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Journal Abstract Search

157 related items for PubMed ID: 15328083

  • 1. The melaminophenyl arsenicals melarsoprol and melarsen oxide interfere with thiamine metabolism in the fission yeast Schizosaccharomyces pombe.
    Schweingruber ME.
    Antimicrob Agents Chemother; 2004 Sep; 48(9):3268-71. PubMed ID: 15328083
    [Abstract] [Full Text] [Related]

  • 2. Biosynthesis and uptake of thiamine (vitamin B1) in bloodstream form Trypanosoma brucei brucei and interference of the vitamin with melarsen oxide activity.
    Stoffel SA, Rodenko B, Schweingruber AM, Mäser P, de Koning HP, Schweingruber ME.
    Int J Parasitol; 2006 Feb; 36(2):229-36. PubMed ID: 16375907
    [Abstract] [Full Text] [Related]

  • 3. Differential sensitivity of Trypanosoma brucei rhodesiense isolates to in vitro lysis by arsenicals.
    Yarlett N, Goldberg B, Nathan HC, Garofalo J, Bacchi CJ.
    Exp Parasitol; 1991 Feb; 72(2):205-15. PubMed ID: 1849084
    [Abstract] [Full Text] [Related]

  • 4. The antitrypanosomal drug melarsoprol competitively inhibits thiamin uptake in mouse neuroblastoma cells.
    Szyniarowski P, Bettendorff L, Schweingruber ME.
    Cell Biol Toxicol; 2006 May; 22(3):183-7. PubMed ID: 16555002
    [Abstract] [Full Text] [Related]

  • 5. Arsenical-resistant trypanosomes lack an unusual adenosine transporter.
    Carter NS, Fairlamb AH.
    Nature; 1993 Jan 14; 361(6408):173-6. PubMed ID: 8421523
    [Abstract] [Full Text] [Related]

  • 6. The role of Trypanosoma brucei MRPA in melarsoprol susceptibility.
    Alibu VP, Richter C, Voncken F, Marti G, Shahi S, Renggli CK, Seebeck T, Brun R, Clayton C.
    Mol Biochem Parasitol; 2006 Mar 14; 146(1):38-44. PubMed ID: 16343658
    [Abstract] [Full Text] [Related]

  • 7. Trypanosoma brucei: lack of cross-resistance to melarsoprol in vitro by cymelarsan-resistant parasites.
    Scott AG, Tait A, Turner CM.
    Exp Parasitol; 1997 Jul 14; 86(3):181-90. PubMed ID: 9225768
    [Abstract] [Full Text] [Related]

  • 8. Characterisation of melarsen-resistant Trypanosoma brucei brucei with respect to cross-resistance to other drugs and trypanothione metabolism.
    Fairlamb AH, Carter NS, Cunningham M, Smith K.
    Mol Biochem Parasitol; 1992 Jul 14; 53(1-2):213-22. PubMed ID: 1501641
    [Abstract] [Full Text] [Related]

  • 9.
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    [No Abstract] [Full Text] [Related]

  • 10. Amiloride toxicity in the fission yeast Schizosaccharomyces pombe is released by thiamine and mutations in the thiamine-repressible gene car1.
    Niederberger C, Fankhauser H, Edenharter E, Schweingruber ME.
    Gene; 1996 May 24; 171(1):119-22. PubMed ID: 8675019
    [Abstract] [Full Text] [Related]

  • 11. Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei.
    Matovu E, Stewart ML, Geiser F, Brun R, Mäser P, Wallace LJ, Burchmore RJ, Enyaru JC, Barrett MP, Kaminsky R, Seebeck T, de Koning HP.
    Eukaryot Cell; 2003 Oct 24; 2(5):1003-8. PubMed ID: 14555482
    [Abstract] [Full Text] [Related]

  • 12. Investigation of the biotransformation of melarsoprol by electrochemistry coupled to complementary LC/ESI-MS and LC/ICP-MS analysis.
    Baumann A, Pfeifer T, Melles D, Karst U.
    Anal Bioanal Chem; 2013 Jun 24; 405(15):5249-58. PubMed ID: 23552974
    [Abstract] [Full Text] [Related]

  • 13. Detection of arsenical drug resistance in Trypanosoma brucei with a simple fluorescence test.
    Stewart ML, Krishna S, Burchmore RJ, Brun R, de Koning HP, Boykin DW, Tidwell RR, Hall JE, Barrett MP.
    Lancet; 2013 Jun 24; 366(9484):486-7. PubMed ID: 16084257
    [Abstract] [Full Text] [Related]

  • 14. Determination of the trypanocidal drug melarsoprol and its conversion products in biological fluids with HPLC-ICPMS/ESMS.
    Raber G, Raber T, Raml R, Murko M, Magnes C, Francesconi KA.
    Talanta; 2013 Nov 15; 116():876-81. PubMed ID: 24148488
    [Abstract] [Full Text] [Related]

  • 15. Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs.
    Munday JC, Eze AA, Baker N, Glover L, Clucas C, Aguinaga Andrés D, Natto MJ, Teka IA, McDonald J, Lee RS, Graf FE, Ludin P, Burchmore RJ, Turner CM, Tait A, MacLeod A, Mäser P, Barrett MP, Horn D, De Koning HP.
    J Antimicrob Chemother; 2014 Mar 15; 69(3):651-63. PubMed ID: 24235095
    [Abstract] [Full Text] [Related]

  • 16. [Melarsoprol].
    Simon F.
    Med Trop (Mars); 1999 Mar 15; 59(4):331-2. PubMed ID: 10816741
    [No Abstract] [Full Text] [Related]

  • 17. Genotypic and phenotypic characterization of Trypanosoma brucei gambiense isolates from Ibba, South Sudan, an area of high melarsoprol treatment failure rate.
    Maina N, Maina KJ, Mäser P, Brun R.
    Acta Trop; 2007 Mar 15; 104(2-3):84-90. PubMed ID: 17765860
    [Abstract] [Full Text] [Related]

  • 18. Characterisation of cloned lines of Trypanosoma brucei expressing stable resistance to MelCy and suramin.
    Scott AG, Tait A, Turner CM.
    Acta Trop; 1996 Feb 15; 60(4):251-62. PubMed ID: 8659324
    [Abstract] [Full Text] [Related]

  • 19. Further evidence for a link between melarsoprol resistance and P2 transporter function in African trypanosomes.
    de Koning HP, MacLeod A, Barrett MP, Cover B, Jarvis SM.
    Mol Biochem Parasitol; 2000 Feb 25; 106(1):181-5. PubMed ID: 10743623
    [No Abstract] [Full Text] [Related]

  • 20. Overexpression of the putative thiol conjugate transporter TbMRPA causes melarsoprol resistance in Trypanosoma brucei.
    Shahi SK, Krauth-Siegel RL, Clayton CE.
    Mol Microbiol; 2002 Mar 25; 43(5):1129-38. PubMed ID: 11918801
    [Abstract] [Full Text] [Related]

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