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583 related items for PubMed ID: 15317749

  • 1. Reduced hepatic expression of farnesoid X receptor in hereditary cholestasis associated to mutation in ATP8B1.
    Alvarez L, Jara P, Sánchez-Sabaté E, Hierro L, Larrauri J, Díaz MC, Camarena C, De la Vega A, Frauca E, López-Collazo E, Lapunzina P.
    Hum Mol Genet; 2004 Oct 15; 13(20):2451-60. PubMed ID: 15317749
    [Abstract] [Full Text] [Related]

  • 2. Bile salt excretory pump: biology and pathobiology.
    Suchy FJ, Ananthanarayanan M.
    J Pediatr Gastroenterol Nutr; 2006 Jul 15; 43 Suppl 1():S10-6. PubMed ID: 16819395
    [Abstract] [Full Text] [Related]

  • 3. ATP8B1 deficiency disrupts the bile canalicular membrane bilayer structure in hepatocytes, but FXR expression and activity are maintained.
    Cai SY, Gautam S, Nguyen T, Soroka CJ, Rahner C, Boyer JL.
    Gastroenterology; 2009 Mar 15; 136(3):1060-9. PubMed ID: 19027009
    [Abstract] [Full Text] [Related]

  • 4. Progressive familial intrahepatic cholestasis, type 1, is associated with decreased farnesoid X receptor activity.
    Chen F, Ananthanarayanan M, Emre S, Neimark E, Bull LN, Knisely AS, Strautnieks SS, Thompson RJ, Magid MS, Gordon R, Balasubramanian N, Suchy FJ, Shneider BL.
    Gastroenterology; 2004 Mar 15; 126(3):756-64. PubMed ID: 14988830
    [Abstract] [Full Text] [Related]

  • 5. Sequencing of FIC1, BSEP and MDR3 in a large cohort of patients with cholestasis revealed a high number of different genetic variants.
    Dröge C, Bonus M, Baumann U, Klindt C, Lainka E, Kathemann S, Brinkert F, Grabhorn E, Pfister ED, Wenning D, Fichtner A, Gotthardt DN, Weiss KH, McKiernan P, Puri RD, Verma IC, Kluge S, Gohlke H, Schmitt L, Kubitz R, Häussinger D, Keitel V.
    J Hepatol; 2017 Dec 15; 67(6):1253-1264. PubMed ID: 28733223
    [Abstract] [Full Text] [Related]

  • 6. Differences in presentation and progression between severe FIC1 and BSEP deficiencies.
    Pawlikowska L, Strautnieks S, Jankowska I, Czubkowski P, Emerick K, Antoniou A, Wanty C, Fischler B, Jacquemin E, Wali S, Blanchard S, Nielsen IM, Bourke B, McQuaid S, Lacaille F, Byrne JA, van Eerde AM, Kolho KL, Klomp L, Houwen R, Bacchetti P, Lobritto S, Hupertz V, McClean P, Mieli-Vergani G, Shneider B, Nemeth A, Sokal E, Freimer NB, Knisely AS, Rosenthal P, Whitington PF, Pawlowska J, Thompson RJ, Bull LN.
    J Hepatol; 2010 Jul 15; 53(1):170-8. PubMed ID: 20447715
    [Abstract] [Full Text] [Related]

  • 7. The membrane protein ATPase class I type 8B member 1 signals through protein kinase C zeta to activate the farnesoid X receptor.
    Frankenberg T, Miloh T, Chen FY, Ananthanarayanan M, Sun AQ, Balasubramaniyan N, Arias I, Setchell KD, Suchy FJ, Shneider BL.
    Hepatology; 2008 Dec 15; 48(6):1896-905. PubMed ID: 18668687
    [Abstract] [Full Text] [Related]

  • 8. Progressive familial intrahepatic cholestasis.
    Jacquemin E.
    Clin Res Hepatol Gastroenterol; 2012 Sep 15; 36 Suppl 1():S26-35. PubMed ID: 23141890
    [Abstract] [Full Text] [Related]

  • 9. ATP8B1 and ABCB11 analysis in 62 children with normal gamma-glutamyl transferase progressive familial intrahepatic cholestasis (PFIC): phenotypic differences between PFIC1 and PFIC2 and natural history.
    Davit-Spraul A, Fabre M, Branchereau S, Baussan C, Gonzales E, Stieger B, Bernard O, Jacquemin E.
    Hepatology; 2010 May 15; 51(5):1645-55. PubMed ID: 20232290
    [Abstract] [Full Text] [Related]

  • 10. Knockdown of ATP8B1 expression leads to specific downregulation of the bile acid sensor FXR in HepG2 cells: effect of the FXR agonist GW4064.
    Martínez-Fernández P, Hierro L, Jara P, Alvarez L.
    Am J Physiol Gastrointest Liver Physiol; 2009 May 15; 296(5):G1119-29. PubMed ID: 19228886
    [Abstract] [Full Text] [Related]

  • 11. Low retinol levels differentially modulate bile salt-induced expression of human and mouse hepatic bile salt transporters.
    Hoeke MO, Plass JR, Heegsma J, Geuken M, van Rijsbergen D, Baller JF, Kuipers F, Moshage H, Jansen PL, Faber KN.
    Hepatology; 2009 Jan 15; 49(1):151-9. PubMed ID: 19111018
    [Abstract] [Full Text] [Related]

  • 12. [Childhood cholestasis and bile transporters].
    Hierro L, Jara P.
    Gastroenterol Hepatol; 2005 Jan 15; 28(7):388-95. PubMed ID: 16137474
    [Abstract] [Full Text] [Related]

  • 13. [Liver disease associated with hereditary defects of hepatobiliary transporters].
    Wendum D.
    Ann Pathol; 2010 Dec 15; 30(6):426-31. PubMed ID: 21167428
    [Abstract] [Full Text] [Related]

  • 14. Oxysterol 22(R)-hydroxycholesterol induces the expression of the bile salt export pump through nuclear receptor farsenoid X receptor but not liver X receptor.
    Deng R, Yang D, Yang J, Yan B.
    J Pharmacol Exp Ther; 2006 Apr 15; 317(1):317-25. PubMed ID: 16371446
    [Abstract] [Full Text] [Related]

  • 15. Farnesoid X receptor and bile salts are involved in transcriptional regulation of the gene encoding the human bile salt export pump.
    Plass JR, Mol O, Heegsma J, Geuken M, Faber KN, Jansen PL, Müller M.
    Hepatology; 2002 Mar 15; 35(3):589-96. PubMed ID: 11870371
    [Abstract] [Full Text] [Related]

  • 16. NR1H4 analysis in patients with progressive familial intrahepatic cholestasis, drug-induced cholestasis or intrahepatic cholestasis of pregnancy unrelated to ATP8B1, ABCB11 and ABCB4 mutations.
    Davit-Spraul A, Gonzales E, Jacquemin E.
    Clin Res Hepatol Gastroenterol; 2012 Dec 15; 36(6):569-73. PubMed ID: 23142591
    [Abstract] [Full Text] [Related]

  • 17. Genetics and Molecular Modeling of New Mutations of Familial Intrahepatic Cholestasis in a Single Italian Center.
    Giovannoni I, Callea F, Bellacchio E, Torre G, De Ville De Goyet J, Francalanci P.
    PLoS One; 2015 Dec 15; 10(12):e0145021. PubMed ID: 26678486
    [Abstract] [Full Text] [Related]

  • 18. Defective canalicular transport and toxicity of dietary ursodeoxycholic acid in the abcb11-/- mouse: transport and gene expression studies.
    Wang R, Liu L, Sheps JA, Forrest D, Hofmann AF, Hagey LR, Ling V.
    Am J Physiol Gastrointest Liver Physiol; 2013 Aug 15; 305(4):G286-94. PubMed ID: 23764895
    [Abstract] [Full Text] [Related]

  • 19. Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor.
    Ananthanarayanan M, Balasubramanian N, Makishima M, Mangelsdorf DJ, Suchy FJ.
    J Biol Chem; 2001 Aug 03; 276(31):28857-65. PubMed ID: 11387316
    [Abstract] [Full Text] [Related]

  • 20. Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice.
    Wagner M, Fickert P, Zollner G, Fuchsbichler A, Silbert D, Tsybrovskyy O, Zatloukal K, Guo GL, Schuetz JD, Gonzalez FJ, Marschall HU, Denk H, Trauner M.
    Gastroenterology; 2003 Sep 03; 125(3):825-38. PubMed ID: 12949728
    [Abstract] [Full Text] [Related]

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