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Journal Abstract Search

154 related items for PubMed ID: 15336273

  • 1. Structure-affinity studies for a novel series of homochiral naphtho and tetrahydronaphtho analogues of alpha 1 antagonist WB-4101.
    Bolchi C, Catalano P, Fumagalli L, Gobbi M, Pallavicini M, Pedretti A, Villa L, Vistoli G, Valoti E.
    Bioorg Med Chem; 2004 Sep 15; 12(18):4937-51. PubMed ID: 15336273
    [Abstract] [Full Text] [Related]

  • 2. QSAR study for a novel series of ortho monosubstituted phenoxy analogues of alpha1-adrenoceptor antagonist WB4101.
    Fumagalli L, Bolchi C, Colleoni S, Gobbi M, Moroni B, Pallavicini M, Pedretti A, Villa L, Vistoli G, Valoti E.
    Bioorg Med Chem; 2005 Apr 01; 13(7):2547-59. PubMed ID: 15755656
    [Abstract] [Full Text] [Related]

  • 3. WB4101-related compounds: new, subtype-selective alpha1-adrenoreceptor antagonists (or inverse agonists?).
    Pallavicini M, Budriesi R, Fumagalli L, Ioan P, Chiarini A, Bolchi C, Ugenti MP, Colleoni S, Gobbi M, Valoti E.
    J Med Chem; 2006 Nov 30; 49(24):7140-9. PubMed ID: 17125266
    [Abstract] [Full Text] [Related]

  • 4. Structure-activity relationships in 1,4-benzodioxan-related compounds. 6. Role of the dioxane unit on selectivity for alpha(1)-adrenoreceptor subtypes.
    Quaglia W, Pigini M, Piergentili A, Giannella M, Marucci G, Poggesi E, Leonardi A, Melchiorre C.
    J Med Chem; 1999 Jul 29; 42(15):2961-8. PubMed ID: 10425105
    [Abstract] [Full Text] [Related]

  • 5. Identification of critical extracellular loop residues involved in alpha 1-adrenergic receptor subtype-selective antagonist binding.
    Zhao MM, Hwa J, Perez DM.
    Mol Pharmacol; 1996 Nov 29; 50(5):1118-26. PubMed ID: 8913343
    [Abstract] [Full Text] [Related]

  • 6. Prazosin-related compounds. Effect of transforming the piperazinylquinazoline moiety into an aminomethyltetrahydroacridine system on the affinity for alpha1-adrenoreceptors.
    Rosini M, Antonello A, Cavalli A, Bolognesi ML, Minarini A, Marucci G, Poggesi E, Leonardi A, Melchiorre C.
    J Med Chem; 2003 Nov 06; 46(23):4895-903. PubMed ID: 14584940
    [Abstract] [Full Text] [Related]

  • 7.
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  • 8. Affinity and activity profiling of unichiral 8-substituted 1,4-benzodioxane analogues of WB4101 reveals a potent and selective α1B-adrenoceptor antagonist.
    Fumagalli L, Pallavicini M, Budriesi R, Gobbi M, Straniero V, Zagami M, Chiodini G, Bolchi C, Chiarini A, Micucci M, Valoti E.
    Eur J Med Chem; 2012 Dec 06; 58():184-91. PubMed ID: 23124215
    [Abstract] [Full Text] [Related]

  • 9. New pyrimido[5,4-b]indoles as ligands for alpha(1)-adrenoceptor subtypes.
    Romeo G, Materia L, Manetti F, Cagnotto A, Mennini T, Nicoletti F, Botta M, Russo F, Minneman KP.
    J Med Chem; 2003 Jul 03; 46(14):2877-94. PubMed ID: 12825930
    [Abstract] [Full Text] [Related]

  • 10. WB 4101-related compounds. 2. Role of the ethylene chain separating amine and phenoxy units on the affinity for alpha(1)-adrenoreceptor subtypes and 5-HT(1A) receptors.
    Bolognesi ML, Budriesi R, Cavalli A, Chiarini A, Gotti R, Leonardi A, Minarini A, Poggesi E, Recanatini M, Rosini M, Tumiatti V, Melchiorre C.
    J Med Chem; 1999 Oct 07; 42(20):4214-24. PubMed ID: 10514291
    [Abstract] [Full Text] [Related]

  • 11. Synthesis, absolute configuration, and biological profile of the enantiomers of trans-[2-(2,6-dimethoxyphenoxy)ethyl] [(3-p-tolyl-2,3-dihydro-1,4-benzodioxin-2-yl)methyl]amine (mephendioxan), a potent competitive alpha 1A-adrenoreceptor antagonist.
    Quaglia W, Pigini M, Tayebati SK, Piergentili A, Giannella M, Leonardi A, Taddei C, Melchiorre C.
    J Med Chem; 1996 May 24; 39(11):2253-8. PubMed ID: 8667368
    [Abstract] [Full Text] [Related]

  • 12. 8-NH2-boldine, an antagonist of alpha1A and alpha1B adrenoceptors without affinity for the alpha1D subtype: structural requirements for aporphines at alpha1-adrenoceptor subtypes.
    Ivorra MD, Valiente M, Martínez S, Madrero Y, Noguera MA, Cassels BK, Sobarzo EM, D'Ocon P.
    Planta Med; 2005 Oct 24; 71(10):897-903. PubMed ID: 16254819
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and biological profile of the enantiomers of [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-cis-octahydroquinoxalin- 1-yl]furan-2-ylmethanone (cyclazosin), a potent competitive alpha 1B- adrenoceptor antagonist.
    Giardinà D, Crucianelli M, Romanelli R, Leonardi A, Poggesi E, Melchiorre C.
    J Med Chem; 1996 Nov 08; 39(23):4602-7. PubMed ID: 8917649
    [Abstract] [Full Text] [Related]

  • 14. 1,3-dioxolane-based ligands as a novel class of alpha1-adrenoceptor antagonists.
    Brasili L, Sorbi C, Franchini S, Manicardi M, Angeli P, Marucci G, Leonardi A, Poggesi E.
    J Med Chem; 2003 Apr 10; 46(8):1504-11. PubMed ID: 12672251
    [Abstract] [Full Text] [Related]

  • 15. QSAR study for a novel series of ortho disubstituted phenoxy analogues of alpha1-adrenoceptor antagonist WB4101.
    Pallavicini M, Fumagalli L, Gobbi M, Bolchi C, Colleoni S, Moroni B, Pedretti A, Rusconi C, Vistoli G, Valoti E.
    Eur J Med Chem; 2006 Sep 10; 41(9):1025-40. PubMed ID: 16737760
    [Abstract] [Full Text] [Related]

  • 16. 1,2,4-Benzothiadiazine derivatives as alpha1 and 5-HT1A receptor ligands.
    Tait A, Luppi A, Franchini S, Preziosi E, Parenti C, Buccioni M, Marucci G, Leonardi A, Poggesi E, Brasili L.
    Bioorg Med Chem Lett; 2005 Feb 15; 15(4):1185-8. PubMed ID: 15686938
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and structure-affinity relationship investigations of 5-heteroaryl-substituted analogues of the antipsychotic sertindole. A new class of highly selective alpha(1) adrenoceptor antagonists.
    Balle T, Perregaard J, Ramirez MT, Larsen AK, Søby KK, Liljefors T, Andersen K.
    J Med Chem; 2003 Jan 16; 46(2):265-83. PubMed ID: 12519065
    [Abstract] [Full Text] [Related]

  • 18. Phenylalanine in the second membrane-spanning domain of alpha 1A-adrenergic receptor determines subtype selectivity of dihydropyridine antagonists.
    Hamaguchi N, True TA, Saussy DL, Jeffs PW.
    Biochemistry; 1996 Nov 12; 35(45):14312-7. PubMed ID: 8916917
    [Abstract] [Full Text] [Related]

  • 19. Structure-activity relationships in 1,4-benzodioxan-related compounds. 7. Selectivity of 4-phenylchroman analogues for alpha(1)-adrenoreceptor subtypes.
    Quaglia W, Pigini M, Piergentili A, Giannella M, Gentili F, Marucci G, Carrieri A, Carotti A, Poggesi E, Leonardi A, Melchiorre C.
    J Med Chem; 2002 Apr 11; 45(8):1633-43. PubMed ID: 11931617
    [Abstract] [Full Text] [Related]

  • 20. 1,3-Dioxolane-based ligands as rigid analogues of naftopidil: structure-affinity/activity relationships at alpha1 and 5-HT1A receptors.
    Sorbi C, Franchini S, Tait A, Prandi A, Gallesi R, Angeli P, Marucci G, Pirona L, Poggesi E, Brasili L.
    ChemMedChem; 2009 Mar 11; 4(3):393-9. PubMed ID: 19152363
    [Abstract] [Full Text] [Related]

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