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Journal Abstract Search

556 related items for PubMed ID: 15314154

  • 1. Disruption of the SH2-B gene causes age-dependent insulin resistance and glucose intolerance.
    Duan C, Yang H, White MF, Rui L.
    Mol Cell Biol; 2004 Sep; 24(17):7435-43. PubMed ID: 15314154
    [Abstract] [Full Text] [Related]

  • 2. Adapter protein with a pleckstrin homology (PH) and an Src homology 2 (SH2) domain (APS) and SH2-B enhance insulin-receptor autophosphorylation, extracellular-signal-regulated kinase and phosphoinositide 3-kinase-dependent signalling.
    Ahmed Z, Pillay TS.
    Biochem J; 2003 Apr 15; 371(Pt 2):405-12. PubMed ID: 12521378
    [Abstract] [Full Text] [Related]

  • 3. SH2-B promotes insulin receptor substrate 1 (IRS1)- and IRS2-mediated activation of the phosphatidylinositol 3-kinase pathway in response to leptin.
    Duan C, Li M, Rui L.
    J Biol Chem; 2004 Oct 15; 279(42):43684-91. PubMed ID: 15316008
    [Abstract] [Full Text] [Related]

  • 4. GTK tyrosine kinase-induced alteration of IRS-protein signalling in insulin producing cells.
    Annerén C, Welsh M.
    Mol Med; 2002 Nov 15; 8(11):705-13. PubMed ID: 12520087
    [Abstract] [Full Text] [Related]

  • 5. Overexpression of the Shb SH2 domain-protein in insulin-producing cells leads to altered signaling through the IRS-1 and IRS-2 proteins.
    Welsh N, Makeeva N, Welsh M.
    Mol Med; 2002 Nov 15; 8(11):695-704. PubMed ID: 12520086
    [Abstract] [Full Text] [Related]

  • 6. Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice.
    Cooney GJ, Lyons RJ, Crew AJ, Jensen TE, Molero JC, Mitchell CJ, Biden TJ, Ormandy CJ, James DE, Daly RJ.
    EMBO J; 2004 Feb 11; 23(3):582-93. PubMed ID: 14749734
    [Abstract] [Full Text] [Related]

  • 7. Early steps of insulin action in the skin of intact rats.
    Pelegrinelli FF, Thirone AC, Gasparetti AL, Araujo EP, Velloso LA, Saad MJ.
    J Invest Dermatol; 2001 Oct 11; 117(4):971-6. PubMed ID: 11676840
    [Abstract] [Full Text] [Related]

  • 8. Identification of SH2-B as a key regulator of leptin sensitivity, energy balance, and body weight in mice.
    Ren D, Li M, Duan C, Rui L.
    Cell Metab; 2005 Aug 11; 2(2):95-104. PubMed ID: 16098827
    [Abstract] [Full Text] [Related]

  • 9. Distinct Grb10 domain requirements for effects on glucose uptake and insulin signaling.
    Mori K, Giovannone B, Smith RJ.
    Mol Cell Endocrinol; 2005 Jan 31; 230(1-2):39-50. PubMed ID: 15664450
    [Abstract] [Full Text] [Related]

  • 10. Adenovirus-mediated chronic "hyper-resistinemia" leads to in vivo insulin resistance in normal rats.
    Satoh H, Nguyen MT, Miles PD, Imamura T, Usui I, Olefsky JM.
    J Clin Invest; 2004 Jul 31; 114(2):224-31. PubMed ID: 15254589
    [Abstract] [Full Text] [Related]

  • 11. Free fatty acid-induced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic acid synthesis in the pancreatic beta-cell line INS-1.
    Cousin SP, Hügl SR, Wrede CE, Kajio H, Myers MG, Rhodes CJ.
    Endocrinology; 2001 Jan 31; 142(1):229-40. PubMed ID: 11145586
    [Abstract] [Full Text] [Related]

  • 12. Regulation of IRS-2 tyrosine phosphorylation in fasting and diabetes.
    Rojas FA, Hirata AE, Saad MJ.
    Mol Cell Endocrinol; 2001 Oct 25; 183(1-2):63-9. PubMed ID: 11604226
    [Abstract] [Full Text] [Related]

  • 13. Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta).
    Cho H, Mu J, Kim JK, Thorvaldsen JL, Chu Q, Crenshaw EB, Kaestner KH, Bartolomei MS, Shulman GI, Birnbaum MJ.
    Science; 2001 Jun 01; 292(5522):1728-31. PubMed ID: 11387480
    [Abstract] [Full Text] [Related]

  • 14. Evidence against a role for insulin-signaling proteins PI 3-kinase and Akt in insulin resistance in human skeletal muscle induced by short-term GH infusion.
    Jessen N, Djurhuus CB, Jørgensen JO, Jensen LS, Møller N, Lund S, Schmitz O.
    Am J Physiol Endocrinol Metab; 2005 Jan 01; 288(1):E194-9. PubMed ID: 15339744
    [Abstract] [Full Text] [Related]

  • 15. Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3.
    Kawaguchi T, Yoshida T, Harada M, Hisamoto T, Nagao Y, Ide T, Taniguchi E, Kumemura H, Hanada S, Maeyama M, Baba S, Koga H, Kumashiro R, Ueno T, Ogata H, Yoshimura A, Sata M.
    Am J Pathol; 2004 Nov 01; 165(5):1499-508. PubMed ID: 15509521
    [Abstract] [Full Text] [Related]

  • 16. Molecular mechanism(s) of burn-induced insulin resistance in murine skeletal muscle: role of IRS phosphorylation.
    Zhang Q, Carter EA, Ma BY, White M, Fischman AJ, Tompkins RG.
    Life Sci; 2005 Oct 28; 77(24):3068-77. PubMed ID: 15982669
    [Abstract] [Full Text] [Related]

  • 17. Biomedicine. Insulin resistance takes a trip through the ER.
    Muoio DM, Newgard CB.
    Science; 2004 Oct 15; 306(5695):425-6. PubMed ID: 15486283
    [No Abstract] [Full Text] [Related]

  • 18. SH2B1 enhances insulin sensitivity by both stimulating the insulin receptor and inhibiting tyrosine dephosphorylation of insulin receptor substrate proteins.
    Morris DL, Cho KW, Zhou Y, Rui L.
    Diabetes; 2009 Sep 15; 58(9):2039-47. PubMed ID: 19542202
    [Abstract] [Full Text] [Related]

  • 19. Insulin signalling and insulin actions in the muscles and livers of insulin-resistant, insulin receptor substrate 1-deficient mice.
    Yamauchi T, Tobe K, Tamemoto H, Ueki K, Kaburagi Y, Yamamoto-Honda R, Takahashi Y, Yoshizawa F, Aizawa S, Akanuma Y, Sonenberg N, Yazaki Y, Kadowaki T.
    Mol Cell Biol; 1996 Jun 15; 16(6):3074-84. PubMed ID: 8649419
    [Abstract] [Full Text] [Related]

  • 20. Infusion of beta-endorphin improves insulin resistance in fructose-fed rats.
    Su CF, Chang YY, Pai HH, Liu IM, Lo CY, Cheng JT.
    Horm Metab Res; 2004 Aug 15; 36(8):571-7. PubMed ID: 15326568
    [Abstract] [Full Text] [Related]

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