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221 related items for PubMed ID: 15339150
1. Crystallographic structures of two bisphosphonate:1-deoxyxylulose-5-phosphate reductoisomerase complexes. Yajima S, Hara K, Sanders JM, Yin F, Ohsawa K, Wiesner J, Jomaa H, Oldfield E. J Am Chem Soc; 2004 Sep 08; 126(35):10824-5. PubMed ID: 15339150 [Abstract] [Full Text] [Related]
3. Substrate analogs for the investigation of deoxyxylulose 5-phosphate reductoisomerase inhibition: synthesis and evaluation. Phaosiri C, Proteau PJ. Bioorg Med Chem Lett; 2004 Nov 01; 14(21):5309-12. PubMed ID: 15454217 [Abstract] [Full Text] [Related]
4. Studies addressing the importance of charge in the binding of fosmidomycin-like molecules to deoxyxylulosephosphate reductoisomerase. Perruchon J, Ortmann R, Altenkämper M, Silber K, Wiesner J, Jomaa H, Klebe G, Schlitzer M. ChemMedChem; 2008 Aug 01; 3(8):1232-41. PubMed ID: 18470849 [Abstract] [Full Text] [Related]
12. Towards new antimalarial drugs: synthesis of non-hydrolyzable phosphate mimics as feed for a predictive QSAR study on 1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors. Giessmann D, Heidler P, Haemers T, Van Calenbergh S, Reichenberg A, Jomaa H, Weidemeyer C, Sanderbrand S, Wiesner J, Link A. Chem Biodivers; 2008 Apr 01; 5(4):643-56. PubMed ID: 18421757 [Abstract] [Full Text] [Related]
14. Evaluation of fosmidomycin analogs as inhibitors of the Synechocystis sp. PCC6803 1-deoxy-D-xylulose 5-phosphate reductoisomerase. Woo YH, Fernandes RP, Proteau PJ. Bioorg Med Chem; 2006 Apr 01; 14(7):2375-85. PubMed ID: 16310360 [Abstract] [Full Text] [Related]
15. Structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in a quaternary complex with a magnesium ion, NADPH and the antimalarial drug fosmidomycin. Yajima S, Hara K, Iino D, Sasaki Y, Kuzuyama T, Ohsawa K, Seto H. Acta Crystallogr Sect F Struct Biol Cryst Commun; 2007 Jun 01; 63(Pt 6):466-70. PubMed ID: 17554164 [Abstract] [Full Text] [Related]
16. Modifications around the hydroxamic acid chelating group of fosmidomycin, an inhibitor of the metalloenzyme 1-deoxyxylulose 5-phosphate reductoisomerase (DXR). Zinglé C, Kuntz L, Tritsch D, Grosdemange-Billiard C, Rohmer M. Bioorg Med Chem Lett; 2012 Nov 01; 22(21):6563-7. PubMed ID: 23025997 [Abstract] [Full Text] [Related]
17. A high-throughput screening assay for simultaneous selection of inhibitors of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate synthase (Dxs) or 1-deoxy-D-xylulose 5-phosphate reductoisomerase (Dxr). Humnabadkar V, Jha RK, Ghatnekar N, De Sousa SM. J Biomol Screen; 2011 Mar 01; 16(3):303-12. PubMed ID: 21335601 [Abstract] [Full Text] [Related]