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598 related items for PubMed ID: 15306590

  • 1. T-bet upregulation and subsequent interleukin 12 stimulation are essential for induction of Th1 mediated immunopathology in Crohn's disease.
    Matsuoka K, Inoue N, Sato T, Okamoto S, Hisamatsu T, Kishi Y, Sakuraba A, Hitotsumatsu O, Ogata H, Koganei K, Fukushima T, Kanai T, Watanabe M, Ishii H, Hibi T.
    Gut; 2004 Sep; 53(9):1303-8. PubMed ID: 15306590
    [Abstract] [Full Text] [Related]

  • 2. Th1-mediated intestinal inflammation in Crohn's disease may be induced by activation of lamina propria lymphocytes through synergistic stimulation of interleukin-12 and interleukin-18 without T cell receptor engagement.
    Okazawa A, Kanai T, Watanabe M, Yamazaki M, Inoue N, Ikeda M, Kurimoto M, Ishii H, Hibi T.
    Am J Gastroenterol; 2002 Dec; 97(12):3108-17. PubMed ID: 12492197
    [Abstract] [Full Text] [Related]

  • 3. Instruction of naive CD4+ T-cell fate to T-bet expression and T helper 1 development: roles of T-cell receptor-mediated signals.
    Ariga H, Shimohakamada Y, Nakada M, Tokunaga T, Kikuchi T, Kariyone A, Tamura T, Takatsu K.
    Immunology; 2007 Oct; 122(2):210-21. PubMed ID: 17490433
    [Abstract] [Full Text] [Related]

  • 4. IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease.
    Kobayashi T, Okamoto S, Hisamatsu T, Kamada N, Chinen H, Saito R, Kitazume MT, Nakazawa A, Sugita A, Koganei K, Isobe K, Hibi T.
    Gut; 2008 Dec; 57(12):1682-9. PubMed ID: 18653729
    [Abstract] [Full Text] [Related]

  • 5. IL-12 up-regulates T-bet independently of IFN-gamma in human CD4+ T cells.
    Ylikoski E, Lund R, Kyläniemi M, Filén S, Kilpeläinen M, Savolainen J, Lahesmaa R.
    Eur J Immunol; 2005 Nov; 35(11):3297-306. PubMed ID: 16220539
    [Abstract] [Full Text] [Related]

  • 6. Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5.
    Fuss IJ, Neurath M, Boirivant M, Klein JS, de la Motte C, Strong SA, Fiocchi C, Strober W.
    J Immunol; 1996 Aug 01; 157(3):1261-70. PubMed ID: 8757634
    [Abstract] [Full Text] [Related]

  • 7. Elevated gene expression of Th1/Th2 associated transcription factors is correlated with disease activity in patients with systemic lupus erythematosus.
    Lit LC, Wong CK, Li EK, Tam LS, Lam CW, Lo YM.
    J Rheumatol; 2007 Jan 01; 34(1):89-96. PubMed ID: 17117487
    [Abstract] [Full Text] [Related]

  • 8. Blockade of transforming growth factor beta upregulates T-box transcription factor T-bet, and increases T helper cell type 1 cytokine and matrix metalloproteinase-3 production in the human gut mucosa.
    Di Sabatino A, Pickard KM, Rampton D, Kruidenier L, Rovedatti L, Leakey NA, Corazza GR, Monteleone G, MacDonald TT.
    Gut; 2008 May 01; 57(5):605-12. PubMed ID: 18178611
    [Abstract] [Full Text] [Related]

  • 9. Effect of treatment of rheumatoid arthritis with infliximab on IFN gamma, IL4, T-bet, and GATA-3 expression: link with improvement of systemic inflammation and disease activity.
    Kawashima M, Miossec P.
    Ann Rheum Dis; 2005 Mar 01; 64(3):415-8. PubMed ID: 15286007
    [Abstract] [Full Text] [Related]

  • 10. T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells.
    Afkarian M, Sedy JR, Yang J, Jacobson NG, Cereb N, Yang SY, Murphy TL, Murphy KM.
    Nat Immunol; 2002 Jun 01; 3(6):549-57. PubMed ID: 12006974
    [Abstract] [Full Text] [Related]

  • 11. Upregulation of interferon-gamma and interleukin-4, Th cell-derived cytokines by So-Shi-Ho-Tang (Sho-Saiko-To) occurs at the level of antigen presenting cells, but not CD4 T cells.
    Kang H, Choi TW, Ahn KS, Lee JY, Ham IH, Choi HY, Shim ES, Sohn NW.
    J Ethnopharmacol; 2009 May 04; 123(1):6-14. PubMed ID: 19429332
    [Abstract] [Full Text] [Related]

  • 12. Interleukin-25 inhibits interleukin-12 production and Th1 cell-driven inflammation in the gut.
    Caruso R, Sarra M, Stolfi C, Rizzo A, Fina D, Fantini MC, Pallone F, MacDonald TT, Monteleone G.
    Gastroenterology; 2009 Jun 04; 136(7):2270-9. PubMed ID: 19505427
    [Abstract] [Full Text] [Related]

  • 13. Interleukin-12 and -18 levels in peritoneal dialysate effluent correlate with the outcome of peritonitis in patients undergoing peritoneal dialysis: implications for the Type I/Type II T-cell immune response.
    Wang HH, Lin CY.
    Am J Kidney Dis; 2005 Aug 04; 46(2):328-38. PubMed ID: 16112053
    [Abstract] [Full Text] [Related]

  • 14. Differential effects of IFN-alpha on the expression of various TH2 cytokines in human CD4+ T cells.
    Shibuya H, Hirohata S.
    J Allergy Clin Immunol; 2005 Jul 04; 116(1):205-12. PubMed ID: 15990796
    [Abstract] [Full Text] [Related]

  • 15. Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease.
    Parronchi P, Romagnani P, Annunziato F, Sampognaro S, Becchio A, Giannarini L, Maggi E, Pupilli C, Tonelli F, Romagnani S.
    Am J Pathol; 1997 Mar 04; 150(3):823-32. PubMed ID: 9060820
    [Abstract] [Full Text] [Related]

  • 16. Cholera toxin subunit B inhibits IL-12 and IFN-{gamma} production and signaling in experimental colitis and Crohn's disease.
    Coccia EM, Remoli ME, Di Giacinto C, Del Zotto B, Giacomini E, Monteleone G, Boirivant M.
    Gut; 2005 Nov 04; 54(11):1558-64. PubMed ID: 16105891
    [Abstract] [Full Text] [Related]

  • 17. Osteopontin/Eta-1 upregulated in Crohn's disease regulates the Th1 immune response.
    Sato T, Nakai T, Tamura N, Okamoto S, Matsuoka K, Sakuraba A, Fukushima T, Uede T, Hibi T.
    Gut; 2005 Sep 04; 54(9):1254-62. PubMed ID: 16099792
    [Abstract] [Full Text] [Related]

  • 18. pSTAT1, pSTAT3, and T-bet expression in peripheral blood mononuclear cells from relapsing-remitting multiple sclerosis patients correlates with disease activity.
    Frisullo G, Angelucci F, Caggiula M, Nociti V, Iorio R, Patanella AK, Sancricca C, Mirabella M, Tonali PA, Batocchi AP.
    J Neurosci Res; 2006 Oct 04; 84(5):1027-36. PubMed ID: 16865709
    [Abstract] [Full Text] [Related]

  • 19. In vitro analysis of interferon gamma (IFN-gamma) and interleukin-12 (IL-12) production and their effects in ileal Crohn's disease.
    Colpaert S, Vastraelen K, Liu Z, Maerten P, Shen C, Penninckx F, Geboes K, Rutgeerts P, Ceuppens JL.
    Eur Cytokine Netw; 2002 Oct 04; 13(4):431-7. PubMed ID: 12517728
    [Abstract] [Full Text] [Related]

  • 20. [Profiles of type 1 and type 2 T cells in chronic idiopathic thrombocytopenic purpura].
    Wang TT, Zhao H, Ren H, Guo JH, Xu MQ, Yang RC, Han ZC.
    Zhonghua Yi Xue Za Zhi; 2006 Mar 14; 86(10):669-73. PubMed ID: 16681922
    [Abstract] [Full Text] [Related]

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