15755686
    [Abstract] [Full Text] [Related]

  • 19. Increase in presenilin 1 (PS1) levels in senescence-accelerated mice (SAMP8) may indirectly impair memory by affecting amyloid precursor protein (APP) processing.
    Kumar VB, Franko M, Banks WA, Kasinadhuni P, Farr SA, Vyas K, Choudhuri V, Morley JE.
    J Exp Biol; 2009 Feb 30; 212(Pt 4):494-8. PubMed ID: 19181896
    [Abstract] [Full Text] [Related]

  • 20. Altered levels and distribution of IGF-II/M6P receptor and lysosomal enzymes in mutant APP and APP + PS1 transgenic mouse brains.
    Amritraj A, Hawkes C, Phinney AL, Mount HT, Scott CD, Westaway D, Kar S.
    Neurobiol Aging; 2009 Jan 30; 30(1):54-70. PubMed ID: 17561313
    [Abstract] [Full Text] [Related]

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