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Journal Abstract Search


67 related items for PubMed ID: 15322247

  • 1. Induction of radiosensitization by indolocarbazole derivatives: the role of DNA topoisomerase I.
    Chen AY, Shih SJ, Hsiao M, Rothenberg ML, Prudhomme M.
    Mol Pharmacol; 2004 Sep; 66(3):553-60. PubMed ID: 15322247
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  • 2. Use of camptothecin-resistant mammalian cell lines to evaluate the role of topoisomerase I in the antiproliferative activity of the indolocarbazole, NB-506, and its topoisomerase I binding site.
    Urasaki Y, Laco G, Takebayashi Y, Bailly C, Kohlhagen G, Pommier Y.
    Cancer Res; 2001 Jan 15; 61(2):504-8. PubMed ID: 11212241
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  • 4. Silatecan DB-67 is a novel DNA topoisomerase I-targeted radiation sensitizer.
    Chen AY, Shih SJ, Garriques LN, Rothenberg ML, Hsiao M, Curran DP.
    Mol Cancer Ther; 2005 Feb 15; 4(2):317-24. PubMed ID: 15713902
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  • 5. Enhancement of radiotherapy with DNA topoisomerase I-targeted drugs.
    Chen AY, Chou R, Shih SJ, Lau D, Gandara D.
    Crit Rev Oncol Hematol; 2004 May 15; 50(2):111-9. PubMed ID: 15157660
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  • 7. Indolocarbazole glycosides in inactive conformations.
    Facompré M, Carrasco C, Vezin H, Chisholm JD, Yoburn JC, Van Vranken DL, Bailly C.
    Chembiochem; 2003 May 09; 4(5):386-95. PubMed ID: 12740810
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  • 8. Ku86 modulates DNA topoisomerase I-mediated radiosensitization, but not cytotoxicity, in mammalian cells.
    Shih SJ, Erbele T, Chen AY.
    Cancer Res; 2005 Oct 15; 65(20):9194-9. PubMed ID: 16230379
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  • 9. DNA repair enzyme, O6-methylguanine DNA methyltransferase, modulates cytotoxicity of camptothecin-derived topoisomerase I inhibitors.
    Kuo CC, Liu JF, Chang JY.
    J Pharmacol Exp Ther; 2006 Feb 15; 316(2):946-54. PubMed ID: 16258022
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  • 12. Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex.
    Staker BL, Feese MD, Cushman M, Pommier Y, Zembower D, Stewart L, Burgin AB.
    J Med Chem; 2005 Apr 07; 48(7):2336-45. PubMed ID: 15801827
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  • 13. Induction of mammalian DNA topoisomerase I mediated DNA cleavage by antitumor indolocarbazole derivatives.
    Yamashita Y, Fujii N, Murakata C, Ashizawa T, Okabe M, Nakano H.
    Biochemistry; 1992 Dec 08; 31(48):12069-75. PubMed ID: 1333791
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  • 16. Characterisation of cytotoxicity and DNA damage induced by the topoisomerase II-directed bisdioxopiperazine anti-cancer agent ICRF-187 (dexrazoxane) in yeast and mammalian cells.
    Jensen LH, Dejligbjerg M, Hansen LT, Grauslund M, Jensen PB, Sehested M.
    BMC Pharmacol; 2004 Dec 02; 4():31. PubMed ID: 15575955
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  • 17. Uptake of inorganic and organic derivatives of arsenic associated with induced cytotoxic and genotoxic effects in Chinese hamster ovary (CHO) cells.
    Dopp E, Hartmann LM, Florea AM, von Recklinghausen U, Pieper R, Shokouhi B, Rettenmeier AW, Hirner AV, Obe G.
    Toxicol Appl Pharmacol; 2004 Dec 01; 201(2):156-65. PubMed ID: 15541755
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  • 18. Syntheses and biological activities of rebeccamycin analogues with uncommon sugars.
    Zhang G, Shen J, Cheng H, Zhu L, Fang L, Luo S, Muller MT, Lee GE, Wei L, Du Y, Sun D, Wang PG.
    J Med Chem; 2005 Apr 07; 48(7):2600-11. PubMed ID: 15801850
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  • 19. Design and synthesis of N-methylmaleimide indolocarbazole bearing modified 2-acetamino acid moieties as Topoisomerase I inhibitors.
    Li Z, Zhai F, Zhao L, Guo Q, You Q.
    Bioorg Med Chem Lett; 2009 Jan 15; 19(2):406-9. PubMed ID: 19058964
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  • 20. Design and synthesis of N-(pyridylacryl) amino acid derivatives as potential radiosensitizers against HeLa-S3 cells in vitro.
    Xin J, Hu B, Li Z, Mi FS, Shen Y.
    Yao Xue Xue Bao; 1993 Jan 15; 28(2):97-104. PubMed ID: 7687084
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