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Journal Abstract Search


160 related items for PubMed ID: 15317450

  • 1. Determinants of retinoid X receptor transcriptional antagonism.
    Cavasotto CN, Liu G, James SY, Hobbs PD, Peterson VJ, Bhattacharya AA, Kolluri SK, Zhang XK, Leid M, Abagyan R, Liddington RC, Dawson MI.
    J Med Chem; 2004 Aug 26; 47(18):4360-72. PubMed ID: 15317450
    [Abstract] [Full Text] [Related]

  • 2. Retinoids increase human apo C-III expression at the transcriptional level via the retinoid X receptor. Contribution to the hypertriglyceridemic action of retinoids.
    Vu-Dac N, Gervois P, Torra IP, Fruchart JC, Kosykh V, Kooistra T, Princen HM, Dallongeville J, Staels B.
    J Clin Invest; 1998 Aug 01; 102(3):625-32. PubMed ID: 9691099
    [Abstract] [Full Text] [Related]

  • 3. Synthesis, structure-activity relationships, and RARgamma-ligand interactions of nitrogen heteroarotinoids.
    Dhar A, Liu S, Klucik J, Berlin KD, Madler MM, Lu S, Ivey RT, Zacheis D, Brown CW, Nelson EC, Birckbichler PJ, Benbrook DM.
    J Med Chem; 1999 Sep 09; 42(18):3602-14. PubMed ID: 10479291
    [Abstract] [Full Text] [Related]

  • 4. Retinoid signaling is attenuated by proteasome-mediated degradation of retinoid receptors in human keratinocyte HaCaT cells.
    Boudjelal M, Voorhees JJ, Fisher GJ.
    Exp Cell Res; 2002 Mar 10; 274(1):130-7. PubMed ID: 11855864
    [Abstract] [Full Text] [Related]

  • 5. Receptor specificity of retinoid-induced epidermal hyperplasia: effect of RXR-selective agonists and correlation with topical irritation.
    Thacher SM, Standeven AM, Athanikar J, Kopper S, Castilleja O, Escobar M, Beard RL, Chandraratna RA.
    J Pharmacol Exp Ther; 1997 Aug 10; 282(2):528-34. PubMed ID: 9262312
    [Abstract] [Full Text] [Related]

  • 6. Identification of the first retinoid X, receptor homodimer antagonist.
    Canan Koch SS, Dardashti LJ, Hebert JJ, White SK, Croston GE, Flatten KS, Heyman RA, Nadzan AM.
    J Med Chem; 1996 Aug 16; 39(17):3229-34. PubMed ID: 8765503
    [No Abstract] [Full Text] [Related]

  • 7. Effects of retinoid ligands on RIP140: molecular interaction with retinoid receptors and biological activity.
    Farooqui M, Franco PJ, Thompson J, Kagechika H, Chandraratna RA, Banaszak L, Wei LN.
    Biochemistry; 2003 Feb 04; 42(4):971-9. PubMed ID: 12549917
    [Abstract] [Full Text] [Related]

  • 8. Design of selective nuclear receptor modulators: RAR and RXR as a case study.
    de Lera AR, Bourguet W, Altucci L, Gronemeyer H.
    Nat Rev Drug Discov; 2007 Oct 04; 6(10):811-20. PubMed ID: 17906643
    [Abstract] [Full Text] [Related]

  • 9. Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists.
    Géhin M, Vivat V, Wurtz JM, Losson R, Chambon P, Moras D, Gronemeyer H.
    Chem Biol; 1999 Aug 04; 6(8):519-29. PubMed ID: 10421757
    [Abstract] [Full Text] [Related]

  • 10. Conformational effects on retinoid receptor selectivity. 1. Effect of 9-double bond geometry on retinoid X receptor activity.
    Jong L, Lehmann JM, Hobbs PD, Harlev E, Huffman JC, Pfahl M, Dawson MI.
    J Med Chem; 1993 Sep 03; 36(18):2605-13. PubMed ID: 8410972
    [Abstract] [Full Text] [Related]

  • 11. Co-regulator recruitment and the mechanism of retinoic acid receptor synergy.
    Germain P, Iyer J, Zechel C, Gronemeyer H.
    Nature; 2002 Jan 10; 415(6868):187-92. PubMed ID: 11805839
    [Abstract] [Full Text] [Related]

  • 12. Retinoic acid receptor beta,gamma-selective ligands: synthesis and biological activity of 6-substituted 2-naphthoic acid retinoids.
    Yu KL, Spinazze P, Ostrowski J, Currier SJ, Pack EJ, Hammer L, Roalsvig T, Honeyman JA, Tortolani DR, Reczek PR, Mansuri MM, Starrett JE.
    J Med Chem; 1996 Jun 07; 39(12):2411-21. PubMed ID: 8691435
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and structure-activity relationships of stilbene retinoid analogs substituted with heteroaromatic carboxylic acids.
    Beard RL, Chandraratna RA, Colon DF, Gillett SJ, Henry E, Marler DK, Song T, Denys L, Garst ME, Arefieg T.
    J Med Chem; 1995 Jul 21; 38(15):2820-9. PubMed ID: 7636843
    [Abstract] [Full Text] [Related]

  • 14. Corepressor interaction differentiates the permissive and non-permissive retinoid X receptor heterodimers.
    Lammi J, Perlmann T, Aarnisalo P.
    Arch Biochem Biophys; 2008 Apr 15; 472(2):105-14. PubMed ID: 18282463
    [Abstract] [Full Text] [Related]

  • 15. Pyrazine arotinoids with inverse agonist activities on the retinoid and rexinoid receptors.
    García J, Khanwalkar H, Pereira R, Erb C, Voegel JJ, Collette P, Mauvais P, Bourguet W, Gronemeyer H, de Lera AR.
    Chembiochem; 2009 May 04; 10(7):1252-9. PubMed ID: 19343742
    [Abstract] [Full Text] [Related]

  • 16. Derivation of a retinoid X receptor scaffold from peroxisome proliferator-activated receptor gamma ligand 1-Di(1H-indol-3-yl)methyl-4-trifluoromethylbenzene.
    Dawson MI, Ye M, Cao X, Farhana L, Hu QY, Zhao Y, Xu LP, Kiselyuk A, Correa RG, Yang L, Hou T, Reed JC, Itkin-Ansari P, Levine F, Sanner MF, Fontana JA, Zhang XK.
    ChemMedChem; 2009 Jul 04; 4(7):1106-19. PubMed ID: 19378296
    [Abstract] [Full Text] [Related]

  • 17. Agonist and antagonist of retinoic acid receptors cause similar changes in gene expression and induce senescence-like growth arrest in MCF-7 breast carcinoma cells.
    Chen Y, Dokmanovic M, Stein WD, Ardecky RJ, Roninson IB.
    Cancer Res; 2006 Sep 01; 66(17):8749-61. PubMed ID: 16951191
    [Abstract] [Full Text] [Related]

  • 18. Antagonist analogue of 6-[3'-(1-adamantyl)-4'-hydroxyphenyl]-2-naphthalenecarboxylic acid (AHPN) family of apoptosis inducers that effectively blocks AHPN-induced apoptosis but not cell-cycle arrest.
    Dawson MI, Harris DL, Liu G, Hobbs PD, Lange CW, Jong L, Bruey-Sedano N, James SY, Zhang XK, Peterson VJ, Leid M, Farhana L, Rishi AK, Fontana JA.
    J Med Chem; 2004 Jul 01; 47(14):3518-36. PubMed ID: 15214780
    [Abstract] [Full Text] [Related]

  • 19. Retinoid receptor subtype-selective modulators through synthetic modifications of RARgamma agonists.
    Alvarez S, Alvarez R, Khanwalkar H, Germain P, Lemaire G, Rodríguez-Barrios F, Gronemeyer H, de Lera AR.
    Bioorg Med Chem; 2009 Jul 01; 17(13):4345-59. PubMed ID: 19482478
    [Abstract] [Full Text] [Related]

  • 20. RAR/RXR and PPAR/RXR signaling in neurological and psychiatric diseases.
    van Neerven S, Kampmann E, Mey J.
    Prog Neurobiol; 2008 Aug 01; 85(4):433-51. PubMed ID: 18554773
    [Abstract] [Full Text] [Related]


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