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236 related items for PubMed ID: 15292249

  • 1. In rat hepatocytes glucagon increases mammalian target of rapamycin phosphorylation on serine 2448 but antagonizes the phosphorylation of its downstream targets induced by insulin and amino acids.
    Mothe-Satney I, Gautier N, Hinault C, Lawrence JC, Van Obberghen E.
    J Biol Chem; 2004 Oct 08; 279(41):42628-37. PubMed ID: 15292249
    [Abstract] [Full Text] [Related]

  • 2. Attenuation of mammalian target of rapamycin activity by increased cAMP in 3T3-L1 adipocytes.
    Scott PH, Lawrence JC.
    J Biol Chem; 1998 Dec 18; 273(51):34496-501. PubMed ID: 9852118
    [Abstract] [Full Text] [Related]

  • 3. Assessment of cell-signaling pathways in the regulation of mammalian target of rapamycin (mTOR) by amino acids in rat adipocytes.
    Pham PT, Heydrick SJ, Fox HL, Kimball SR, Jefferson LS, Lynch CJ.
    J Cell Biochem; 2000 Sep 07; 79(3):427-41. PubMed ID: 10972980
    [Abstract] [Full Text] [Related]

  • 4. Glucagon represses signaling through the mammalian target of rapamycin in rat liver by activating AMP-activated protein kinase.
    Kimball SR, Siegfried BA, Jefferson LS.
    J Biol Chem; 2004 Dec 24; 279(52):54103-9. PubMed ID: 15494402
    [Abstract] [Full Text] [Related]

  • 5. Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin.
    Takano A, Usui I, Haruta T, Kawahara J, Uno T, Iwata M, Kobayashi M.
    Mol Cell Biol; 2001 Aug 24; 21(15):5050-62. PubMed ID: 11438661
    [Abstract] [Full Text] [Related]

  • 6. Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes.
    Tremblay F, Gagnon A, Veilleux A, Sorisky A, Marette A.
    Endocrinology; 2005 Mar 24; 146(3):1328-37. PubMed ID: 15576463
    [Abstract] [Full Text] [Related]

  • 7. Prolactin activates mammalian target-of-rapamycin through phosphatidylinositol 3-kinase and stimulates phosphorylation of p70S6K and 4E-binding protein-1 in lymphoma cells.
    Bishop JD, Nien WL, Dauphinee SM, Too CK.
    J Endocrinol; 2006 Aug 24; 190(2):307-12. PubMed ID: 16899564
    [Abstract] [Full Text] [Related]

  • 8. Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism.
    Hara K, Yonezawa K, Weng QP, Kozlowski MT, Belham C, Avruch J.
    J Biol Chem; 1998 Jun 05; 273(23):14484-94. PubMed ID: 9603962
    [Abstract] [Full Text] [Related]

  • 9. Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins.
    Wang X, Beugnet A, Murakami M, Yamanaka S, Proud CG.
    Mol Cell Biol; 2005 Apr 05; 25(7):2558-72. PubMed ID: 15767663
    [Abstract] [Full Text] [Related]

  • 10. Insulin and IGF-I stimulate the formation of the eukaryotic initiation factor 4F complex and protein synthesis in C2C12 myotubes independent of availability of external amino acids.
    Shen WH, Boyle DW, Wisniowski P, Bade A, Liechty EA.
    J Endocrinol; 2005 May 05; 185(2):275-89. PubMed ID: 15845920
    [Abstract] [Full Text] [Related]

  • 11. A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells.
    Sekulić A, Hudson CC, Homme JL, Yin P, Otterness DM, Karnitz LM, Abraham RT.
    Cancer Res; 2000 Jul 01; 60(13):3504-13. PubMed ID: 10910062
    [Abstract] [Full Text] [Related]

  • 12. Luteinizing hormone stimulates mammalian target of rapamycin signaling in bovine luteal cells via pathways independent of AKT and mitogen-activated protein kinase: modulation of glycogen synthase kinase 3 and AMP-activated protein kinase.
    Hou X, Arvisais EW, Davis JS.
    Endocrinology; 2010 Jun 01; 151(6):2846-57. PubMed ID: 20351317
    [Abstract] [Full Text] [Related]

  • 13. Regulation of hepatic insulin-like growth factor-binding protein-1 gene expression by insulin: central role for mammalian target of rapamycin independent of forkhead box O proteins.
    Mounier C, Dumas V, Posner BI.
    Endocrinology; 2006 May 01; 147(5):2383-91. PubMed ID: 16455781
    [Abstract] [Full Text] [Related]

  • 14. Activation of mRNA translation in rat cardiac myocytes by insulin involves multiple rapamycin-sensitive steps.
    Wang L, Wang X, Proud CG.
    Am J Physiol Heart Circ Physiol; 2000 Apr 01; 278(4):H1056-68. PubMed ID: 10749698
    [Abstract] [Full Text] [Related]

  • 15. Amino acids and leucine allow insulin activation of the PKB/mTOR pathway in normal adipocytes treated with wortmannin and in adipocytes from db/db mice.
    Hinault C, Mothe-Satney I, Gautier N, Lawrence JC, Van Obberghen E.
    FASEB J; 2004 Dec 01; 18(15):1894-6. PubMed ID: 15479767
    [Abstract] [Full Text] [Related]

  • 16. Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway.
    Scott PH, Brunn GJ, Kohn AD, Roth RA, Lawrence JC.
    Proc Natl Acad Sci U S A; 1998 Jun 23; 95(13):7772-7. PubMed ID: 9636226
    [Abstract] [Full Text] [Related]

  • 17. The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses.
    Smith EM, Finn SG, Tee AR, Browne GJ, Proud CG.
    J Biol Chem; 2005 May 13; 280(19):18717-27. PubMed ID: 15772076
    [Abstract] [Full Text] [Related]

  • 18. 4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway.
    Gingras AC, Kennedy SG, O'Leary MA, Sonenberg N, Hay N.
    Genes Dev; 1998 Feb 15; 12(4):502-13. PubMed ID: 9472019
    [Abstract] [Full Text] [Related]

  • 19. Chronic paraplegia-induced muscle atrophy downregulates the mTOR/S6K1 signaling pathway.
    Dreyer HC, Glynn EL, Lujan HL, Fry CS, DiCarlo SE, Rasmussen BB.
    J Appl Physiol (1985); 2008 Jan 15; 104(1):27-33. PubMed ID: 17885021
    [Abstract] [Full Text] [Related]

  • 20. Fibronectin stimulates non-small cell lung carcinoma cell growth through activation of Akt/mammalian target of rapamycin/S6 kinase and inactivation of LKB1/AMP-activated protein kinase signal pathways.
    Han S, Khuri FR, Roman J.
    Cancer Res; 2006 Jan 01; 66(1):315-23. PubMed ID: 16397245
    [Abstract] [Full Text] [Related]

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