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236 related items for PubMed ID: 15292249

  • 21. cAMP-dependent activation of mammalian target of rapamycin (mTOR) in thyroid cells. Implication in mitogenesis and activation of CDK4.
    Blancquaert S, Wang L, Paternot S, Coulonval K, Dumont JE, Harris TE, Roger PP.
    Mol Endocrinol; 2010 Jul; 24(7):1453-68. PubMed ID: 20484410
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  • 22. Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. A negative feedback mechanism leading to insulin resistance in skeletal muscle cells.
    Tremblay F, Marette A.
    J Biol Chem; 2001 Oct 12; 276(41):38052-60. PubMed ID: 11498541
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  • 23. Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance.
    Khamzina L, Veilleux A, Bergeron S, Marette A.
    Endocrinology; 2005 Mar 12; 146(3):1473-81. PubMed ID: 15604215
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  • 24. L-leucine availability regulates phosphatidylinositol 3-kinase, p70 S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammalian target of rapamycin (mTOR) pathway in the L-leucine-induced up-regulation of system A amino acid transport.
    Peyrollier K, Hajduch E, Blair AS, Hyde R, Hundal HS.
    Biochem J; 2000 Sep 01; 350 Pt 2(Pt 2):361-8. PubMed ID: 10947949
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  • 27. Determinants of rapamycin sensitivity in breast cancer cells.
    Noh WC, Mondesire WH, Peng J, Jian W, Zhang H, Dong J, Mills GB, Hung MC, Meric-Bernstam F.
    Clin Cancer Res; 2004 Feb 01; 10(3):1013-23. PubMed ID: 14871980
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  • 28. Control of Ser2448 phosphorylation in the mammalian target of rapamycin by insulin and skeletal muscle load.
    Reynolds TH, Bodine SC, Lawrence JC.
    J Biol Chem; 2002 May 17; 277(20):17657-62. PubMed ID: 11884412
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  • 29. Endotoxin disrupts the leucine-signaling pathway involving phosphorylation of mTOR, 4E-BP1, and S6K1 in skeletal muscle.
    Lang CH, Frost RA.
    J Cell Physiol; 2005 Apr 17; 203(1):144-55. PubMed ID: 15389631
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  • 30. Role of mTOR in the degradation of IRS-1: regulation of PP2A activity.
    Hartley D, Cooper GM.
    J Cell Biochem; 2002 Apr 17; 85(2):304-14. PubMed ID: 11948686
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  • 31. Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells.
    Jiang ZY, Zhou QL, Holik J, Patel S, Leszyk J, Coleman K, Chouinard M, Czech MP.
    J Biol Chem; 2005 Jun 03; 280(22):21622-8. PubMed ID: 15799971
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  • 32. Protein kinase B localization and activation differentially affect S6 kinase 1 activity and eukaryotic translation initiation factor 4E-binding protein 1 phosphorylation.
    Dufner A, Andjelkovic M, Burgering BM, Hemmings BA, Thomas G.
    Mol Cell Biol; 1999 Jun 03; 19(6):4525-34. PubMed ID: 10330191
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  • 36. Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.
    Navé BT, Ouwens M, Withers DJ, Alessi DR, Shepherd PR.
    Biochem J; 1999 Dec 01; 344 Pt 2(Pt 2):427-31. PubMed ID: 10567225
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  • 37. Activation by insulin and amino acids of signaling components leading to translation initiation in skeletal muscle of neonatal pigs is developmentally regulated.
    Suryawan A, Orellana RA, Nguyen HV, Jeyapalan AS, Fleming JR, Davis TA.
    Am J Physiol Endocrinol Metab; 2007 Dec 01; 293(6):E1597-605. PubMed ID: 17878222
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  • 38. Effects of rapamycin on cell proliferation and phosphorylation of mTOR and p70(S6K) in HepG2 and HepG2 cells overexpressing constitutively active Akt/PKB.
    Varma S, Khandelwal RL.
    Biochim Biophys Acta; 2007 Jan 01; 1770(1):71-8. PubMed ID: 16952420
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  • 39. Inhibition of the mTOR/p70S6K pathway is not involved in the insulin-sensitizing effect of AMPK on cardiac glucose uptake.
    Ginion A, Auquier J, Benton CR, Mouton C, Vanoverschelde JL, Hue L, Horman S, Beauloye C, Bertrand L.
    Am J Physiol Heart Circ Physiol; 2011 Aug 01; 301(2):H469-77. PubMed ID: 21602475
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  • 40. Inhibition of insulin signaling and adipogenesis by rapamycin: effect on phosphorylation of p70 S6 kinase vs eIF4E-BP1.
    El-Chaâr D, Gagnon A, Sorisky A.
    Int J Obes Relat Metab Disord; 2004 Feb 01; 28(2):191-8. PubMed ID: 14970836
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