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152 related items for PubMed ID: 1533410

  • 1. Humanized OKT3 antibodies: successful transfer of immune modulating properties and idiotype expression.
    Woodle ES, Thistlethwaite JR, Jolliffe LK, Zivin RA, Collins A, Adair JR, Bodmer M, Athwal D, Alegre ML, Bluestone JA.
    J Immunol; 1992 May 01; 148(9):2756-63. PubMed ID: 1533410
    [Abstract] [Full Text] [Related]

  • 2. Effect of a single amino acid mutation on the activating and immunosuppressive properties of a "humanized" OKT3 monoclonal antibody.
    Alegre ML, Collins AM, Pulito VL, Brosius RA, Olson WC, Zivin RA, Knowles R, Thistlethwaite JR, Jolliffe LK, Bluestone JA.
    J Immunol; 1992 Jun 01; 148(11):3461-8. PubMed ID: 1534096
    [Abstract] [Full Text] [Related]

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  • 4. Anti-CD3 monoclonal antibody therapy. An approach toward optimization by in vitro analysis of new anti-CD3 antibodies.
    Woodle ES, Thistlethwaite JR, Jolliffe LK, Fucello AJ, Stuart FP, Bluestone JA.
    Transplantation; 1991 Aug 01; 52(2):361-8. PubMed ID: 1714644
    [Abstract] [Full Text] [Related]

  • 5. Human IgG2 variants of chimeric anti-CD3 are nonmitogenic to T cells.
    Cole MS, Anasetti C, Tso JY.
    J Immunol; 1997 Oct 01; 159(7):3613-21. PubMed ID: 9317161
    [Abstract] [Full Text] [Related]

  • 6. Construction and characterization of a humanized anti-human CD3 monoclonal antibody 12F6 with effective immunoregulation functions.
    Li B, Wang H, Dai J, Ji J, Qian W, Zhang D, Hou S, Guo Y.
    Immunology; 2005 Dec 01; 116(4):487-98. PubMed ID: 16313362
    [Abstract] [Full Text] [Related]

  • 7. Engineering a humanized bispecific F(ab')2 fragment for improved binding to T cells.
    Rodrigues ML, Shalaby MR, Werther W, Presta L, Carter P.
    Int J Cancer Suppl; 1992 Dec 01; 7():45-50. PubMed ID: 1428403
    [Abstract] [Full Text] [Related]

  • 8. Identification of heavy chain residues in a humanized anti-CD3 antibody important for efficient antigen binding and T cell activation.
    Zhu Z, Carter P.
    J Immunol; 1995 Aug 15; 155(4):1903-10. PubMed ID: 7636241
    [Abstract] [Full Text] [Related]

  • 9. OKT3 F(ab')2 fragments--retention of the immunosuppressive properties of whole antibody with marked reduction in T cell activation and lymphokine release.
    Woodle ES, Thistlethwaite JR, Ghobrial IA, Jolliffe LK, Stuart FP, Bluestone JA.
    Transplantation; 1991 Aug 15; 52(2):354-60. PubMed ID: 1908148
    [Abstract] [Full Text] [Related]

  • 10. Differential effects of a murine and chimeric mouse/human anti-interleukin-2 receptor antibody on human T-cell proliferation.
    Rose B, Gillespie A, Wunderlich D, Kelley K, Dzuiba J, Shedd D, Cahill K, Zerler B.
    Immunology; 1992 Jul 15; 76(3):452-9. PubMed ID: 1526654
    [Abstract] [Full Text] [Related]

  • 11. A non-activating "humanized" anti-CD3 monoclonal antibody retains immunosuppressive properties in vivo.
    Alegre ML, Peterson LJ, Xu D, Sattar HA, Jeyarajah DR, Kowalkowski K, Thistlethwaite JR, Zivin RA, Jolliffe L, Bluestone JA.
    Transplantation; 1994 Jun 15; 57(11):1537-43. PubMed ID: 8009586
    [Abstract] [Full Text] [Related]

  • 12. In vitro characterization of five humanized OKT3 effector function variant antibodies.
    Xu D, Alegre ML, Varga SS, Rothermel AL, Collins AM, Pulito VL, Hanna LS, Dolan KP, Parren PW, Bluestone JA, Jolliffe LK, Zivin RA.
    Cell Immunol; 2000 Feb 25; 200(1):16-26. PubMed ID: 10716879
    [Abstract] [Full Text] [Related]

  • 13. SDR grafting of a murine antibody using multiple human germline templates to minimize its immunogenicity.
    Gonzales NR, Padlan EA, De Pascalis R, Schuck P, Schlom J, Kashmiri SV.
    Mol Immunol; 2004 Jul 25; 41(9):863-72. PubMed ID: 15261458
    [Abstract] [Full Text] [Related]

  • 14. An anti-murine CD3 monoclonal antibody with a low affinity for Fc gamma receptors suppresses transplantation responses while minimizing acute toxicity and immunogenicity.
    Alegre ML, Tso JY, Sattar HA, Smith J, Desalle F, Cole M, Bluestone JA.
    J Immunol; 1995 Aug 01; 155(3):1544-55. PubMed ID: 7636216
    [Abstract] [Full Text] [Related]

  • 15. Immunosuppressive properties of anti-CD3 single-chain Fv and diabody.
    Le Gall F, Reusch U, Moldenhauer G, Little M, Kipriyanov SM.
    J Immunol Methods; 2004 Feb 01; 285(1):111-27. PubMed ID: 14871540
    [Abstract] [Full Text] [Related]

  • 16. Distinct regulatory effects of IL-4 and TNF-alpha during CD3-dependent and CD3-independent initiation of human T-cell activation.
    Damle NK, Doyle LV.
    Lymphokine Res; 1989 Feb 01; 8(2):85-97. PubMed ID: 2525210
    [Abstract] [Full Text] [Related]

  • 17. Novel humanized anti-CD3 antibodies induce a predominantly immunoregulatory profile in human peripheral blood mononuclear cells.
    Silva HM, Vieira PM, Costa PL, Pimentel BM, Moro AM, Kalil J, Maranhão AQ, Coelho V, Brigido MM.
    Immunol Lett; 2009 Aug 15; 125(2):129-36. PubMed ID: 19573559
    [Abstract] [Full Text] [Related]

  • 18. Monoclonal antibodies to the CD5 antigen can provide the necessary second signal for activation of isolated resting T cells by solid-phase-bound OKT3.
    Ceuppens JL, Baroja ML.
    J Immunol; 1986 Sep 15; 137(6):1816-21. PubMed ID: 3091691
    [Abstract] [Full Text] [Related]

  • 19. Valency of CD3 binding and internalization of the CD3 cell-surface complex control T cell responses to second signals: distinction between effects on protein kinase C, cytoplasmic free calcium, and proliferation.
    Ledbetter JA, June CH, Martin PJ, Spooner CE, Hansen JA, Meier KE.
    J Immunol; 1986 Jun 01; 136(11):3945-52. PubMed ID: 3084650
    [Abstract] [Full Text] [Related]

  • 20. T cell unresponsiveness to the mitogenic activity of OKT3 antibody results from a deficiency of monocyte Fc gamma receptors for murine IgG2a and inability to cross-link the T3-Ti complex.
    Ceuppens JL, Bloemmen FJ, Van Wauwe JP.
    J Immunol; 1985 Dec 01; 135(6):3882-6. PubMed ID: 2933454
    [Abstract] [Full Text] [Related]

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