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Journal Abstract Search


221 related items for PubMed ID: 15339150

  • 1. Crystallographic structures of two bisphosphonate:1-deoxyxylulose-5-phosphate reductoisomerase complexes.
    Yajima S, Hara K, Sanders JM, Yin F, Ohsawa K, Wiesner J, Jomaa H, Oldfield E.
    J Am Chem Soc; 2004 Sep 08; 126(35):10824-5. PubMed ID: 15339150
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  • 2. 1-Deoxy-D-xylulose 5-phosphate reductoisomerase: an overview.
    Proteau PJ.
    Bioorg Chem; 2004 Dec 08; 32(6):483-93. PubMed ID: 15530989
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  • 3. Substrate analogs for the investigation of deoxyxylulose 5-phosphate reductoisomerase inhibition: synthesis and evaluation.
    Phaosiri C, Proteau PJ.
    Bioorg Med Chem Lett; 2004 Nov 01; 14(21):5309-12. PubMed ID: 15454217
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  • 4. Studies addressing the importance of charge in the binding of fosmidomycin-like molecules to deoxyxylulosephosphate reductoisomerase.
    Perruchon J, Ortmann R, Altenkämper M, Silber K, Wiesner J, Jomaa H, Klebe G, Schlitzer M.
    ChemMedChem; 2008 Aug 01; 3(8):1232-41. PubMed ID: 18470849
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  • 12. Towards new antimalarial drugs: synthesis of non-hydrolyzable phosphate mimics as feed for a predictive QSAR study on 1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors.
    Giessmann D, Heidler P, Haemers T, Van Calenbergh S, Reichenberg A, Jomaa H, Weidemeyer C, Sanderbrand S, Wiesner J, Link A.
    Chem Biodivers; 2008 Apr 01; 5(4):643-56. PubMed ID: 18421757
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  • 14. Evaluation of fosmidomycin analogs as inhibitors of the Synechocystis sp. PCC6803 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
    Woo YH, Fernandes RP, Proteau PJ.
    Bioorg Med Chem; 2006 Apr 01; 14(7):2375-85. PubMed ID: 16310360
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  • 15. Structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in a quaternary complex with a magnesium ion, NADPH and the antimalarial drug fosmidomycin.
    Yajima S, Hara K, Iino D, Sasaki Y, Kuzuyama T, Ohsawa K, Seto H.
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2007 Jun 01; 63(Pt 6):466-70. PubMed ID: 17554164
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  • 16. Modifications around the hydroxamic acid chelating group of fosmidomycin, an inhibitor of the metalloenzyme 1-deoxyxylulose 5-phosphate reductoisomerase (DXR).
    Zinglé C, Kuntz L, Tritsch D, Grosdemange-Billiard C, Rohmer M.
    Bioorg Med Chem Lett; 2012 Nov 01; 22(21):6563-7. PubMed ID: 23025997
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  • 17. A high-throughput screening assay for simultaneous selection of inhibitors of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate synthase (Dxs) or 1-deoxy-D-xylulose 5-phosphate reductoisomerase (Dxr).
    Humnabadkar V, Jha RK, Ghatnekar N, De Sousa SM.
    J Biomol Screen; 2011 Mar 01; 16(3):303-12. PubMed ID: 21335601
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  • 18. Novel deoxyxylulosephosphate-reductoisomerase inhibitors: fosmidomycin derivatives with spacious acyl residues.
    Ortmann R, Wiesner J, Silber K, Klebe G, Jomaa H, Schlitzer M.
    Arch Pharm (Weinheim); 2007 Sep 01; 340(9):483-90. PubMed ID: 17806130
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  • 20. High-throughput screen for inhibitors of 1-deoxy-d-xylulose 5-phosphate reductoisomerase by surrogate ligand competition.
    Gottlin EB, Benson RE, Conary S, Antonio B, Duke K, Payne ES, Ashraf SS, Christensen DJ.
    J Biomol Screen; 2003 Jun 01; 8(3):332-9. PubMed ID: 12857387
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