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184 related items for PubMed ID: 15334055

  • 1. The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathway.
    Vasilcanu D, Girnita A, Girnita L, Vasilcanu R, Axelson M, Larsson O.
    Oncogene; 2004 Oct 14; 23(47):7854-62. PubMed ID: 15334055
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  • 2. Insulin-like growth factor type-I receptor-dependent phosphorylation of extracellular signal-regulated kinase 1/2 but not Akt (protein kinase B) can be induced by picropodophyllin.
    Vasilcanu R, Vasilcanu D, Sehat B, Yin S, Girnita A, Axelson M, Girnita L.
    Mol Pharmacol; 2008 Mar 14; 73(3):930-9. PubMed ID: 18070930
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  • 3. Picropodophyllin inhibits proliferation and survival of diffuse large B-cell lymphoma cells.
    Strömberg T, Feng X, Delforoush M, Berglund M, Lin Y, Axelson M, Larsson O, Georgii-Hemming P, Lennartsson J, Enblad G.
    Med Oncol; 2015 Jul 14; 32(7):188. PubMed ID: 26021470
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  • 4. IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces G2/M-phase accumulation and apoptosis in multiple myeloma cells.
    Strömberg T, Ekman S, Girnita L, Dimberg LY, Larsson O, Axelson M, Lennartsson J, Hellman U, Carlson K, Osterborg A, Vanderkerken K, Nilsson K, Jernberg-Wiklund H.
    Blood; 2006 Jan 15; 107(2):669-78. PubMed ID: 16166596
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  • 9. The luteinizing hormone-releasing hormone inhibits the anti-apoptotic activity of insulin-like growth factor-1 in pituitary alphaT3 cells by protein kinase Calpha-mediated negative regulation of Akt.
    Rose A, Froment P, Perrot V, Quon MJ, LeRoith D, Dupont J.
    J Biol Chem; 2004 Dec 10; 279(50):52500-16. PubMed ID: 15448167
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  • 11. The insulin-like growth factor-I receptor inhibitor picropodophyllin-induced selective apoptosis of hepatocellular carcinoma cell through a caspase-dependent mitochondrial pathway.
    E C, Li J, Shao D, Zhang D, Pan Y, Chen L, Zhang X.
    Oncol Res; 2013 Dec 10; 21(2):103-10. PubMed ID: 24406046
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  • 13. Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.
    Batty IH, Fleming IN, Downes CP.
    Biochem J; 2004 May 01; 379(Pt 3):641-51. PubMed ID: 14769130
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  • 14. Picropodophyllin inhibits type I endometrial cancer cell proliferation via disruption of the PI3K/Akt pathway.
    Dong L, Du M, Lv Q.
    Acta Biochim Biophys Sin (Shanghai); 2019 Jul 10; 51(7):753-760. PubMed ID: 31168597
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  • 15. RACK1 is an insulin-like growth factor 1 (IGF-1) receptor-interacting protein that can regulate IGF-1-mediated Akt activation and protection from cell death.
    Kiely PA, Sant A, O'Connor R.
    J Biol Chem; 2002 Jun 21; 277(25):22581-9. PubMed ID: 11964397
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  • 16. Insulin rescues retinal neurons from apoptosis by a phosphatidylinositol 3-kinase/Akt-mediated mechanism that reduces the activation of caspase-3.
    Barber AJ, Nakamura M, Wolpert EB, Reiter CE, Seigel GM, Antonetti DA, Gardner TW.
    J Biol Chem; 2001 Aug 31; 276(35):32814-21. PubMed ID: 11443130
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  • 18. Phosphatidylinositol 3-kinase (PI-3K)/Akt but not PI-3K/p70 S6 kinase signaling mediates IGF-1-promoted lens epithelial cell survival.
    Chandrasekher G, Sailaja D.
    Invest Ophthalmol Vis Sci; 2004 Oct 31; 45(10):3577-88. PubMed ID: 15452065
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  • 20. Insulin growth factor 1 receptor/PI3K/AKT survival pathway in outer segment membranes of rod photoreceptors.
    Dilly AK, Rajala RV.
    Invest Ophthalmol Vis Sci; 2008 Nov 31; 49(11):4765-73. PubMed ID: 18566464
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