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489 related items for PubMed ID: 15277221

  • 1. Interleukin-6/soluble interleukin-6 receptor signaling attenuates proliferation and invasion, and induces morphological changes of a newly established pleomorphic malignant fibrous histiocytoma cell line.
    Nakanishi H, Yoshioka K, Joyama S, Araki N, Myoui A, Ishiguro S, Ueda T, Yoshikawa H, Itoh K.
    Am J Pathol; 2004 Aug; 165(2):471-80. PubMed ID: 15277221
    [Abstract] [Full Text] [Related]

  • 2. Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo.
    Atreya R, Mudter J, Finotto S, Müllberg J, Jostock T, Wirtz S, Schütz M, Bartsch B, Holtmann M, Becker C, Strand D, Czaja J, Schlaak JF, Lehr HA, Autschbach F, Schürmann G, Nishimoto N, Yoshizaki K, Ito H, Kishimoto T, Galle PR, Rose-John S, Neurath MF.
    Nat Med; 2000 May; 6(5):583-8. PubMed ID: 10802717
    [Abstract] [Full Text] [Related]

  • 3. Directly linked soluble IL-6 receptor-IL-6 fusion protein induces astrocyte differentiation from neuroepithelial cells via activation of STAT3.
    Takizawa T, Yanagisawa M, Ochiai W, Yasukawa K, Ishiguro T, Nakashima K, Taga T.
    Cytokine; 2001 Mar 07; 13(5):272-9. PubMed ID: 11243705
    [Abstract] [Full Text] [Related]

  • 4. Interleukin-6 inhibits cell proliferation in a rat model of hepatocellular carcinoma.
    Moran DM, Mayes N, Koniaris LG, Cahill PA, McKillop IH.
    Liver Int; 2005 Apr 07; 25(2):445-57. PubMed ID: 15780071
    [Abstract] [Full Text] [Related]

  • 5. Prostaglandin E(2) stimulates prostatic intraepithelial neoplasia cell growth through activation of the interleukin-6/GP130/STAT-3 signaling pathway.
    Liu XH, Kirschenbaum A, Lu M, Yao S, Klausner A, Preston C, Holland JF, Levine AC.
    Biochem Biophys Res Commun; 2002 Jan 11; 290(1):249-55. PubMed ID: 11779161
    [Abstract] [Full Text] [Related]

  • 6. Enhancement of gp130-mediated tyrosine phosphorylation of STAT3 and its DNA-binding activity in dexamethasone-treated AIDS-associated Kaposi's sarcoma cells: selective synergy between dexamethasone and gp130-related growth factors in Kaposi's sarcoma cell proliferation.
    Murakami-Mori K, Mori S, Taga T, Kishimoto T, Nakamura S.
    J Immunol; 1997 Jun 01; 158(11):5518-26. PubMed ID: 9164976
    [Abstract] [Full Text] [Related]

  • 7. Role of the IL-6 classic- and trans-signaling pathways in corneal sterile inflammation and wound healing.
    Ebihara N, Matsuda A, Nakamura S, Matsuda H, Murakami A.
    Invest Ophthalmol Vis Sci; 2011 Nov 01; 52(12):8549-57. PubMed ID: 21989726
    [Abstract] [Full Text] [Related]

  • 8. Local blockade of IL-6R signaling induces lung CD4+ T cell apoptosis in a murine model of asthma via regulatory T cells.
    Finotto S, Eigenbrod T, Karwot R, Boross I, Doganci A, Ito H, Nishimoto N, Yoshizaki K, Kishimoto T, Rose-John S, Galle PR, Neurath MF.
    Int Immunol; 2007 Jun 01; 19(6):685-93. PubMed ID: 17496315
    [Abstract] [Full Text] [Related]

  • 9. Signal through gp130 activated by soluble interleukin (IL)-6 receptor (R) and IL-6 or IL-6R/IL-6 fusion protein enhances ex vivo expansion of human peripheral blood-derived hematopoietic progenitors.
    Kimura T, Wang J, Minamiguchi H, Fujiki H, Harada S, Okuda K, Kaneko H, Yokota S, Yasukawa K, Abe T, Sonoda Y.
    Stem Cells; 2000 Jun 01; 18(6):444-52. PubMed ID: 11072033
    [Abstract] [Full Text] [Related]

  • 10. The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury.
    Klein C, Wüstefeld T, Assmus U, Roskams T, Rose-John S, Müller M, Manns MP, Ernst M, Trautwein C.
    J Clin Invest; 2005 Apr 01; 115(4):860-9. PubMed ID: 15761498
    [Abstract] [Full Text] [Related]

  • 11. Combination of interleukin-6 and soluble interleukin-6 receptors induces differentiation and activation of JAK-STAT and MAP kinase pathways in MG-63 human osteoblastic cells.
    Nishimura R, Moriyama K, Yasukawa K, Mundy GR, Yoneda T.
    J Bone Miner Res; 1998 May 01; 13(5):777-85. PubMed ID: 9610741
    [Abstract] [Full Text] [Related]

  • 12. STAT3 is dispensable for maintenance of self-renewal in nonhuman primate embryonic stem cells.
    Sumi T, Fujimoto Y, Nakatsuji N, Suemori H.
    Stem Cells; 2004 May 01; 22(5):861-72. PubMed ID: 15342949
    [Abstract] [Full Text] [Related]

  • 13. Resistance to interleukin 6 in human non-small cell lung carcinoma cell lines: role of receptor components.
    Ganapathi MK, Weizer AK, Borsellino S, Bukowski RM, Ganapathi R, Rice T, Casey G, Kawamura K.
    Cell Growth Differ; 1996 Jul 01; 7(7):923-9. PubMed ID: 8809410
    [Abstract] [Full Text] [Related]

  • 14. Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors.
    Hirano T, Ishihara K, Hibi M.
    Oncogene; 2000 May 15; 19(21):2548-56. PubMed ID: 10851053
    [Abstract] [Full Text] [Related]

  • 15. Soluble mannose 6-phosphate/insulin-like growth factor II (IGF-II) receptor inhibits interleukin-6-type cytokine-dependent proliferation by neutralization of IGF-II.
    Duplomb L, Chaigne-Delalande B, Vusio P, Raher S, Jacques Y, Godard A, Blanchard F.
    Endocrinology; 2003 Dec 15; 144(12):5381-9. PubMed ID: 12959977
    [Abstract] [Full Text] [Related]

  • 16. Shedding of the interleukin-6 (IL-6) receptor (gp80) determines the ability of IL-6 to induce gp130 phosphorylation in human osteoblasts.
    Vermes C, Jacobs JJ, Zhang J, Firneisz G, Roebuck KA, Glant TT.
    J Biol Chem; 2002 May 10; 277(19):16879-87. PubMed ID: 11884403
    [Abstract] [Full Text] [Related]

  • 17. In vivo and in vitro activities of the gp130-stimulating designer cytokine Hyper-IL-6.
    Peters M, Blinn G, Solem F, Fischer M, Meyer zum Büschenfelde KH, Rose-John S.
    J Immunol; 1998 Oct 01; 161(7):3575-81. PubMed ID: 9759879
    [Abstract] [Full Text] [Related]

  • 18. IL-6 transsignaling: the in vivo consequences.
    Jones SA, Richards PJ, Scheller J, Rose-John S.
    J Interferon Cytokine Res; 2005 May 01; 25(5):241-53. PubMed ID: 15871661
    [Abstract] [Full Text] [Related]

  • 19. Major role of the soluble interleukin-6/interleukin-6 receptor complex for the proliferation of interleukin-6-dependent human myeloma cell lines.
    Gaillard JP, Liautard J, Klein B, Brochier J.
    Eur J Immunol; 1997 Dec 01; 27(12):3332-40. PubMed ID: 9464821
    [Abstract] [Full Text] [Related]

  • 20. Reproductive hormone-induced, STAT3-mediated interleukin 6 action in normal and malignant human ovarian surface epithelial cells.
    Syed V, Ulinski G, Mok SC, Ho SM.
    J Natl Cancer Inst; 2002 Apr 17; 94(8):617-29. PubMed ID: 11959895
    [Abstract] [Full Text] [Related]

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