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Journal Abstract Search

269 related items for PubMed ID: 15338962

  • 1. Design and development of BACE-1 inhibitors.
    Cumming JN, Iserloh U, Kennedy ME.
    Curr Opin Drug Discov Devel; 2004 Jul; 7(4):536-56. PubMed ID: 15338962
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  • 2. Progress toward a practical BACE-1 inhibitor.
    Hills ID, Vacca JP.
    Curr Opin Drug Discov Devel; 2007 Jul; 10(4):383-91. PubMed ID: 17659479
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  • 4. Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo.
    Hussain I, Hawkins J, Harrison D, Hille C, Wayne G, Cutler L, Buck T, Walter D, Demont E, Howes C, Naylor A, Jeffrey P, Gonzalez MI, Dingwall C, Michel A, Redshaw S, Davis JB.
    J Neurochem; 2007 Feb; 100(3):802-9. PubMed ID: 17156133
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  • 5. The potential of BACE inhibitors for Alzheimer's therapy.
    Potter H, Dressler D.
    Nat Biotechnol; 2000 Feb; 18(2):125-6. PubMed ID: 10657070
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  • 6. BACE: Therapeutic target and potential biomarker for Alzheimer's disease.
    Evin G, Barakat A, Masters CL.
    Int J Biochem Cell Biol; 2010 Dec; 42(12):1923-6. PubMed ID: 20817005
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  • 11. An inhibitor binding pocket distinct from the catalytic active site on human beta-APP cleaving enzyme.
    Kornacker MG, Lai Z, Witmer M, Ma J, Hendrick J, Lee VG, Riexinger DJ, Mapelli C, Metzler W, Copeland RA.
    Biochemistry; 2005 Aug 30; 44(34):11567-73. PubMed ID: 16114893
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  • 13. Design and synthesis of 1,4-dihydropyridine derivatives as BACE-1 inhibitors.
    Choi SJ, Cho JH, Im I, Lee SD, Jang JY, Oh YM, Jung YK, Jeon ES, Kim YC.
    Eur J Med Chem; 2010 Jun 30; 45(6):2578-90. PubMed ID: 20303626
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  • 17. Calculation of the binding affinity of beta-secretase inhibitors using the linear interaction energy method.
    Tounge BA, Reynolds CH.
    J Med Chem; 2003 May 22; 46(11):2074-82. PubMed ID: 12747779
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  • 18. gamma-Secretase as a target for drug intervention in Alzheimer's disease.
    Harrison T, Churcher I, Beher D.
    Curr Opin Drug Discov Devel; 2004 Sep 22; 7(5):709-19. PubMed ID: 15503873
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  • 19. New hope on Alzheimer's.
    Golden F.
    Time; 1999 Nov 01; 154(18):84. PubMed ID: 10622836
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  • 20. Novel non-peptide beta-secretase inhibitors derived from structure-based virtual screening and bioassay.
    Xu W, Chen G, Liew OW, Zuo Z, Jiang H, Zhu W.
    Bioorg Med Chem Lett; 2009 Jun 15; 19(12):3188-92. PubMed ID: 19447035
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