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Journal Abstract Search

126 related items for PubMed ID: 15299851

  • 1. Comparison of ternary complexes of Pneumocystis carinii and wild-type human dihydrofolate reductase with coenzyme NADPH and a novel classical antitumor furo[2,3-d]pyrimidine antifolate.
    Cody V, Galitsky N, Luft JR, Pangborn W, Gangjee A, Devraj R, Queener SF, Blakley RL.
    Acta Crystallogr D Biol Crystallogr; 1997 Nov 01; 53(Pt 6):638-49. PubMed ID: 15299851
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  • 2. Comparison of ternary crystal complexes of F31 variants of human dihydrofolate reductase with NADPH and a classical antitumor furopyrimidine.
    Cody V, Galitsky N, Luft JR, Pangborn W, Blakley RL, Gangjee A.
    Anticancer Drug Des; 1998 Jun 01; 13(4):307-15. PubMed ID: 9627670
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  • 8. New insights into DHFR interactions: analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions.
    Cody V, Pace J, Chisum K, Rosowsky A.
    Proteins; 2006 Dec 01; 65(4):959-69. PubMed ID: 17019704
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  • 10. Structure-activity correlations for three pyrido[2,3-d]pyrimidine antifolates binding to human and Pneumocystis carinii dihydrofolate reductase.
    Cody V, Pace J, Namjoshi OA, Gangjee A.
    Acta Crystallogr F Struct Biol Commun; 2015 Jun 01; 71(Pt 6):799-803. PubMed ID: 26057816
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  • 12. Detection of long-lived bound water molecules in complexes of human dihydrofolate reductase with methotrexate and NADPH.
    Meiering EM, Wagner G.
    J Mol Biol; 1995 Mar 24; 247(2):294-308. PubMed ID: 7707376
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  • 13. Structure-based enzyme inhibitor design: modeling studies and crystal structure analysis of Pneumocystis carinii dihydrofolate reductase ternary complex with PT653 and NADPH.
    Cody V, Galitsky N, Luft JR, Pangborn W, Rosowsky A, Queener SF.
    Acta Crystallogr D Biol Crystallogr; 2002 Jun 24; 58(Pt 6 Pt 2):946-54. PubMed ID: 12037296
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  • 14. Crystal structures of Escherichia coli dihydrofolate reductase complexed with 5-formyltetrahydrofolate (folinic acid) in two space groups: evidence for enolization of pteridine O4.
    Lee H, Reyes VM, Kraut J.
    Biochemistry; 1996 Jun 04; 35(22):7012-20. PubMed ID: 8679526
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  • 15. Correlations of inhibitor kinetics for Pneumocystis jirovecii and human dihydrofolate reductase with structural data for human active site mutant enzyme complexes.
    Cody V, Pace J, Makin J, Piraino J, Queener SF, Rosowsky A.
    Biochemistry; 2009 Mar 03; 48(8):1702-11. PubMed ID: 19196009
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  • 17. Selective Pneumocystis carinii dihydrofolate reductase inhibitors: design, synthesis, and biological evaluation of new 2,4-diamino-5-substituted-furo[2,3-d]pyrimidines.
    Gangjee A, Guo X, Queener SF, Cody V, Galitsky N, Luft JR, Pangborn W.
    J Med Chem; 1998 Apr 09; 41(8):1263-71. PubMed ID: 9548816
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