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150 related items for PubMed ID: 15284538

  • 1. A substrate specific functional polymorphism of human gamma-glutamyl hydrolase alters catalytic activity and methotrexate polyglutamate accumulation in acute lymphoblastic leukaemia cells.
    Cheng Q, Wu B, Kager L, Panetta JC, Zheng J, Pui CH, Relling MV, Evans WE.
    Pharmacogenetics; 2004 Aug; 14(8):557-67. PubMed ID: 15284538
    [Abstract] [Full Text] [Related]

  • 2. Methotrexate intracellular disposition in acute lymphoblastic leukemia: a mathematical model of gamma-glutamyl hydrolase activity.
    Panetta JC, Wall A, Pui CH, Relling MV, Evans WE.
    Clin Cancer Res; 2002 Jul; 8(7):2423-9. PubMed ID: 12114448
    [Abstract] [Full Text] [Related]

  • 3. Do SNPs in folate pharmacokinetic pathway alter levels of intracellular methotrexate polyglutamates and affect response? A prospective study in Indian patients.
    Sandhu A, Ahmad S, Kaur J, Bhatnagar A, Dhawan V, Dhir V.
    Clin Rheumatol; 2018 Dec; 37(12):3221-3228. PubMed ID: 30022368
    [Abstract] [Full Text] [Related]

  • 4. Epigenetic regulation of human gamma-glutamyl hydrolase activity in acute lymphoblastic leukemia cells.
    Cheng Q, Cheng C, Crews KR, Ribeiro RC, Pui CH, Relling MV, Evans WE.
    Am J Hum Genet; 2006 Aug; 79(2):264-74. PubMed ID: 16826517
    [Abstract] [Full Text] [Related]

  • 5. Exploratory analysis of four polymorphisms in human GGH and FPGS genes and their effect in methotrexate-treated rheumatoid arthritis patients.
    van der Straaten RJ, Wessels JA, de Vries-Bouwstra JK, Goekoop-Ruiterman YP, Allaart CF, Bogaartz J, Tiller M, Huizinga TW, Guchelaar HJ.
    Pharmacogenomics; 2007 Feb; 8(2):141-50. PubMed ID: 17286537
    [Abstract] [Full Text] [Related]

  • 6. gamma-Glutamyl hydrolase and folylpolyglutamate synthetase activities predict polyglutamylation of methotrexate in acute leukemias.
    Longo GS, Gorlick R, Tong WP, Lin S, Steinherz P, Bertino JR.
    Oncol Res; 1997 Feb; 9(5):259-63. PubMed ID: 9306433
    [Abstract] [Full Text] [Related]

  • 7. Genetic polymorphism of γ-glutamyl hydrolase in Chinese acute leukemia children and identification of a novel double nonsynonymous mutation.
    Chen X, Wen F, Yue L, Li C.
    Pediatr Hematol Oncol; 2012 May; 29(4):303-12. PubMed ID: 22568793
    [Abstract] [Full Text] [Related]

  • 8. Therapeutic responses in childhood acute lymphoblastic leukemia (ALL) and haplotypes of gamma glutamyl hydrolase (GGH) gene.
    Garcia-Bournissen F, Moghrabi A, Krajinovic M.
    Leuk Res; 2007 Jul; 31(7):1023-5. PubMed ID: 16999998
    [No Abstract] [Full Text] [Related]

  • 9. A mathematical model of in vivo methotrexate accumulation in acute lymphoblastic leukemia.
    Panetta JC, Yanishevski Y, Pui CH, Sandlund JT, Rubnitz J, Rivera GK, Ribeiro R, Evans WE, Relling MV.
    Cancer Chemother Pharmacol; 2002 Nov; 50(5):419-28. PubMed ID: 12439601
    [Abstract] [Full Text] [Related]

  • 10. Influence of genetic polymorphisms of FPGS, GGH, and MTHFR on serum methotrexate levels in Chinese children with acute lymphoblastic leukemia.
    Wang SM, Sun LL, Zeng WX, Wu WS, Zhang GL.
    Cancer Chemother Pharmacol; 2014 Aug; 74(2):283-9. PubMed ID: 24908438
    [Abstract] [Full Text] [Related]

  • 11. [Separation of methotrexate-polyglutamates by capillary electrophoresis and its application to the measurement of gamma-glutamyl hydrolase activity in human leukemia cells in culture].
    Takemura Y, Kobayashi H, Sekiguchi S.
    Rinsho Byori; 1996 Jan; 44(1):51-6. PubMed ID: 8691640
    [Abstract] [Full Text] [Related]

  • 12. Genotyping of single nucleotide polymorphism in γ-glutamyl hydrolase gene by capillary electrophoresis.
    Cheng HL, Chiou SS, Liao YM, Chen YL, Wu SM.
    Electrophoresis; 2011 Aug; 32(15):2021-7. PubMed ID: 21538980
    [Abstract] [Full Text] [Related]

  • 13. Contribution of common polymorphisms in reduced folate carrier and gamma-glutamylhydrolase to methotrexate polyglutamate levels in patients with rheumatoid arthritis.
    Dervieux T, Kremer J, Lein DO, Capps R, Barham R, Meyer G, Smith K, Caldwell J, Furst DE.
    Pharmacogenetics; 2004 Nov; 14(11):733-9. PubMed ID: 15564880
    [Abstract] [Full Text] [Related]

  • 14. Association between polymorphisms of dihydrofolate reductase and gamma glutamyl hydrolase genes and toxicity of high dose methotrexate in children with acute lymphoblastic leukemia.
    Koomdee N, Hongeng S, Apibal S, Pakakasama S.
    Asian Pac J Cancer Prev; 2012 Nov; 13(7):3461-4. PubMed ID: 22994778
    [Abstract] [Full Text] [Related]

  • 15. Reduced folate carrier expression in acute lymphoblastic leukemia: a mechanism for ploidy but not lineage differences in methotrexate accumulation.
    Belkov VM, Krynetski EY, Schuetz JD, Yanishevski Y, Masson E, Mathew S, Raimondi S, Pui CH, Relling MV, Evans WE.
    Blood; 1999 Mar 01; 93(5):1643-50. PubMed ID: 10029593
    [Abstract] [Full Text] [Related]

  • 16. Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia.
    Synold TW, Relling MV, Boyett JM, Rivera GK, Sandlund JT, Mahmoud H, Crist WM, Pui CH, Evans WE.
    J Clin Invest; 1994 Nov 01; 94(5):1996-2001. PubMed ID: 7525652
    [Abstract] [Full Text] [Related]

  • 17. Identification of single nucleotide polymorphisms in the human gamma-glutamyl hydrolase gene and characterization of promoter polymorphisms.
    Chave KJ, Ryan TJ, Chmura SE, Galivan J.
    Gene; 2003 Nov 13; 319():167-75. PubMed ID: 14597182
    [Abstract] [Full Text] [Related]

  • 18. Capillary electrophoresis of methotrexate polyglutamates and its application in evaluation of gamma-glutamyl hydrolase activity.
    Waltham MC, Lin S, Li WW, Göker E, Gritsman H, Tong WP, Bertino JR.
    J Chromatogr B Biomed Sci Appl; 1997 Feb 21; 689(2):387-92. PubMed ID: 9080326
    [Abstract] [Full Text] [Related]

  • 19. Accumulation of high levels of methotrexate polyglutamates in lymphoblasts from children with hyperdiploid (greater than 50 chromosomes) B-lineage acute lymphoblastic leukemia: a Pediatric Oncology Group study.
    Whitehead VM, Vuchich MJ, Lauer SJ, Mahoney D, Carroll AJ, Shuster JJ, Esseltine DW, Payment C, Look AT, Akabutu J.
    Blood; 1992 Sep 01; 80(5):1316-23. PubMed ID: 1381244
    [Abstract] [Full Text] [Related]

  • 20. Effects of overexpression of gamma-Glutamyl hydrolase on methotrexate metabolism and resistance.
    Cole PD, Kamen BA, Gorlick R, Banerjee D, Smith AK, Magill E, Bertino JR.
    Cancer Res; 2001 Jun 01; 61(11):4599-604. PubMed ID: 11389096
    [Abstract] [Full Text] [Related]

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