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165 related items for PubMed ID: 15328341

  • 1. Solution structure of the flexible class II ubiquitin-conjugating enzyme Ubc1 provides insights for polyubiquitin chain assembly.
    Merkley N, Shaw GS.
    J Biol Chem; 2004 Nov 05; 279(45):47139-47. PubMed ID: 15328341
    [Abstract] [Full Text] [Related]

  • 2. Ubiquitin manipulation by an E2 conjugating enzyme using a novel covalent intermediate.
    Merkley N, Barber KR, Shaw GS.
    J Biol Chem; 2005 Sep 09; 280(36):31732-8. PubMed ID: 16014632
    [Abstract] [Full Text] [Related]

  • 3. The HIP2~ubiquitin conjugate forms a non-compact monomeric thioester during di-ubiquitin synthesis.
    Cook BW, Barber KR, Shilton BH, Shaw GS.
    PLoS One; 2015 Sep 09; 10(3):e0120318. PubMed ID: 25799589
    [Abstract] [Full Text] [Related]

  • 4. An E2 accessory domain increases affinity for the anaphase-promoting complex and ensures E2 competition.
    Girard JR, Tenthorey JL, Morgan DO.
    J Biol Chem; 2015 Oct 02; 290(40):24614-25. PubMed ID: 26306044
    [Abstract] [Full Text] [Related]

  • 5. The E2-25K ubiquitin-associated (UBA) domain aids in polyubiquitin chain synthesis and linkage specificity.
    Wilson RC, Edmondson SP, Flatt JW, Helms K, Twigg PD.
    Biochem Biophys Res Commun; 2011 Feb 25; 405(4):662-6. PubMed ID: 21281599
    [Abstract] [Full Text] [Related]

  • 6. The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63-branched ubiquitin chains.
    Pluska L, Jarosch E, Zauber H, Kniss A, Waltho A, Bagola K, von Delbrück M, Löhr F, Schulman BA, Selbach M, Dötsch V, Sommer T.
    EMBO J; 2021 Mar 15; 40(6):e106094. PubMed ID: 33576509
    [Abstract] [Full Text] [Related]

  • 7. Catalysis of lysine 48-specific ubiquitin chain assembly by residues in E2 and ubiquitin.
    Rodrigo-Brenni MC, Foster SA, Morgan DO.
    Mol Cell; 2010 Aug 27; 39(4):548-59. PubMed ID: 20797627
    [Abstract] [Full Text] [Related]

  • 8. Interaction of the tail with the catalytic region of a class II E2 conjugating enzyme.
    Merkley N, Shaw GS.
    J Biomol NMR; 2003 Jun 27; 26(2):147-55. PubMed ID: 12766410
    [Abstract] [Full Text] [Related]

  • 9. The N-terminal extension of UBE2E ubiquitin-conjugating enzymes limits chain assembly.
    Schumacher FR, Wilson G, Day CL.
    J Mol Biol; 2013 Nov 15; 425(22):4099-111. PubMed ID: 23871895
    [Abstract] [Full Text] [Related]

  • 10. Characterization of the chimeric protein cUBC1 engineered by substituting the linker of E2-25K into UBC1 enzyme of Saccharomyces cerevisiae.
    Raimalani V, Panchamia B, Prabha CR.
    Int J Biol Macromol; 2022 Jun 01; 209(Pt A):991-1000. PubMed ID: 35429515
    [Abstract] [Full Text] [Related]

  • 11. Structure and function of ubiquitin conjugating enzyme E2-25K: the tail is a core-dependent activity element.
    Haldeman MT, Xia G, Kasperek EM, Pickart CM.
    Biochemistry; 1997 Aug 26; 36(34):10526-37. PubMed ID: 9265633
    [Abstract] [Full Text] [Related]

  • 12. Solution conformation of Lys63-linked di-ubiquitin chain provides clues to functional diversity of polyubiquitin signaling.
    Varadan R, Assfalg M, Haririnia A, Raasi S, Pickart C, Fushman D.
    J Biol Chem; 2004 Feb 20; 279(8):7055-63. PubMed ID: 14645257
    [Abstract] [Full Text] [Related]

  • 13. C-Terminal acidic domain of ubiquitin-conjugating enzymes: a multi-functional conserved intrinsically disordered domain in family 3 of E2 enzymes.
    Arrigoni A, Grillo B, Vitriolo A, De Gioia L, Papaleo E.
    J Struct Biol; 2012 Jun 20; 178(3):245-59. PubMed ID: 22507829
    [Abstract] [Full Text] [Related]

  • 14. Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail.
    Hamilton KS, Ellison MJ, Barber KR, Williams RS, Huzil JT, McKenna S, Ptak C, Glover M, Shaw GS.
    Structure; 2001 Oct 20; 9(10):897-904. PubMed ID: 11591345
    [Abstract] [Full Text] [Related]

  • 15. Core domain mutation (S86Y) selectively inactivates polyubiquitin chain synthesis catalyzed by E2-25K.
    Mastrandrea LD, Kasperek EM, Niles EG, Pickart CM.
    Biochemistry; 1998 Jul 07; 37(27):9784-92. PubMed ID: 9657692
    [Abstract] [Full Text] [Related]

  • 16. Sequential E2s drive polyubiquitin chain assembly on APC targets.
    Rodrigo-Brenni MC, Morgan DO.
    Cell; 2007 Jul 13; 130(1):127-39. PubMed ID: 17632060
    [Abstract] [Full Text] [Related]

  • 17. Cloning of a 16-kDa ubiquitin carrier protein from wheat and Arabidopsis thaliana. Identification of functional domains by in vitro mutagenesis.
    Sullivan ML, Vierstra RD.
    J Biol Chem; 1991 Dec 15; 266(35):23878-85. PubMed ID: 1660887
    [Abstract] [Full Text] [Related]

  • 18. Crystal structure of the Ube2K/E2-25K and K48-linked di-ubiquitin complex provides structural insight into the mechanism of K48-specific ubiquitin chain synthesis.
    Lee JG, Youn HS, Kang JY, Park SY, Kidera A, Yoo YJ, Eom SH.
    Biochem Biophys Res Commun; 2018 Nov 17; 506(1):102-107. PubMed ID: 30336976
    [Abstract] [Full Text] [Related]

  • 19. Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation.
    Eddins MJ, Carlile CM, Gomez KM, Pickart CM, Wolberger C.
    Nat Struct Mol Biol; 2006 Oct 17; 13(10):915-20. PubMed ID: 16980971
    [Abstract] [Full Text] [Related]

  • 20. Architecture of the catalytic HPN motif is conserved in all E2 conjugating enzymes.
    Cook BW, Shaw GS.
    Biochem J; 2012 Jul 15; 445(2):167-74. PubMed ID: 22563859
    [Abstract] [Full Text] [Related]

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