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Journal Abstract Search


180 related items for PubMed ID: 15350132

  • 1. The mechanism of target base attack in DNA cytosine carbon 5 methylation.
    Svedruzić ZM, Reich NO.
    Biochemistry; 2004 Sep 14; 43(36):11460-73. PubMed ID: 15350132
    [Abstract] [Full Text] [Related]

  • 2. DNA cytosine C5 methyltransferase Dnmt1: catalysis-dependent release of allosteric inhibition.
    Svedruzić ZM, Reich NO.
    Biochemistry; 2005 Jul 12; 44(27):9472-85. PubMed ID: 15996102
    [Abstract] [Full Text] [Related]

  • 3. S-adenosyl-L-methionine-dependent methyl transfer: observable precatalytic intermediates during DNA cytosine methylation.
    Youngblood B, Shieh FK, Buller F, Bullock T, Reich NO.
    Biochemistry; 2007 Jul 31; 46(30):8766-75. PubMed ID: 17616174
    [Abstract] [Full Text] [Related]

  • 4. The role of Arg165 towards base flipping, base stabilization and catalysis in M.HhaI.
    Shieh FK, Youngblood B, Reich NO.
    J Mol Biol; 2006 Sep 22; 362(3):516-27. PubMed ID: 16926025
    [Abstract] [Full Text] [Related]

  • 5. Active site dynamics of the HhaI methyltransferase: insights from computer simulation.
    Lau EY, Bruice TC.
    J Mol Biol; 1999 Oct 15; 293(1):9-18. PubMed ID: 10512711
    [Abstract] [Full Text] [Related]

  • 6. Mechanism of inhibition of DNA (cytosine C5)-methyltransferases by oligodeoxyribonucleotides containing 5,6-dihydro-5-azacytosine.
    Sheikhnejad G, Brank A, Christman JK, Goddard A, Alvarez E, Ford H, Marquez VE, Marasco CJ, Sufrin JR, O'gara M, Cheng X.
    J Mol Biol; 1999 Feb 05; 285(5):2021-34. PubMed ID: 9925782
    [Abstract] [Full Text] [Related]

  • 7. AdoMet-dependent methyl-transfer: Glu119 is essential for DNA C5-cytosine methyltransferase M.HhaI.
    Shieh FK, Reich NO.
    J Mol Biol; 2007 Nov 09; 373(5):1157-68. PubMed ID: 17897676
    [Abstract] [Full Text] [Related]

  • 8. Probing a rate-limiting step by mutational perturbation of AdoMet binding in the HhaI methyltransferase.
    Merkiene E, Klimasauskas S.
    Nucleic Acids Res; 2005 Nov 09; 33(1):307-15. PubMed ID: 15653631
    [Abstract] [Full Text] [Related]

  • 9. Murine DNA (cytosine-5-)-methyltransferase: steady-state and substrate trapping analyses of the kinetic mechanism.
    Flynn J, Reich N.
    Biochemistry; 1998 Oct 27; 37(43):15162-9. PubMed ID: 9790680
    [Abstract] [Full Text] [Related]

  • 10. Determinants of sequence-specific DNA methylation: target recognition and catalysis are coupled in M.HhaI.
    Youngblood B, Buller F, Reich NO.
    Biochemistry; 2006 Dec 26; 45(51):15563-72. PubMed ID: 17176077
    [Abstract] [Full Text] [Related]

  • 11. Engineered extrahelical base destabilization enhances sequence discrimination of DNA methyltransferase M.HhaI.
    Youngblood B, Shieh FK, De Los Rios S, Perona JJ, Reich NO.
    J Mol Biol; 2006 Sep 15; 362(2):334-46. PubMed ID: 16919299
    [Abstract] [Full Text] [Related]

  • 12. HhaI DNA methyltransferase uses the protruding Gln237 for active flipping of its target cytosine.
    Daujotyte D, Serva S, Vilkaitis G, Merkiene E, Venclovas C, Klimasauskas S.
    Structure; 2004 Jun 15; 12(6):1047-55. PubMed ID: 15274924
    [Abstract] [Full Text] [Related]

  • 13. Functional roles of the conserved aromatic amino acid residues at position 108 (motif IV) and position 196 (motif VIII) in base flipping and catalysis by the N6-adenine DNA methyltransferase from Thermus aquaticus.
    Pues H, Bleimling N, Holz B, Wölcke J, Weinhold E.
    Biochemistry; 1999 Feb 02; 38(5):1426-34. PubMed ID: 9931007
    [Abstract] [Full Text] [Related]

  • 14. The recognition pathway for the DNA cytosine methyltransferase M.HhaI.
    Zhou H, Purdy MM, Dahlquist FW, Reich NO.
    Biochemistry; 2009 Aug 25; 48(33):7807-16. PubMed ID: 19580326
    [Abstract] [Full Text] [Related]

  • 15. Murine DNA cytosine-C5 methyltransferase: pre-steady- and steady-state kinetic analysis with regulatory DNA sequences.
    Flynn J, Glickman JF, Reich NO.
    Biochemistry; 1996 Jun 11; 35(23):7308-15. PubMed ID: 8652507
    [Abstract] [Full Text] [Related]

  • 16. Kinetic and catalytic mechanism of HhaI methyltransferase.
    Wu JC, Santi DV.
    J Biol Chem; 1987 Apr 05; 262(10):4778-86. PubMed ID: 3558369
    [Abstract] [Full Text] [Related]

  • 17. Long-range structural and dynamical changes induced by cofactor binding in DNA methyltransferase M.HhaI.
    Zhou H, Shatz W, Purdy MM, Fera N, Dahlquist FW, Reich NO.
    Biochemistry; 2007 Jun 19; 46(24):7261-8. PubMed ID: 17523600
    [Abstract] [Full Text] [Related]

  • 18. Structure of the N6-adenine DNA methyltransferase M.TaqI in complex with DNA and a cofactor analog.
    Goedecke K, Pignot M, Goody RS, Scheidig AJ, Weinhold E.
    Nat Struct Biol; 2001 Feb 19; 8(2):121-5. PubMed ID: 11175899
    [Abstract] [Full Text] [Related]

  • 19. Impact of benzo[a]pyrene-2'-deoxyguanosine lesions on methylation of DNA by SssI and HhaI DNA methyltransferases.
    Subach OM, Baskunov VB, Darii MV, Maltseva DV, Alexandrov DA, Kirsanova OV, Kolbanovskiy A, Kolbanovskiy M, Johnson F, Bonala R, Geacintov NE, Gromova ES.
    Biochemistry; 2006 May 16; 45(19):6142-59. PubMed ID: 16681387
    [Abstract] [Full Text] [Related]

  • 20. The coupling of tight DNA binding and base flipping: identification of a conserved structural motif in base flipping enzymes.
    Estabrook RA, Lipson R, Hopkins B, Reich N.
    J Biol Chem; 2004 Jul 23; 279(30):31419-28. PubMed ID: 15143064
    [Abstract] [Full Text] [Related]


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