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Journal Abstract Search


135 related items for PubMed ID: 15356922

  • 1. Metabolism of chlorambucil by rat liver microsomal glutathione S-transferase.
    Zhang J, Ye Z, Lou Y.
    Chem Biol Interact; 2004 Aug 10; 149(1):61-7. PubMed ID: 15356922
    [Abstract] [Full Text] [Related]

  • 2. Relationship between activation of microsomal glutathione S-transferase and metabolism behavior of chlorambucil.
    Zhang J, Lou YJ.
    Pharmacol Res; 2003 Dec 10; 48(6):623-30. PubMed ID: 14527828
    [Abstract] [Full Text] [Related]

  • 3. Chlorambucil-monoglutathionyl conjugate is sequestered by human alpha class glutathione S-transferases.
    Meyer DJ, Gilmore KS, Harris JM, Hartley JA, Ketterer B.
    Br J Cancer; 1992 Sep 10; 66(3):433-8. PubMed ID: 1520581
    [Abstract] [Full Text] [Related]

  • 4. Metabolism of melphalan by rat liver microsomal glutathione S-transferase.
    Zhang J, Ye Z, Lou Y.
    Chem Biol Interact; 2005 Apr 15; 152(2-3):101-6. PubMed ID: 15840383
    [Abstract] [Full Text] [Related]

  • 5. Role of multidrug resistance protein 1 (MRP1) and glutathione S-transferase A1-1 in alkylating agent resistance. Kinetics of glutathione conjugate formation and efflux govern differential cellular sensitivity to chlorambucil versus melphalan toxicity.
    Paumi CM, Ledford BG, Smitherman PK, Townsend AJ, Morrow CS.
    J Biol Chem; 2001 Mar 16; 276(11):7952-6. PubMed ID: 11115505
    [Abstract] [Full Text] [Related]

  • 6. [Rat microsomal glutathione S-transferase 1 alters cytotoxic effects of chlorambucil on PC-3, K562, HepG2 and P388D1 cell lines].
    Chen Z, Ye ZQ, Shi Q.
    Zhejiang Da Xue Xue Bao Yi Xue Ban; 2007 May 16; 36(3):236-40. PubMed ID: 17571305
    [Abstract] [Full Text] [Related]

  • 7. Characterization of a chlorambucil-resistant human ovarian carcinoma cell line overexpressing glutathione S-transferase mu.
    Horton JK, Roy G, Piper JT, Van Houten B, Awasthi YC, Mitra S, Alaoui-Jamali MA, Boldogh I, Singhal SS.
    Biochem Pharmacol; 1999 Aug 15; 58(4):693-702. PubMed ID: 10413308
    [Abstract] [Full Text] [Related]

  • 8. Activity of allelic variants of Pi class human glutathione S-transferase toward chlorambucil.
    Pandya U, Srivastava SK, Singhal SS, Pal A, Awasthi S, Zimniak P, Awasthi YC, Singh SV.
    Biochem Biophys Res Commun; 2000 Nov 11; 278(1):258-62. PubMed ID: 11071881
    [Abstract] [Full Text] [Related]

  • 9. Role of multidrug resistance protein 2 (MRP2, ABCC2) in alkylating agent detoxification: MRP2 potentiates glutathione S-transferase A1-1-mediated resistance to chlorambucil cytotoxicity.
    Smitherman PK, Townsend AJ, Kute TE, Morrow CS.
    J Pharmacol Exp Ther; 2004 Jan 11; 308(1):260-7. PubMed ID: 14569069
    [Abstract] [Full Text] [Related]

  • 10. Conjugation of chlorambucil with GSH by GST purified from human colon adenocarcinoma cells and its inhibition by plant polyphenols.
    Zhang K, Wong KP, Chow P.
    Life Sci; 2003 Apr 25; 72(23):2629-40. PubMed ID: 12672508
    [Abstract] [Full Text] [Related]

  • 11. Characterization of glutathione conjugates of chlorambucil by fast atom bombardment and thermospray liquid chromatography/mass spectrometry.
    Dulik DM, Colvin OM, Fenselau C.
    Biomed Environ Mass Spectrom; 1990 Apr 25; 19(4):248-52. PubMed ID: 2340362
    [Abstract] [Full Text] [Related]

  • 12. Glutathione conjugation of the cytostatic drug ifosfamide and the role of human glutathione S-transferases.
    Dirven HA, Megens L, Oudshoorn MJ, Dingemanse MA, van Ommen B, van Bladeren PJ.
    Chem Res Toxicol; 1995 Apr 25; 8(7):979-86. PubMed ID: 8555414
    [Abstract] [Full Text] [Related]

  • 13. The role of human glutathione S-transferase isoenzymes in the formation of glutathione conjugates of the alkylating cytostatic drug thiotepa.
    Dirven HA, Dictus EL, Broeders NL, van Ommen B, van Bladeren PJ.
    Cancer Res; 1995 Apr 15; 55(8):1701-6. PubMed ID: 7712478
    [Abstract] [Full Text] [Related]

  • 14. Increase in liver microsomal glutathione S-transferase activity by phenobarbital treatment of rats. Possible involvement of oxidative activation via cytochrome P450.
    Aniya Y, Shimoji M, Naito A.
    Biochem Pharmacol; 1993 Nov 17; 46(10):1741-7. PubMed ID: 8250959
    [Abstract] [Full Text] [Related]

  • 15. Identification of a glutathione S-transferase associated with microsomes of tumor cells resistant to nitrogen mustards.
    Clapper ML, Tew KD.
    Biochem Pharmacol; 1989 Jun 15; 38(12):1915-21. PubMed ID: 2742599
    [Abstract] [Full Text] [Related]

  • 16. The spontaneous and glutathione S-transferase-mediated reaction of chlorambucil with glutathione.
    Ciaccio PJ, Tew KD, LaCreta FP.
    Cancer Commun; 1990 Jun 15; 2(8):279-85. PubMed ID: 2390420
    [Abstract] [Full Text] [Related]

  • 17. Microsomal glutathione S-transferase A1-1 with glutathione peroxidase activity from sheep liver: molecular cloning, expression and characterization.
    Prabhu KS, Reddy PV, Gumpricht E, Hildenbrandt GR, Scholz RW, Sordillo LM, Reddy CC.
    Biochem J; 2001 Dec 01; 360(Pt 2):345-54. PubMed ID: 11716762
    [Abstract] [Full Text] [Related]

  • 18. Denitrosation of the anti-cancer drug 1,3-bis(2-chloroethyl)-1-nitrosourea catalyzed by microsomal glutathione S-transferase and cytochrome P450 monooxygenases.
    Weber GF, Waxman DJ.
    Arch Biochem Biophys; 1993 Dec 01; 307(2):369-78. PubMed ID: 8274024
    [Abstract] [Full Text] [Related]

  • 19. In vitro metabolism of cyanohydroxybutene: formation of a glutathione-S-transferase catalyzed product.
    Davis MA, Wallig MA, Jeffery EH.
    Res Commun Chem Pathol Pharmacol; 1993 Mar 01; 79(3):343-53. PubMed ID: 8480079
    [Abstract] [Full Text] [Related]

  • 20. Differential catalytic efficiency of allelic variants of human glutathione S-transferase Pi in catalyzing the glutathione conjugation of thiotepa.
    Srivastava SK, Singhal SS, Hu X, Awasthi YC, Zimniak P, Singh SV.
    Arch Biochem Biophys; 1999 Jun 01; 366(1):89-94. PubMed ID: 10334868
    [Abstract] [Full Text] [Related]


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