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Journal Abstract Search


334 related items for PubMed ID: 15324909

  • 21. Effect of A-ring modifications on the DNA-binding behavior and cytotoxicity of pyrrolo[2,1-c][1,4]benzodiazepines.
    Thurston DE, Bose DS, Howard PW, Jenkins TC, Leoni A, Baraldi PG, Guiotto A, Cacciari B, Kelland LR, Foloppe MP, Rault S.
    J Med Chem; 1999 Jun 03; 42(11):1951-64. PubMed ID: 10354403
    [Abstract] [Full Text] [Related]

  • 22. Pyrrolo[2,1-c][1,4]benzodiazepine-anthraquinone conjugates. Synthesis, DNA binding and cytotoxicity.
    Kamal A, Ramu R, Khanna GB, Saxena AK, Shanmugavel M, Pandita RM.
    Bioorg Med Chem Lett; 2004 Oct 04; 14(19):4907-9. PubMed ID: 15341949
    [Abstract] [Full Text] [Related]

  • 23. Synthesis and DNA-binding ability of pyrrolo[2,1-c][1,4]benzodiazepine-azepane conjugates.
    Kamal A, Reddy DR, Reddy PS, Rajendar.
    Bioorg Med Chem Lett; 2006 Mar 01; 16(5):1160-3. PubMed ID: 16361097
    [Abstract] [Full Text] [Related]

  • 24. Remarkable enhancement in the DNA-binding ability of C2-fluoro substituted pyrrolo[2,1-c][1,4]benzodiazepines and their anticancer potential.
    Kamal A, Rajender, Reddy DR, Reddy MK, Balakishan G, Shaik TB, Chourasia M, Sastry GN.
    Bioorg Med Chem; 2009 Feb 15; 17(4):1557-72. PubMed ID: 19168361
    [Abstract] [Full Text] [Related]

  • 25. Dithiocarbamate/piperazine bridged pyrrolobenzodiazepines as DNA-minor groove binders: synthesis, DNA-binding affinity and cytotoxic activity.
    Kamal A, Sreekanth K, Shankaraiah N, Sathish M, Nekkanti S, Srinivasulu V.
    Bioorg Chem; 2015 Apr 15; 59():23-30. PubMed ID: 25665519
    [Abstract] [Full Text] [Related]

  • 26. Synthesis and DNA-binding affinity of A-C8/C-C2 alkoxyamido-linked pyrrolo[2,1-c][1,4]benzodiazepine dimers.
    Kamal A, Ramulu P, Srinivas O, Ramesh G.
    Bioorg Med Chem Lett; 2003 Nov 17; 13(22):3955-8. PubMed ID: 14592483
    [Abstract] [Full Text] [Related]

  • 27. Remarkable DNA binding affinity and potential anticancer activity of pyrrolo[2,1-c][1,4]benzodiazepine-naphthalimide conjugates linked through piperazine side-armed alkane spacers.
    Kamal A, Ramu R, Tekumalla V, Khanna GB, Barkume MS, Juvekar AS, Zingde SM.
    Bioorg Med Chem; 2008 Aug 01; 16(15):7218-24. PubMed ID: 18656370
    [Abstract] [Full Text] [Related]

  • 28. An asymmetric C8/C8'-tripyrrole-linked sequence-selective pyrrolo[2,1-c][1,4]benzodiazepine (PBD) dimer DNA interstrand cross-linking agent spanning 11 DNA base pairs.
    Tiberghien AC, Evans DA, Kiakos K, Martin CR, Hartley JA, Thurston DE, Howard PW.
    Bioorg Med Chem Lett; 2008 Mar 15; 18(6):2073-7. PubMed ID: 18272367
    [Abstract] [Full Text] [Related]

  • 29. Synthesis and biological evaluation of estradiol linked pyrrolo[2,1-c][1,4]benzodiazepine (PBD) conjugates as potential anticancer agents.
    Kamal A, Reddy MK, Ramaiah MJ, Rajender, Reddy JS, Srikanth YV, Dastagiri D, Bharathi EV, Pushpavalli SN, Sarma P, Pal-Bhadra M.
    Bioorg Med Chem; 2011 Apr 15; 19(8):2565-81. PubMed ID: 21459581
    [Abstract] [Full Text] [Related]

  • 30. Fluorescent 7-diethylaminocoumarin pyrrolobenzodiazepine conjugates: synthesis, DNA interaction, cytotoxicity and differential cellular localization.
    Wells G, Suggitt M, Coffils M, Baig MA, Howard PW, Loadman PM, Hartley JA, Jenkins TC, Thurston DE.
    Bioorg Med Chem Lett; 2008 Mar 15; 18(6):2147-51. PubMed ID: 18280154
    [Abstract] [Full Text] [Related]

  • 31. Synthesis, anticancer activity and apoptosis inducing ability of anthranilamide-PBD conjugates.
    Kamal A, Vijaya Bharathi E, Janaki Ramaiah M, Surendranadha Reddy J, Dastagiri D, Viswanath A, Sultana F, Pushpavalli SN, Pal-Bhadra M, Juvekar A, Sen S, Zingde S.
    Bioorg Med Chem Lett; 2010 Jun 01; 20(11):3310-3. PubMed ID: 20444601
    [Abstract] [Full Text] [Related]

  • 32. Synthesis and in vitro cytotoxic evaluation of some thiazolylbenzimidazole derivatives.
    Luo Y, Xiao F, Qian S, Lu W, Yang B.
    Eur J Med Chem; 2011 Jan 01; 46(1):417-22. PubMed ID: 21115212
    [Abstract] [Full Text] [Related]

  • 33. Synthesis and docking studies of novel antitumor benzimidazoles.
    Omar MA, Shaker YM, Galal SA, Ali MM, Kerwin SM, Li J, Tokuda H, Ramadan RA, El Diwani HI.
    Bioorg Med Chem; 2012 Dec 15; 20(24):6989-7001. PubMed ID: 23123017
    [Abstract] [Full Text] [Related]

  • 34. Design, synthesis and biological evaluation of 3,5-diaryl-isoxazoline/isoxazole-pyrrolobenzodiazepine conjugates as potential anticancer agents.
    Kamal A, Reddy JS, Ramaiah MJ, Dastagiri D, Bharathi EV, Azhar MA, Sultana F, Pushpavalli SN, Pal-Bhadra M, Juvekar A, Sen S, Zingde S.
    Eur J Med Chem; 2010 Sep 15; 45(9):3924-37. PubMed ID: 20557981
    [Abstract] [Full Text] [Related]

  • 35. Design, synthesis and in vitro cytotoxicity studies of novel pyrrolo[2,1-c][1,4]benzodiazepine (PBD)--polymade conjugates and 2,2'-PBD dimers.
    Reddy BS, Damayanthi Y, Reddy BS, Lown JW.
    Anticancer Drug Des; 2000 Jun 15; 15(3):225-38. PubMed ID: 11049090
    [Abstract] [Full Text] [Related]

  • 36.
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  • 37. Recent developments in novel pyrrolo[2,1-c][1,4]benzodiazepine conjugates: synthesis and biological evaluation.
    Kumar R, Lown JW.
    Mini Rev Med Chem; 2003 Jun 15; 3(4):323-39. PubMed ID: 12678826
    [Abstract] [Full Text] [Related]

  • 38. Design, synthesis, and evaluation of a novel sequence-selective epoxide-containing DNA cross-linking agent based on the pyrrolo[2, 1-c][1,4]benzodiazepine system.
    Wilson SC, Howard PW, Forrow SM, Hartley JA, Adams LJ, Jenkins TC, Kelland LR, Thurston DE.
    J Med Chem; 1999 Oct 07; 42(20):4028-41. PubMed ID: 10514273
    [Abstract] [Full Text] [Related]

  • 39. Pyrrolobenzimidazoles linked to heterocycles and peptides. Design of DNA base pair specific phosphate hydrolyzing agents and novel cytotoxic agents.
    Ghodousi A, Huang X, Cheng Z, Skibo EB.
    J Med Chem; 2004 Jan 01; 47(1):90-100. PubMed ID: 14695823
    [Abstract] [Full Text] [Related]

  • 40. Acenaphtho[1,2-b]pyrrole derivatives as new family of intercalators: various DNA binding geometry and interesting antitumor capacity.
    Zhang Z, Yang Y, Zhang D, Wang Y, Qian X, Liu F.
    Bioorg Med Chem; 2006 Oct 15; 14(20):6962-70. PubMed ID: 16828559
    [Abstract] [Full Text] [Related]


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