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101 related items for PubMed ID: 1532139

  • 1. Inactivation and repair of double-stranded DNA damaged by the aziridinyl nitroimidazole RSU 1069.
    Lafleur MV, Westmijze EJ, Visser OJ, Wagenaar N, Soetekouw R, Loman H, Retel J.
    Chem Biol Interact; 1992 Mar; 82(1):55-71. PubMed ID: 1532139
    [Abstract] [Full Text] [Related]

  • 2. Interaction of RSU 1069 and 1137 with DNA in vitro. Biological implications and mechanistic aspects.
    Lafleur MV, Westmijze EJ, Visser OJ, Wagenaar N, Soetekouw R, Loman H, Retèl J.
    Biochem Pharmacol; 1991 Jun 01; 41(11):1649-55. PubMed ID: 1828345
    [Abstract] [Full Text] [Related]

  • 3. Comparative DNA damage and repair induced by misonidazole, CB 1954 and RSU 1069.
    Dale LD, Widdick DA, Edwards DI, Biol GI.
    Int J Radiat Oncol Biol Phys; 1989 Apr 01; 16(4):995-9. PubMed ID: 2649469
    [Abstract] [Full Text] [Related]

  • 4. Effects of sulphydryl compounds on the radiation damage in biologically active DNA.
    Lafleur MV, Woldhuis J, Loman H.
    Int J Radiat Biol Relat Stud Phys Chem Med; 1980 May 01; 37(5):493-8. PubMed ID: 6447117
    [Abstract] [Full Text] [Related]

  • 5. Effects of the ortho-quinone and catechol of the antitumor drug VP-16-213 on the biological activity of single-stranded and double-stranded phi X174 DNA.
    van Maanen JM, Lafleur MV, Mans DR, van den Akker E, de Ruiter C, Kootstra PR, Pappie D, de Vries J, Retèl J, Pinedo HM.
    Biochem Pharmacol; 1988 Oct 01; 37(19):3579-89. PubMed ID: 2972290
    [Abstract] [Full Text] [Related]

  • 6. The repair of DNA damage induced in V79 mammalian cells by the nitroimidazole-aziridine, RSU-1069. Implications for radiosensitization.
    Jenner TJ, O'Neill P, Crump PW, Fielden EM, Sapora O, Santodonato L.
    Biochem Pharmacol; 1991 Oct 09; 42(9):1705-10. PubMed ID: 1930296
    [Abstract] [Full Text] [Related]

  • 7. Enhancement of DNA damage in mammalian cells upon bioreduction of the nitroimidazole-aziridines RSU-1069 and RSU-1131.
    Jenner TJ, Sapora O, O'Neill P, Fielden EM.
    Biochem Pharmacol; 1988 Oct 15; 37(20):3837-42. PubMed ID: 3190731
    [Abstract] [Full Text] [Related]

  • 8. Induction of DNA crosslinks in vitro upon reduction of the nitroimidazole-aziridines RSU-1069 and RSU-1131.
    O'Neill P, McNeil SS, Jenkins TC.
    Biochem Pharmacol; 1987 Jun 01; 36(11):1787-92. PubMed ID: 3579973
    [Abstract] [Full Text] [Related]

  • 9. Assessment of the repair and damage of DNA induced by parent and reduced RSU-1069, a 2-nitroimidazole-aziridine.
    O'Neill P, Cunniffe SM.
    Int J Radiat Oncol Biol Phys; 1989 Apr 01; 16(4):963-6. PubMed ID: 2649467
    [Abstract] [Full Text] [Related]

  • 10. Role of the semi-quinone free radical of the anti-tumour agent etoposide (VP-16-213) in the inactivation of single- and double-stranded phi X174 DNA.
    Mans DR, Retèl J, van Maanen JM, Lafleur MV, van Schaik MA, Pinedo HM, Lankelma J.
    Br J Cancer; 1990 Jul 01; 62(1):54-60. PubMed ID: 2167725
    [Abstract] [Full Text] [Related]

  • 11. Alkali-labile sites and post-irradiation effects in gamma-irradiated biologically active double-stranded DNA in aqueous solution.
    Lafleur MV, Woldhuis J, Loman H.
    Int J Radiat Biol Relat Stud Phys Chem Med; 1979 Sep 01; 36(3):241-7. PubMed ID: 159268
    [Abstract] [Full Text] [Related]

  • 12. Comparative DNA damage induced by nitroimidazole-aziridine drugs: 1. Effects of methyl substitution on drug action.
    Dale LD, Tocher JH, Edwards DI.
    Anticancer Drug Des; 1988 Dec 01; 3(3):169-75. PubMed ID: 3207464
    [Abstract] [Full Text] [Related]

  • 13. Induction of DNA strand breaks by reduced nitroimidazoles. Implications for DNA base damage.
    Silver AR, McNeil SS, O'Neill P, Jenkins TC, Ahmed I.
    Biochem Pharmacol; 1986 Nov 15; 35(22):3923-8. PubMed ID: 3778516
    [Abstract] [Full Text] [Related]

  • 14. Radiation damage to phi X174 DNA and biological effects.
    Lafleur MV, Loman H.
    Radiat Environ Biophys; 1986 Nov 15; 25(3):159-73. PubMed ID: 3025919
    [Abstract] [Full Text] [Related]

  • 15. Processing of model single-strand breaks in phi X-174 RF transfecting DNA by Escherichia coli.
    Kow YW, Faundez G, Melamede RJ, Wallace SS.
    Radiat Res; 1991 Jun 15; 126(3):357-66. PubMed ID: 1852023
    [Abstract] [Full Text] [Related]

  • 16. Excision repair participates in the Weigle reactivation of ultraviolet light-irradiated phi X174 double-stranded DNA.
    Silber JR, Achey PM.
    Mutat Res; 1984 Jan 15; 131(1):1-10. PubMed ID: 6229696
    [Abstract] [Full Text] [Related]

  • 17. Detection of hypoxia by measurement of DNA damage in individual cells from spheroids and murine tumours exposed to bioreductive drugs. II. RSU 1069.
    Olive PL.
    Br J Cancer; 1995 Mar 15; 71(3):537-42. PubMed ID: 7880736
    [Abstract] [Full Text] [Related]

  • 18. The differential cytotoxicity of RSU 1069: cell survival studies indicating interaction with DNA as a possible mode of action.
    Stratford IJ, Walling JM, Silver AR.
    Br J Cancer; 1986 Mar 15; 53(3):339-44. PubMed ID: 3754453
    [Abstract] [Full Text] [Related]

  • 19. DNA damage induced by ascorbate in the presence of Cu2+.
    Kobayashi S, Ueda K, Morita J, Sakai H, Komano T.
    Biochim Biophys Acta; 1988 Jan 25; 949(1):143-7. PubMed ID: 2961370
    [Abstract] [Full Text] [Related]

  • 20. DNA damage by chemically generated singlet oxygen.
    Lafleur MV, Nieuwint AW, Aubry JM, Kortbeek H, Arwert F, Joenje H.
    Free Radic Res Commun; 1987 Jan 25; 2(4-6):343-50. PubMed ID: 2849589
    [Abstract] [Full Text] [Related]

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