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Journal Abstract Search

203 related items for PubMed ID: 15341489

  • 1. Design, synthesis, and biological evaluation of 1,2,3,7-tetrahydro-6h-purin-6-one and 3,7-dihydro-1h-purine-2,6-dione derivatives as corticotropin-releasing factor(1) receptor antagonists.
    Hartz RA, Nanda KK, Ingalls CL, Ahuja VT, Molski TF, Zhang G, Wong H, Peng Y, Kelley M, Lodge NJ, Zaczek R, Gilligan PJ, Trainor GL.
    J Med Chem; 2004 Sep 09; 47(19):4741-54. PubMed ID: 15341489
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  • 6. Design, synthesis, and structure-activity relationships of novel pyrazolo[5,1-b]thiazole derivatives as potent and orally active corticotropin-releasing factor 1 receptor antagonists.
    Takahashi Y, Hashizume M, Shin K, Terauchi T, Takeda K, Hibi S, Murata-Tai K, Fujisawa M, Shikata K, Taguchi R, Ino M, Shibata H, Yonaga M.
    J Med Chem; 2012 Oct 11; 55(19):8450-63. PubMed ID: 22971011
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  • 8. Heteroaryl-substituted 4-(1H-pyrazol-1-yl)-5,6-dihydro-1H-pyrrolo[2,3-d]pyrimidine derivatives as potent and selective corticotropin-releasing factor receptor-1 antagonists.
    Sabbatini FM, Di Fabio R, St-Denis Y, Capelli AM, Castiglioni E, Contini S, Donati D, Fazzolari E, Gentile G, Micheli F, Pavone F, Rinaldi M, Pasquarello A, Zampori MG, Di Felice P, Zarantonello P, Arban R, Perini B, Vitulli G, Benedetti R, Oliosi B, Worby A.
    ChemMedChem; 2008 Feb 11; 3(2):226-9. PubMed ID: 18000940
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  • 9. New pyrrolo[2,1-f]purine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives as potent and selective human A3 adenosine receptor antagonists.
    Baraldi PG, Preti D, Tabrizi MA, Fruttarolo F, Romagnoli R, Zaid NA, Moorman AR, Merighi S, Varani K, Borea PA.
    J Med Chem; 2005 Jul 14; 48(14):4697-701. PubMed ID: 16000006
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  • 14. Synthesis, structure-activity relationships, and in vivo properties of 3,4-dihydro-1H-pyrido[2,3-b]pyrazin-2-ones as corticotropin-releasing factor-1 receptor antagonists.
    Dzierba CD, Takvorian AG, Rafalski M, Kasireddy-Polam P, Wong H, Molski TF, Zhang G, Li YW, Lelas S, Peng Y, McElroy JF, Zaczek RC, Taub RA, Combs AP, Gilligan PJ, Trainor GL.
    J Med Chem; 2004 Nov 04; 47(23):5783-90. PubMed ID: 15509177
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  • 15. The design, synthesis and structure-activity relationships of 1-aryl-4-aminoalkylisoquinolines: a novel series of CRF-1 receptor antagonists.
    Yoon T, De Lombaert S, Brodbeck R, Gulianello M, Chandrasekhar J, Horvath RF, Ge P, Kershaw MT, Krause JE, Kehne J, Hoffman D, Doller D, Hodgetts KJ.
    Bioorg Med Chem Lett; 2008 Feb 01; 18(3):891-6. PubMed ID: 18180159
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  • 17. Design, synthesis, and SAR of 2-dialkylamino-4-arylpyrimidines as potent and selective corticotropin-releasing factor(1) (CRF(1)) receptor antagonists.
    Huang CQ, Grigoriadis DE, Liu Z, McCarthy JR, Ramphal J, Webb T, Whitten JP, Xie MY, Chen C.
    Bioorg Med Chem Lett; 2004 May 03; 14(9):2083-6. PubMed ID: 15080983
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  • 20. Chemical modification of aryl-1,2,3,6-tetrahydropyridinopyrimidine derivative to discover corticotropin-releasing factor(1) receptor antagonists: aryl-1,2,3,6-tetrahydropyridino-purine, -3H-1,2,3-triazolo[4,5-d)pyrimidine, -purin-8-one, and -7H-pyrrolo[2,3-d]pyrimidine derivatives.
    Kumagai T, Okubo T, Kataoka-Okubo H, Chaki S, Okuyama S, Nakazato A.
    Bioorg Med Chem; 2001 May 03; 9(5):1357-63. PubMed ID: 11377193
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