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Journal Abstract Search


160 related items for PubMed ID: 15301157

  • 1. Cryopreserved rat, dog and monkey hepatocytes: measurement of drug metabolizing enzymes in suspensions and cultures.
    Hewitt NJ, Utesch D.
    Hum Exp Toxicol; 2004 Jun; 23(6):307-16. PubMed ID: 15301157
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  • 2. Metabolic activity of fresh and cryopreserved cynomolgus monkey (Macaca fascicularis) hepatocytes.
    Hewitt NJ, Fischer T, Zuehlke U, Oesch F, Utesch D.
    Xenobiotica; 2000 Jul; 30(7):665-81. PubMed ID: 10963058
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  • 4. Use of a cocktail of probe substrates for drug-metabolizing enzymes for the assessment of the metabolic capacity of hepatocyte preparations.
    Floby E, Briem S, Terelius Y, Sohlenius-Sternbeck AK.
    Xenobiotica; 2004 Jul; 34(11-12):949-59. PubMed ID: 15801540
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  • 5. A comprehensive evaluation of metabolic activity and intrinsic clearance in suspensions and monolayer cultures of cryopreserved primary human hepatocytes.
    Smith CM, Nolan CK, Edwards MA, Hatfield JB, Stewart TW, Ferguson SS, Lecluyse EL, Sahi J.
    J Pharm Sci; 2012 Oct; 101(10):3989-4002. PubMed ID: 22806329
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  • 7. Metabolic activity of fresh and cryopreserved dog hepatocyte suspensions.
    Swales NJ, Utesch D.
    Xenobiotica; 1998 Oct; 28(10):937-48. PubMed ID: 9849641
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  • 8. Effect of honokiol on the induction of drug-metabolizing enzymes in human hepatocytes.
    Cho YY, Jeong HU, Kim JH, Lee HS.
    Drug Des Devel Ther; 2014 Oct; 8():2137-45. PubMed ID: 25395831
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  • 10. Cryopreservation of rat and mouse hepatocytes. I. Comparative viability studies.
    Swales NJ, Luong C, Caldwell J.
    Drug Metab Dispos; 1996 Nov; 24(11):1218-23. PubMed ID: 8937856
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  • 11. Cryopreserved human hepatocytes: characterization of drug-metabolizing enzyme activities and applications in higher throughput screening assays for hepatotoxicity, metabolic stability, and drug-drug interaction potential.
    Li AP, Lu C, Brent JA, Pham C, Fackett A, Ruegg CE, Silber PM.
    Chem Biol Interact; 1999 Jun 01; 121(1):17-35. PubMed ID: 10418968
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  • 12. Studies comparing in vivo:in vitro metabolism of three pharmaceutical compounds in rat, dog, monkey, and human using cryopreserved hepatocytes, microsomes, and collagen gel immobilized hepatocyte cultures.
    Hewitt NJ, Bühring KU, Dasenbrock J, Haunschild J, Ladstetter B, Utesch D.
    Drug Metab Dispos; 2001 Jul 01; 29(7):1042-50. PubMed ID: 11408372
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  • 13. Cryopreserved primary hepatocytes as a constantly available in vitro model for the evaluation of human and animal drug metabolism and enzyme induction.
    Hengstler JG, Utesch D, Steinberg P, Platt KL, Diener B, Ringel M, Swales N, Fischer T, Biefang K, Gerl M, Böttger T, Oesch F.
    Drug Metab Rev; 2000 Feb 01; 32(1):81-118. PubMed ID: 10711408
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  • 14. Phase I and II metabolism and carbohydrate metabolism in cultured cryopreserved porcine hepatocytes.
    Loven AD, Olsen AK, Friis C, Andersen B.
    Chem Biol Interact; 2005 Jun 30; 155(1-2):21-30. PubMed ID: 15950209
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  • 15. Use of isolated hepatocyte preparations for cytochrome P450 inhibition studies: comparison with microsomes for Ki determination.
    Brown HS, Chadwick A, Houston JB.
    Drug Metab Dispos; 2007 Nov 30; 35(11):2119-26. PubMed ID: 17724064
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  • 16. Development of a novel in vitro model to predict hepatic clearance using fresh, cryopreserved, and sandwich-cultured hepatocytes.
    Lau YY, Sapidou E, Cui X, White RE, Cheng KC.
    Drug Metab Dispos; 2002 Dec 30; 30(12):1446-54. PubMed ID: 12433818
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  • 17. Cryopreservation of rat and dog hepatocytes for studies of xenobiotic metabolism and activation.
    Powis G, Santone KS, Melder DC, Thomas L, Moore DJ, Wilke TJ.
    Drug Metab Dispos; 1987 Dec 30; 15(6):826-32. PubMed ID: 2893709
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  • 19. Comparison of Drug Metabolism and Its Related Hepatotoxic Effects in HepaRG, Cryopreserved Human Hepatocytes, and HepG2 Cell Cultures.
    Yokoyama Y, Sasaki Y, Terasaki N, Kawataki T, Takekawa K, Iwase Y, Shimizu T, Sanoh S, Ohta S.
    Biol Pharm Bull; 2018 May 01; 41(5):722-732. PubMed ID: 29445054
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  • 20. A Novel In vitro Experimental System for the Evaluation of Enteric Drug Metabolism: Cofactor-Supplemented Permeabilized Cryopreserved Human Enterocytes (MetMax™ Cryopreserved Human Enterocytes).
    Li AP, Amaral K, Ho MD.
    Drug Metab Lett; 2018 May 01; 12(2):132-137. PubMed ID: 30124163
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