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594 related items for PubMed ID: 15292252

  • 1. p38 MAPK mediates gamma-irradiation-induced endothelial cell apoptosis, and vascular endothelial growth factor protects endothelial cells through the phosphoinositide 3-kinase-Akt-Bcl-2 pathway.
    Kumar P, Miller AI, Polverini PJ.
    J Biol Chem; 2004 Oct 08; 279(41):43352-60. PubMed ID: 15292252
    [Abstract] [Full Text] [Related]

  • 2. Opposite effects of Ha-Ras and Ki-Ras on radiation-induced apoptosis via differential activation of PI3K/Akt and Rac/p38 mitogen-activated protein kinase signaling pathways.
    Choi JA, Park MT, Kang CM, Um HD, Bae S, Lee KH, Kim TH, Kim JH, Cho CK, Lee YS, Chung HY, Lee SJ.
    Oncogene; 2004 Jan 08; 23(1):9-20. PubMed ID: 14712206
    [Abstract] [Full Text] [Related]

  • 3. Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells.
    Gratton JP, Morales-Ruiz M, Kureishi Y, Fulton D, Walsh K, Sessa WC.
    J Biol Chem; 2001 Aug 10; 276(32):30359-65. PubMed ID: 11387313
    [Abstract] [Full Text] [Related]

  • 4. Bcl-xL mediates a survival mechanism independent of the phosphoinositide 3-kinase/Akt pathway in prostate cancer cells.
    Yang CC, Lin HP, Chen CS, Yang YT, Tseng PH, Rangnekar VM, Chen CS.
    J Biol Chem; 2003 Jul 11; 278(28):25872-8. PubMed ID: 12738789
    [Abstract] [Full Text] [Related]

  • 5. Bcl-2 protects endothelial cells against gamma-radiation via a Raf-MEK-ERK-survivin signaling pathway that is independent of cytochrome c release.
    Kumar P, Coltas IK, Kumar B, Chepeha DB, Bradford CR, Polverini PJ.
    Cancer Res; 2007 Feb 01; 67(3):1193-202. PubMed ID: 17283155
    [Abstract] [Full Text] [Related]

  • 6. Differential activation of the phosphatidylinositol 3'-kinase/Akt survival pathway by ionizing radiation in tumor and primary endothelial cells.
    Zingg D, Riesterer O, Fabbro D, Glanzmann C, Bodis S, Pruschy M.
    Cancer Res; 2004 Aug 01; 64(15):5398-406. PubMed ID: 15289348
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of phosphatidylinositol 3-kinase-Akt signaling blocks growth, promotes apoptosis, and enhances sensitivity of small cell lung cancer cells to chemotherapy.
    Krystal GW, Sulanke G, Litz J.
    Mol Cancer Ther; 2002 Sep 01; 1(11):913-22. PubMed ID: 12481412
    [Abstract] [Full Text] [Related]

  • 8. VEGF induces Tie2 shedding via a phosphoinositide 3-kinase/Akt dependent pathway to modulate Tie2 signaling.
    Findley CM, Cudmore MJ, Ahmed A, Kontos CD.
    Arterioscler Thromb Vasc Biol; 2007 Dec 01; 27(12):2619-26. PubMed ID: 17901375
    [Abstract] [Full Text] [Related]

  • 9. The lethal effects of pharmacological cyclin-dependent kinase inhibitors in human leukemia cells proceed through a phosphatidylinositol 3-kinase/Akt-dependent process.
    Yu C, Rahmani M, Dai Y, Conrad D, Krystal G, Dent P, Grant S.
    Cancer Res; 2003 Apr 15; 63(8):1822-33. PubMed ID: 12702569
    [Abstract] [Full Text] [Related]

  • 10. L6 myoblast differentiation is modulated by Cdk5 via the PI3K-AKT-p70S6K signaling pathway.
    Sarker KP, Lee KY.
    Oncogene; 2004 Aug 12; 23(36):6064-70. PubMed ID: 15208659
    [Abstract] [Full Text] [Related]

  • 11. In vitro study of HIF-1 activation and VEGF release by bFGF in the T47D breast cancer cell line under normoxic conditions: involvement of PI-3K/Akt and MEK1/ERK pathways.
    Shi YH, Wang YX, Bingle L, Gong LH, Heng WJ, Li Y, Fang WG.
    J Pathol; 2005 Mar 12; 205(4):530-6. PubMed ID: 15714461
    [Abstract] [Full Text] [Related]

  • 12. Visfatin induces human endothelial VEGF and MMP-2/9 production via MAPK and PI3K/Akt signalling pathways: novel insights into visfatin-induced angiogenesis.
    Adya R, Tan BK, Punn A, Chen J, Randeva HS.
    Cardiovasc Res; 2008 May 01; 78(2):356-65. PubMed ID: 18093986
    [Abstract] [Full Text] [Related]

  • 13. Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance.
    Campbell RA, Bhat-Nakshatri P, Patel NM, Constantinidou D, Ali S, Nakshatri H.
    J Biol Chem; 2001 Mar 30; 276(13):9817-24. PubMed ID: 11139588
    [Abstract] [Full Text] [Related]

  • 14. Insulin-like growth factor-1 regulates endogenous RUNX2 activity in endothelial cells through a phosphatidylinositol 3-kinase/ERK-dependent and Akt-independent signaling pathway.
    Qiao M, Shapiro P, Kumar R, Passaniti A.
    J Biol Chem; 2004 Oct 08; 279(41):42709-18. PubMed ID: 15304489
    [Abstract] [Full Text] [Related]

  • 15. Cardiotrophin-1 phosphorylates akt and BAD, and prolongs cell survival via a PI3K-dependent pathway in cardiac myocytes.
    Kuwahara K, Saito Y, Kishimoto I, Miyamoto Y, Harada M, Ogawa E, Hamanaka I, Kajiyama N, Takahashi N, Izumi T, Kawakami R, Nakao K.
    J Mol Cell Cardiol; 2000 Aug 08; 32(8):1385-94. PubMed ID: 10900165
    [Abstract] [Full Text] [Related]

  • 16. Tumor necrosis factor-alpha induces insulin resistance in endothelial cells via a p38 mitogen-activated protein kinase-dependent pathway.
    Li G, Barrett EJ, Barrett MO, Cao W, Liu Z.
    Endocrinology; 2007 Jul 08; 148(7):3356-63. PubMed ID: 17446186
    [Abstract] [Full Text] [Related]

  • 17. Migration inhibitory factor mediates angiogenesis via mitogen-activated protein kinase and phosphatidylinositol kinase.
    Amin MA, Volpert OV, Woods JM, Kumar P, Harlow LA, Koch AE.
    Circ Res; 2003 Aug 22; 93(4):321-9. PubMed ID: 12881477
    [Abstract] [Full Text] [Related]

  • 18. Vascular endothelial growth factor induces protein kinase C (PKC)-dependent Akt/PKB activation and phosphatidylinositol 3'-kinase-mediates PKC delta phosphorylation: role of PKC in angiogenesis.
    Gliki G, Wheeler-Jones C, Zachary I.
    Cell Biol Int; 2002 Aug 22; 26(9):751-9. PubMed ID: 12377207
    [Abstract] [Full Text] [Related]

  • 19. Basic fibroblast growth factor inhibits radiation-induced apoptosis of HUVECs. I. The PI3K/AKT pathway and induction of phosphorylation of BAD.
    Gu Q, Wang D, Wang X, Peng R, Liu J, Jiang T, Wang Z, Wang S, Deng H.
    Radiat Res; 2004 Jun 22; 161(6):692-702. PubMed ID: 15161350
    [Abstract] [Full Text] [Related]

  • 20. Relevance of mitogen activated protein kinase (MAPK) and phosphotidylinositol-3-kinase/protein kinase B (PI3K/PKB) pathways to induction of apoptosis by curcumin in breast cells.
    Squires MS, Hudson EA, Howells L, Sale S, Houghton CE, Jones JL, Fox LH, Dickens M, Prigent SA, Manson MM.
    Biochem Pharmacol; 2003 Feb 01; 65(3):361-76. PubMed ID: 12527329
    [Abstract] [Full Text] [Related]

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