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250 related items for PubMed ID: 15364919

  • 1. Protein kinase C Theta inhibits insulin signaling by phosphorylating IRS1 at Ser(1101).
    Li Y, Soos TJ, Li X, Wu J, Degennaro M, Sun X, Littman DR, Birnbaum MJ, Polakiewicz RD.
    J Biol Chem; 2004 Oct 29; 279(44):45304-7. PubMed ID: 15364919
    [Abstract] [Full Text] [Related]

  • 2. Leptin down-regulates insulin action through phosphorylation of serine-318 in insulin receptor substrate 1.
    Hennige AM, Stefan N, Kapp K, Lehmann R, Weigert C, Beck A, Moeschel K, Mushack J, Schleicher E, Häring HU.
    FASEB J; 2006 Jun 29; 20(8):1206-8. PubMed ID: 16611834
    [Abstract] [Full Text] [Related]

  • 3. Akt mediates insulin-stimulated phosphorylation of Ndrg2: evidence for cross-talk with protein kinase C theta.
    Burchfield JG, Lennard AJ, Narasimhan S, Hughes WE, Wasinger VC, Corthals GL, Okuda T, Kondoh H, Biden TJ, Schmitz-Peiffer C.
    J Biol Chem; 2004 Apr 30; 279(18):18623-32. PubMed ID: 14985363
    [Abstract] [Full Text] [Related]

  • 4. Hypochlorous acid via peroxynitrite activates protein kinase Cθ and insulin resistance in adipocytes.
    Zhou J, Wang Q, Ding Y, Zou MH.
    J Mol Endocrinol; 2015 Feb 30; 54(1):25-37. PubMed ID: 25381390
    [Abstract] [Full Text] [Related]

  • 5. Serine 302 Phosphorylation of Mouse Insulin Receptor Substrate 1 (IRS1) Is Dispensable for Normal Insulin Signaling and Feedback Regulation by Hepatic S6 Kinase.
    Copps KD, Hançer NJ, Qiu W, White MF.
    J Biol Chem; 2016 Apr 15; 291(16):8602-17. PubMed ID: 26846849
    [Abstract] [Full Text] [Related]

  • 6. Phosphorylation of Irs1 at SER-522 inhibits insulin signaling.
    Giraud J, Haas M, Feener EP, Copps KD, Dong X, Dunn SL, White MF.
    Mol Endocrinol; 2007 Sep 15; 21(9):2294-302. PubMed ID: 17579213
    [Abstract] [Full Text] [Related]

  • 7. Salicylic acid reverses phorbol 12-myristate-13-acetate (PMA)- and tumor necrosis factor alpha (TNFalpha)-induced insulin receptor substrate 1 (IRS1) serine 307 phosphorylation and insulin resistance in human embryonic kidney 293 (HEK293) cells.
    Jiang G, Dallas-Yang Q, Liu F, Moller DE, Zhang BB.
    J Biol Chem; 2003 Jan 03; 278(1):180-6. PubMed ID: 12409308
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of insulin sensitivity by free fatty acids requires activation of multiple serine kinases in 3T3-L1 adipocytes.
    Gao Z, Zhang X, Zuberi A, Hwang D, Quon MJ, Lefevre M, Ye J.
    Mol Endocrinol; 2004 Aug 03; 18(8):2024-34. PubMed ID: 15143153
    [Abstract] [Full Text] [Related]

  • 9. Regulation of insulin receptor substrate 1 pleckstrin homology domain by protein kinase C: role of serine 24 phosphorylation.
    Nawaratne R, Gray A, Jørgensen CH, Downes CP, Siddle K, Sethi JK.
    Mol Endocrinol; 2006 Aug 03; 20(8):1838-52. PubMed ID: 16574739
    [Abstract] [Full Text] [Related]

  • 10. c-Jun N-terminal kinase (JNK) mediates feedback inhibition of the insulin signaling cascade.
    Lee YH, Giraud J, Davis RJ, White MF.
    J Biol Chem; 2003 Jan 31; 278(5):2896-902. PubMed ID: 12417588
    [Abstract] [Full Text] [Related]

  • 11. Protein kinase C isoforms alpha, delta and theta require insulin receptor substrate-1 to inhibit the tyrosine kinase activity of the insulin receptor in human kidney embryonic cells (HEK 293 cells).
    Kellerer M, Mushack J, Seffer E, Mischak H, Ullrich A, Häring HU.
    Diabetologia; 1998 Jul 31; 41(7):833-8. PubMed ID: 9686926
    [Abstract] [Full Text] [Related]

  • 12. Positive and negative regulation of insulin signaling through IRS-1 phosphorylation.
    Gual P, Le Marchand-Brustel Y, Tanti JF.
    Biochimie; 2005 Jan 31; 87(1):99-109. PubMed ID: 15733744
    [Abstract] [Full Text] [Related]

  • 13. In vitro phosphorylation of insulin receptor substrate 1 by protein kinase C-zeta: functional analysis and identification of novel phosphorylation sites.
    Sommerfeld MR, Metzger S, Stosik M, Tennagels N, Eckel J.
    Biochemistry; 2004 May 18; 43(19):5888-901. PubMed ID: 15134463
    [Abstract] [Full Text] [Related]

  • 14. Insulin-stimulated protein kinase C lambda/zeta activity is reduced in skeletal muscle of humans with obesity and type 2 diabetes: reversal with weight reduction.
    Kim YB, Kotani K, Ciaraldi TP, Henry RR, Kahn BB.
    Diabetes; 2003 Aug 18; 52(8):1935-42. PubMed ID: 12882908
    [Abstract] [Full Text] [Related]

  • 15. Interleukin-1alpha inhibits insulin signaling with phosphorylating insulin receptor substrate-1 on serine residues in 3T3-L1 adipocytes.
    He J, Usui I, Ishizuka K, Kanatani Y, Hiratani K, Iwata M, Bukhari A, Haruta T, Sasaoka T, Kobayashi M.
    Mol Endocrinol; 2006 Jan 18; 20(1):114-24. PubMed ID: 16150868
    [Abstract] [Full Text] [Related]

  • 16. Rosiglitazone, an agonist of peroxisome-proliferator-activated receptor gamma (PPARgamma), decreases inhibitory serine phosphorylation of IRS1 in vitro and in vivo.
    Jiang G, Dallas-Yang Q, Biswas S, Li Z, Zhang BB.
    Biochem J; 2004 Jan 15; 377(Pt 2):339-46. PubMed ID: 14556646
    [Abstract] [Full Text] [Related]

  • 17. Carrageenan Inhibits Insulin Signaling through GRB10-mediated Decrease in Tyr(P)-IRS1 and through Inflammation-induced Increase in Ser(P)307-IRS1.
    Bhattacharyya S, Feferman L, Tobacman JK.
    J Biol Chem; 2015 Apr 24; 290(17):10764-74. PubMed ID: 25784556
    [Abstract] [Full Text] [Related]

  • 18. Activation of protein kinase C alpha inhibits insulin-stimulated tyrosine phosphorylation of insulin receptor substrate-1.
    Chin JE, Liu F, Roth RA.
    Mol Endocrinol; 1994 Jan 24; 8(1):51-8. PubMed ID: 7512195
    [Abstract] [Full Text] [Related]

  • 19. Modulation of human insulin receptor substrate-1 tyrosine phosphorylation by protein kinase Cdelta.
    Greene MW, Morrice N, Garofalo RS, Roth RA.
    Biochem J; 2004 Feb 15; 378(Pt 1):105-16. PubMed ID: 14583092
    [Abstract] [Full Text] [Related]

  • 20. Shp2 is required for protein kinase C-dependent phosphorylation of serine 307 in insulin receptor substrate-1.
    Müssig K, Staiger H, Fiedler H, Moeschel K, Beck A, Kellerer M, Häring HU.
    J Biol Chem; 2005 Sep 23; 280(38):32693-9. PubMed ID: 16055440
    [Abstract] [Full Text] [Related]

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