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Journal Abstract Search

445 related items for PubMed ID: 15294873

  • 1.
    ; . PubMed ID:
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  • 2. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
    Jaarsma D, Haasdijk ED, Grashorn JA, Hawkins R, van Duijn W, Verspaget HW, London J, Holstege JC.
    Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261
    [Abstract] [Full Text] [Related]

  • 3. Overexpression of Abeta is associated with acceleration of onset of motor impairment and superoxide dismutase 1 aggregation in an amyotrophic lateral sclerosis mouse model.
    Li QX, Mok SS, Laughton KM, McLean CA, Volitakis I, Cherny RA, Cheung NS, White AR, Masters CL.
    Aging Cell; 2006 Apr; 5(2):153-65. PubMed ID: 16626394
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  • 4. Glutamate AMPA receptors change in motor neurons of SOD1G93A transgenic mice and their inhibition by a noncompetitive antagonist ameliorates the progression of amytrophic lateral sclerosis-like disease.
    Tortarolo M, Grignaschi G, Calvaresi N, Zennaro E, Spaltro G, Colovic M, Fracasso C, Guiso G, Elger B, Schneider H, Seilheimer B, Caccia S, Bendotti C.
    J Neurosci Res; 2006 Jan; 83(1):134-46. PubMed ID: 16323214
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  • 5. Trehalose decreases mutant SOD1 expression and alleviates motor deficiency in early but not end-stage amyotrophic lateral sclerosis in a SOD1-G93A mouse model.
    Li Y, Guo Y, Wang X, Yu X, Duan W, Hong K, Wang J, Han H, Li C.
    Neuroscience; 2015 Jul 09; 298():12-25. PubMed ID: 25841320
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  • 6. Enhancing mitochondrial calcium buffering capacity reduces aggregation of misfolded SOD1 and motor neuron cell death without extending survival in mouse models of inherited amyotrophic lateral sclerosis.
    Parone PA, Da Cruz S, Han JS, McAlonis-Downes M, Vetto AP, Lee SK, Tseng E, Cleveland DW.
    J Neurosci; 2013 Mar 13; 33(11):4657-71. PubMed ID: 23486940
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  • 7. GluR2 deficiency accelerates motor neuron degeneration in a mouse model of amyotrophic lateral sclerosis.
    Van Damme P, Braeken D, Callewaert G, Robberecht W, Van Den Bosch L.
    J Neuropathol Exp Neurol; 2005 Jul 13; 64(7):605-12. PubMed ID: 16042312
    [Abstract] [Full Text] [Related]

  • 8. A copper-deficient form of mutant Cu/Zn-superoxide dismutase as an early pathological species in amyotrophic lateral sclerosis.
    Tokuda E, Nomura T, Ohara S, Watanabe S, Yamanaka K, Morisaki Y, Misawa H, Furukawa Y.
    Biochim Biophys Acta Mol Basis Dis; 2018 Jun 13; 1864(6 Pt A):2119-2130. PubMed ID: 29551730
    [Abstract] [Full Text] [Related]

  • 9. Late-onset motoneuron disease caused by a functionally modified AMPA receptor subunit.
    Kuner R, Groom AJ, Bresink I, Kornau HC, Stefovska V, Müller G, Hartmann B, Tschauner K, Waibel S, Ludolph AC, Ikonomidou C, Seeburg PH, Turski L.
    Proc Natl Acad Sci U S A; 2005 Apr 19; 102(16):5826-31. PubMed ID: 15827116
    [Abstract] [Full Text] [Related]

  • 10. Antisense peptide nucleic acid targeting GluR3 delays disease onset and progression in the SOD1 G93A mouse model of familial ALS.
    Rembach A, Turner BJ, Bruce S, Cheah IK, Scott RL, Lopes EC, Zagami CJ, Beart PM, Cheung NS, Langford SJ, Cheema SS.
    J Neurosci Res; 2004 Aug 15; 77(4):573-82. PubMed ID: 15264227
    [Abstract] [Full Text] [Related]

  • 11. Genetic ablation of phospholipase C delta 1 increases survival in SOD1(G93A) mice.
    Staats KA, Van Helleputte L, Jones AR, Bento-Abreu A, Van Hoecke A, Shatunov A, Simpson CL, Lemmens R, Jaspers T, Fukami K, Nakamura Y, Brown RH, Van Damme P, Liston A, Robberecht W, Al-Chalabi A, Van Den Bosch L.
    Neurobiol Dis; 2013 Dec 15; 60():11-7. PubMed ID: 23969236
    [Abstract] [Full Text] [Related]

  • 12. Early vacuolization and mitochondrial damage in motor neurons of FALS mice are not associated with apoptosis or with changes in cytochrome oxidase histochemical reactivity.
    Bendotti C, Calvaresi N, Chiveri L, Prelle A, Moggio M, Braga M, Silani V, De Biasi S.
    J Neurol Sci; 2001 Oct 15; 191(1-2):25-33. PubMed ID: 11676989
    [Abstract] [Full Text] [Related]

  • 13. Neuregulin 1 confers neuroprotection in SOD1-linked amyotrophic lateral sclerosis mice via restoration of C-boutons of spinal motor neurons.
    Lasiene J, Komine O, Fujimori-Tonou N, Powers B, Endo F, Watanabe S, Shijie J, Ravits J, Horner P, Misawa H, Yamanaka K.
    Acta Neuropathol Commun; 2016 Feb 18; 4():15. PubMed ID: 26891847
    [Abstract] [Full Text] [Related]

  • 14. Somatodendritic accumulation of misfolded SOD1-L126Z in motor neurons mediates degeneration: alphaB-crystallin modulates aggregation.
    Wang J, Xu G, Li H, Gonzales V, Fromholt D, Karch C, Copeland NG, Jenkins NA, Borchelt DR.
    Hum Mol Genet; 2005 Aug 15; 14(16):2335-47. PubMed ID: 16000321
    [Abstract] [Full Text] [Related]

  • 15. Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues.
    Watanabe M, Dykes-Hoberg M, Culotta VC, Price DL, Wong PC, Rothstein JD.
    Neurobiol Dis; 2001 Dec 15; 8(6):933-41. PubMed ID: 11741389
    [Abstract] [Full Text] [Related]

  • 16. Underediting of GluR2 mRNA, a neuronal death inducing molecular change in sporadic ALS, does not occur in motor neurons in ALS1 or SBMA.
    Kawahara Y, Sun H, Ito K, Hideyama T, Aoki M, Sobue G, Tsuji S, Kwak S.
    Neurosci Res; 2006 Jan 15; 54(1):11-4. PubMed ID: 16225946
    [Abstract] [Full Text] [Related]

  • 17. Amyotrophic lateral sclerosis-related mutant superoxide dismutase 1 aggregates inhibit 14-3-3-mediated cell survival by sequestration into the JUNQ compartment.
    Park JH, Jang HR, Lee IY, Oh HK, Choi EJ, Rhim H, Kang S.
    Hum Mol Genet; 2017 Sep 15; 26(18):3615-3629. PubMed ID: 28666328
    [Abstract] [Full Text] [Related]

  • 18. Prion-like propagation of mutant SOD1 misfolding and motor neuron disease spread along neuroanatomical pathways.
    Ayers JI, Fromholt SE, O'Neal VM, Diamond JH, Borchelt DR.
    Acta Neuropathol; 2016 Jan 15; 131(1):103-14. PubMed ID: 26650262
    [Abstract] [Full Text] [Related]

  • 19. Increased expression of the glial glutamate transporter EAAT2 modulates excitotoxicity and delays the onset but not the outcome of ALS in mice.
    Guo H, Lai L, Butchbach ME, Stockinger MP, Shan X, Bishop GA, Lin CL.
    Hum Mol Genet; 2003 Oct 01; 12(19):2519-32. PubMed ID: 12915461
    [Abstract] [Full Text] [Related]

  • 20. Light and electron microscopic distribution of the AMPA receptor subunit, GluR2, in the spinal cord of control and G86R mutant superoxide dismutase transgenic mice.
    Morrison BM, Janssen WG, Gordon JW, Morrison JH.
    J Comp Neurol; 1998 Jun 15; 395(4):523-34. PubMed ID: 9619504
    [Abstract] [Full Text] [Related]

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