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261 related items for PubMed ID: 15280015

  • 1. Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site.
    Aho TL, Sandholm J, Peltola KJ, Mankonen HP, Lilly M, Koskinen PJ.
    FEBS Lett; 2004 Jul 30; 571(1-3):43-9. PubMed ID: 15280015
    [Abstract] [Full Text] [Related]

  • 2. The PIM-1 serine kinase prolongs survival and inhibits apoptosis-related mitochondrial dysfunction in part through a bcl-2-dependent pathway.
    Lilly M, Sandholm J, Cooper JJ, Koskinen PJ, Kraft A.
    Oncogene; 1999 Jul 08; 18(27):4022-31. PubMed ID: 10435626
    [Abstract] [Full Text] [Related]

  • 3. Phosphatidylinositol 3-kinase (PI-3K)/Akt but not PI-3K/p70 S6 kinase signaling mediates IGF-1-promoted lens epithelial cell survival.
    Chandrasekher G, Sailaja D.
    Invest Ophthalmol Vis Sci; 2004 Oct 08; 45(10):3577-88. PubMed ID: 15452065
    [Abstract] [Full Text] [Related]

  • 4. Serine/threonine kinase Pim-2 promotes liver tumorigenesis induction through mediating survival and preventing apoptosis of liver cell.
    Gong J, Wang J, Ren K, Liu C, Li B, Shi Y.
    J Surg Res; 2009 May 01; 153(1):17-22. PubMed ID: 18675992
    [Abstract] [Full Text] [Related]

  • 5. Pim-3, a proto-oncogene with serine/threonine kinase activity, is aberrantly expressed in human pancreatic cancer and phosphorylates bad to block bad-mediated apoptosis in human pancreatic cancer cell lines.
    Li YY, Popivanova BK, Nagai Y, Ishikura H, Fujii C, Mukaida N.
    Cancer Res; 2006 Jul 01; 66(13):6741-7. PubMed ID: 16818649
    [Abstract] [Full Text] [Related]

  • 6. The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death.
    Yan B, Zemskova M, Holder S, Chin V, Kraft A, Koskinen PJ, Lilly M.
    J Biol Chem; 2003 Nov 14; 278(46):45358-67. PubMed ID: 12954615
    [Abstract] [Full Text] [Related]

  • 7. Constitutively activated FLT3 phosphorylates BAD partially through pim-1.
    Kim KT, Levis M, Small D.
    Br J Haematol; 2006 Sep 14; 134(5):500-9. PubMed ID: 16869825
    [Abstract] [Full Text] [Related]

  • 8. The oncogenic serine/threonine kinase Pim-1 directly phosphorylates and activates the G2/M specific phosphatase Cdc25C.
    Bachmann M, Kosan C, Xing PX, Montenarh M, Hoffmann I, Möröy T.
    Int J Biochem Cell Biol; 2006 Mar 14; 38(3):430-43. PubMed ID: 16356754
    [Abstract] [Full Text] [Related]

  • 9. Pim-1 associates with protein complexes necessary for mitosis.
    Bhattacharya N, Wang Z, Davitt C, McKenzie IF, Xing PX, Magnuson NS.
    Chromosoma; 2002 Jul 14; 111(2):80-95. PubMed ID: 12111331
    [Abstract] [Full Text] [Related]

  • 10. Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway.
    Yano S, Tokumitsu H, Soderling TR.
    Nature; 1998 Dec 10; 396(6711):584-7. PubMed ID: 9859994
    [Abstract] [Full Text] [Related]

  • 11. The 44 kDa Pim-1 kinase directly interacts with tyrosine kinase Etk/BMX and protects human prostate cancer cells from apoptosis induced by chemotherapeutic drugs.
    Xie Y, Xu K, Dai B, Guo Z, Jiang T, Chen H, Qiu Y.
    Oncogene; 2006 Jan 05; 25(1):70-8. PubMed ID: 16186805
    [Abstract] [Full Text] [Related]

  • 12. Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL.
    Macdonald A, Campbell DG, Toth R, McLauchlan H, Hastie CJ, Arthur JS.
    BMC Cell Biol; 2006 Jan 10; 7():1. PubMed ID: 16403219
    [Abstract] [Full Text] [Related]

  • 13. Rac1 inhibits apoptosis in human lymphoma cells by stimulating Bad phosphorylation on Ser-75.
    Zhang B, Zhang Y, Shacter E.
    Mol Cell Biol; 2004 Jul 10; 24(14):6205-14. PubMed ID: 15226424
    [Abstract] [Full Text] [Related]

  • 14. Protein kinase CK2 phosphorylates BAD at threonine-117.
    Klumpp S, Mäurer A, Zhu Y, Aichele D, Pinna LA, Krieglstein J.
    Neurochem Int; 2004 Oct 10; 45(5):747-52. PubMed ID: 15234118
    [Abstract] [Full Text] [Related]

  • 15. Pim-1 kinase stimulates c-Myc-mediated death signaling upstream of caspase-3 (CPP32)-like protease activation.
    Mochizuki T, Kitanaka C, Noguchi K, Sugiyama A, Kagaya S, Chi S, Asai A, Kuchino Y.
    Oncogene; 1997 Sep 18; 15(12):1471-80. PubMed ID: 9333023
    [Abstract] [Full Text] [Related]

  • 16. Enforced expression of the Mr 33,000 Pim-1 kinase enhances factor-independent survival and inhibits apoptosis in murine myeloid cells.
    Lilly M, Kraft A.
    Cancer Res; 1997 Dec 01; 57(23):5348-55. PubMed ID: 9393759
    [Abstract] [Full Text] [Related]

  • 17. Phosphorylation of BAD at Ser-128 during mitosis and paclitaxel-induced apoptosis.
    Berndtsson M, Konishi Y, Bonni A, Hägg M, Shoshan M, Linder S, Havelka AM.
    FEBS Lett; 2005 Jun 06; 579(14):3090-4. PubMed ID: 15907327
    [Abstract] [Full Text] [Related]

  • 18. A point mutation in the putative ATP binding site of the pseudorabies virus US3 protein kinase prevents Bad phosphorylation and cell survival following apoptosis induction.
    Deruelle M, Geenen K, Nauwynck HJ, Favoreel HW.
    Virus Res; 2007 Sep 06; 128(1-2):65-70. PubMed ID: 17499381
    [Abstract] [Full Text] [Related]

  • 19. Pim-1 kinase protects hematopoietic FDC cells from genotoxin-induced death.
    Pircher TJ, Zhao S, Geiger JN, Joneja B, Wojchowski DM.
    Oncogene; 2000 Jul 27; 19(32):3684-92. PubMed ID: 10951575
    [Abstract] [Full Text] [Related]

  • 20. The apoptotic v-cyclin-CDK6 complex phosphorylates and inactivates Bcl-2.
    Ojala PM, Yamamoto K, Castaños-Vélez E, Biberfeld P, Korsmeyer SJ, Mäkelä TP.
    Nat Cell Biol; 2000 Nov 27; 2(11):819-25. PubMed ID: 11056537
    [Abstract] [Full Text] [Related]

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