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77 related items for PubMed ID: 15358112

  • 1. The bortezomib-induced mitochondrial damage is mediated by accumulation of active protein kinase C-delta.
    Durrant D, Liu J, Yang HS, Lee RM.
    Biochem Biophys Res Commun; 2004 Sep 03; 321(4):905-8. PubMed ID: 15358112
    [Abstract] [Full Text] [Related]

  • 2. Induction of apoptosis by Se-MSC in U937 human leukemia cells through release of cytochrome c and activation of caspases and PKC-delta: mutual regulation between caspases and PKC-delta via a positive feedback mechanism.
    Jang BC, Choi ES, Im KJ, Baek WK, Kwon TK, Suh MH, Kim SP, Park JW, Suh SI.
    Int J Mol Med; 2003 Nov 03; 12(5):733-9. PubMed ID: 14533002
    [Abstract] [Full Text] [Related]

  • 3. Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitors.
    Pei XY, Dai Y, Grant S.
    Clin Cancer Res; 2004 Jun 01; 10(11):3839-52. PubMed ID: 15173093
    [Abstract] [Full Text] [Related]

  • 4. Effects of the proteasome inhibitor, bortezomib, on apoptosis in isolated lymphocytes obtained from patients with chronic lymphocytic leukemia.
    Pahler JC, Ruiz S, Niemer I, Calvert LR, Andreeff M, Keating M, Faderl S, McConkey DJ.
    Clin Cancer Res; 2003 Oct 01; 9(12):4570-7. PubMed ID: 14555532
    [Abstract] [Full Text] [Related]

  • 5. Rottlerin sensitizes colon carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via uncoupling of the mitochondria independent of protein kinase C.
    Tillman DM, Izeradjene K, Szucs KS, Douglas L, Houghton JA.
    Cancer Res; 2003 Aug 15; 63(16):5118-25. PubMed ID: 12941843
    [Abstract] [Full Text] [Related]

  • 6. Down-regulation of caspase-2 by rottlerin via protein kinase C-delta-independent pathway.
    Basu A, Adkins B, Basu C.
    Cancer Res; 2008 Apr 15; 68(8):2795-802. PubMed ID: 18413747
    [Abstract] [Full Text] [Related]

  • 7. JNK and AP-1 mediate apoptosis induced by bortezomib in HepG2 cells via FasL/caspase-8 and mitochondria-dependent pathways.
    Lauricella M, Emanuele S, D'Anneo A, Calvaruso G, Vassallo B, Carlisi D, Portanova P, Vento R, Tesoriere G.
    Apoptosis; 2006 Apr 15; 11(4):607-25. PubMed ID: 16528474
    [Abstract] [Full Text] [Related]

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  • 9. The PKC delta inhibitor, rottlerin, induces apoptosis of haematopoietic cell lines through mitochondrial membrane depolarization and caspases' cascade.
    Liao YF, Hung YC, Chang WH, Tsay GJ, Hour TC, Hung HC, Liu GY.
    Life Sci; 2005 Jun 24; 77(6):707-19. PubMed ID: 15922001
    [Abstract] [Full Text] [Related]

  • 10. PKC-delta is an apoptotic lamin kinase.
    Cross T, Griffiths G, Deacon E, Sallis R, Gough M, Watters D, Lord JM.
    Oncogene; 2000 May 04; 19(19):2331-7. PubMed ID: 10822384
    [Abstract] [Full Text] [Related]

  • 11. A pivotal role for Mcl-1 in Bortezomib-induced apoptosis.
    Podar K, Gouill SL, Zhang J, Opferman JT, Zorn E, Tai YT, Hideshima T, Amiot M, Chauhan D, Harousseau JL, Anderson KC.
    Oncogene; 2008 Jan 31; 27(6):721-31. PubMed ID: 17653083
    [Abstract] [Full Text] [Related]

  • 12. Arsenic trioxide and proteasome inhibitor bortezomib synergistically induce apoptosis in leukemic cells: the role of protein kinase Cdelta.
    Yan H, Wang YC, Li D, Wang Y, Liu W, Wu YL, Chen GQ.
    Leukemia; 2007 Jul 31; 21(7):1488-95. PubMed ID: 17495969
    [Abstract] [Full Text] [Related]

  • 13. The proteasome inhibitor bortezomib induces apoptosis in human retinoblastoma cell lines in vitro.
    Poulaki V, Mitsiades CS, Kotoula V, Negri J, McMillin D, Miller JW, Mitsiades N.
    Invest Ophthalmol Vis Sci; 2007 Oct 31; 48(10):4706-19. PubMed ID: 17898295
    [Abstract] [Full Text] [Related]

  • 14. Tetrandrine-induced apoptosis is mediated by activation of caspases and PKC-delta in U937 cells.
    Jang BC, Lim KJ, Paik JH, Cho JW, Baek WK, Suh MH, Park JB, Kwon TK, Park JW, Kim SP, Shin DH, Song DK, Bae JH, Mun KC, Suh SI.
    Biochem Pharmacol; 2004 May 15; 67(10):1819-29. PubMed ID: 15130759
    [Abstract] [Full Text] [Related]

  • 15. Bortezomib (Velcade) induces p27Kip1 expression through S-phase kinase protein 2 degradation in colorectal cancer.
    Uddin S, Ahmed M, Bavi P, El-Sayed R, Al-Sanea N, AbdulJabbar A, Ashari LH, Alhomoud S, Al-Dayel F, Hussain AR, Al-Kuraya KS.
    Cancer Res; 2008 May 01; 68(9):3379-88. PubMed ID: 18451165
    [Abstract] [Full Text] [Related]

  • 16. Histone deacetylase inhibitor depsipeptide (FK228) induces apoptosis in leukemic cells by facilitating mitochondrial translocation of Bax, which is enhanced by the proteasome inhibitor bortezomib.
    Sutheesophon K, Kobayashi Y, Takatoku MA, Ozawa K, Kano Y, Ishii H, Furukawa Y.
    Acta Haematol; 2006 May 01; 115(1-2):78-90. PubMed ID: 16424655
    [Abstract] [Full Text] [Related]

  • 17. Rottlerin induces apoptosis of HT29 colon carcinoma cells through NAG-1 upregulation via an ERK and p38 MAPK-dependent and PKC δ-independent mechanism.
    Lim JH, Woo SM, Min KJ, Park EJ, Jang JH, Seo BR, Iqbal T, Lee TJ, Kim SH, Choi YH, Kwon TK.
    Chem Biol Interact; 2012 Apr 15; 197(1):1-7. PubMed ID: 22410117
    [Abstract] [Full Text] [Related]

  • 18. Bortezomib primes glioblastoma, including glioblastoma stem cells, for TRAIL by increasing tBid stability and mitochondrial apoptosis.
    Unterkircher T, Cristofanon S, Vellanki SH, Nonnenmacher L, Karpel-Massler G, Wirtz CR, Debatin KM, Fulda S.
    Clin Cancer Res; 2011 Jun 15; 17(12):4019-30. PubMed ID: 21525171
    [Abstract] [Full Text] [Related]

  • 19. The effect of the proteasome inhibitor bortezomib on acute myeloid leukemia cells and drug resistance associated with the CD34+ immature phenotype.
    Colado E, Alvarez-Fernández S, Maiso P, Martín-Sánchez J, Vidriales MB, Garayoa M, Ocio EM, Montero JC, Pandiella A, San Miguel JF.
    Haematologica; 2008 Jan 15; 93(1):57-66. PubMed ID: 18166786
    [Abstract] [Full Text] [Related]

  • 20. A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib.
    Chauhan D, Catley L, Li G, Podar K, Hideshima T, Velankar M, Mitsiades C, Mitsiades N, Yasui H, Letai A, Ovaa H, Berkers C, Nicholson B, Chao TH, Neuteboom ST, Richardson P, Palladino MA, Anderson KC.
    Cancer Cell; 2005 Nov 15; 8(5):407-19. PubMed ID: 16286248
    [Abstract] [Full Text] [Related]

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