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PUBMED FOR HANDHELDS

Journal Abstract Search


176 related items for PubMed ID: 15324877

  • 1.
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  • 2. Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 1.
    Lorthiois E, Bernardelli P, Vergne F, Oliveira C, Mafroud AK, Proust E, Heuze L, Moreau F, Idrissi M, Tertre A, Bertin B, Coupe M, Wrigglesworth R, Descours A, Soulard P, Berna P.
    Bioorg Med Chem Lett; 2004 Sep 20; 14(18):4623-6. PubMed ID: 15324876
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  • 4. Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 1: design, synthesis and structure-activity relationship studies.
    Vergne F, Bernardelli P, Lorthiois E, Pham N, Proust E, Oliveira C, Mafroud AK, Royer F, Wrigglesworth R, Schellhaas J, Barvian M, Moreau F, Idrissi M, Tertre A, Bertin B, Coupe M, Berna P, Soulard P.
    Bioorg Med Chem Lett; 2004 Sep 20; 14(18):4607-13. PubMed ID: 15324874
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  • 5. Fused pyrimidine based inhibitors of phosphodiesterase 7 (PDE7): synthesis and initial structure-activity relationships.
    Kempson J, Pitts WJ, Barbosa J, Guo J, Omotoso O, Watson A, Stebbins K, Starling GC, Dodd JH, Barrish JC, Felix R, Fischer K.
    Bioorg Med Chem Lett; 2005 Apr 01; 15(7):1829-33. PubMed ID: 15780616
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  • 7. Substituted 2-pyridinemethanol derivatives as potent and selective phosphodiesterase-4 inhibitors.
    Ducharme Y, Friesen RW, Blouin M, Côté B, Dubé D, Ethier D, Frenette R, Laliberté F, Mancini JA, Masson P, Styhler A, Young RN, Girard Y.
    Bioorg Med Chem Lett; 2003 Jun 02; 13(11):1923-6. PubMed ID: 12749899
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  • 10. Cyclic nucleotide phosphodiesterases (PDEs) in human osteoblastic cells; the effect of PDE inhibition on cAMP accumulation.
    Ahlström M, Pekkinen M, Huttunen M, Lamberg-Allardt C.
    Cell Mol Biol Lett; 2005 Jun 02; 10(2):305-19. PubMed ID: 16010295
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  • 13. Identification of purine inhibitors of phosphodiesterase 7 (PDE7).
    Pitts WJ, Vaccaro W, Huynh T, Leftheris K, Roberge JY, Barbosa J, Guo J, Brown B, Watson A, Donaldson K, Starling GC, Kiener PA, Poss MA, Dodd JH, Barrish JC.
    Bioorg Med Chem Lett; 2004 Jun 07; 14(11):2955-8. PubMed ID: 15125967
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  • 14. Orally active PDE4 inhibitors with therapeutic potential.
    Ochiai H, Ohtani T, Ishida A, Kishikawa K, Obata T, Nakai H, Toda M.
    Bioorg Med Chem Lett; 2004 Mar 08; 14(5):1323-7. PubMed ID: 14980691
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  • 15. Phosphodiesterase 4 regulation of cyclic AMP in pulmonary remodelling: potential roles for isoform selective inhibitors.
    Shepherd MC.
    Pulm Pharmacol Ther; 2006 Mar 08; 19(1):24-31. PubMed ID: 16046159
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  • 17. Synthesis, biological evaluation and molecular modelling studies on benzothiadiazine derivatives as PDE4 selective inhibitors.
    Tait A, Luppi A, Hatzelmann A, Fossa P, Mosti L.
    Bioorg Med Chem; 2005 Feb 15; 13(4):1393-402. PubMed ID: 15670947
    [Abstract] [Full Text] [Related]

  • 18. Inhibitory effects of flavonoids on phosphodiesterase isozymes from guinea pig and their structure-activity relationships.
    Ko WC, Shih CM, Lai YH, Chen JH, Huang HL.
    Biochem Pharmacol; 2004 Nov 15; 68(10):2087-94. PubMed ID: 15476679
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