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300 related items for PubMed ID: 15368366

  • 1. Mutation of the highly conserved Arg165 and Glu168 residues of human Gsalpha disrupts the alphaD-alphaE loop and enhances basal GDP/GTP exchange rate.
    Hinrichs MV, Montecino M, Bunster M, Olate J.
    J Cell Biochem; 2004 Oct 01; 93(2):409-17. PubMed ID: 15368366
    [Abstract] [Full Text] [Related]

  • 2. S111N mutation in the helical domain of human Gs(alpha) reduces its GDP/GTP exchange rate.
    Brito M, Guzmán L, Romo X, Soto X, Hinrichs MV, Olate J.
    J Cell Biochem; 2002 Oct 01; 85(3):615-20. PubMed ID: 11968001
    [Abstract] [Full Text] [Related]

  • 3. Mutagenesis in the switch IV of the helical domain of the human Gsalpha reduces its GDP/GTP exchange rate.
    Echeverría V, Hinrichs MV, Torrejón M, Ropero S, Martinez J, Toro MJ, Olate J.
    J Cell Biochem; 2000 Jan 01; 76(3):368-75. PubMed ID: 10649434
    [Abstract] [Full Text] [Related]

  • 4. What is the role of the helical domain of Gsalpha in the GTPase reaction?
    Shnerb T, Lin N, Shurki A.
    Biochemistry; 2007 Sep 25; 46(38):10875-85. PubMed ID: 17727271
    [Abstract] [Full Text] [Related]

  • 5. Guanine nucleotide exchange-independent activation of Gs protein by beta2-adrenoceptor.
    Ugur O, Oner SS, Molinari P, Ambrosio C, Sayar K, Onaran HO.
    Mol Pharmacol; 2005 Sep 25; 68(3):720-8. PubMed ID: 15933218
    [Abstract] [Full Text] [Related]

  • 6. Activating mutations in the NH2- and COOH-terminal moieties of the Gs alpha subunit have dominant phenotypes and distinguishable kinetics of adenylyl cyclase stimulation.
    Gupta SK, Dhanasekaran N, Heasley LE, Johnson GL.
    J Cell Biochem; 1991 Dec 25; 47(4):359-68. PubMed ID: 1665495
    [Abstract] [Full Text] [Related]

  • 7. Mutagenesis of the conserved residue Glu259 of Gsalpha demonstrates the importance of interactions between switches 2 and 3 for activation.
    Warner DR, Romanowski R, Yu S, Weinstein LS.
    J Biol Chem; 1999 Feb 19; 274(8):4977-84. PubMed ID: 9988742
    [Abstract] [Full Text] [Related]

  • 8. An aspartate residue at the extracellular boundary of TMII and an arginine residue in TMVII of the gastrin-releasing peptide receptor interact to facilitate heterotrimeric G protein coupling.
    Donohue PJ, Sainz E, Akeson M, Kroog GS, Mantey SA, Battey JF, Jensen RT, Northup JK.
    Biochemistry; 1999 Jul 20; 38(29):9366-72. PubMed ID: 10413511
    [Abstract] [Full Text] [Related]

  • 9. Characterisation of the nucleotide exchange factor ITSN1L: evidence for a kinetic discrimination of GEF-stimulated nucleotide release from Cdc42.
    Kintscher C, Groemping Y.
    J Mol Biol; 2009 Mar 27; 387(2):270-83. PubMed ID: 19356586
    [Abstract] [Full Text] [Related]

  • 10. Co-operation of Gsalpha and Gbetagamma in maintaining G2 arrest in Xenopus oocytes.
    Sheng Y, Montplaisir V, Liu XJ.
    J Cell Physiol; 2005 Jan 27; 202(1):32-40. PubMed ID: 15389551
    [Abstract] [Full Text] [Related]

  • 11. Structural evidence for a sequential release mechanism for activation of heterotrimeric G proteins.
    Kapoor N, Menon ST, Chauhan R, Sachdev P, Sakmar TP.
    J Mol Biol; 2009 Nov 06; 393(4):882-97. PubMed ID: 19703466
    [Abstract] [Full Text] [Related]

  • 12. Conditional activation defect of a human Gsalpha mutant.
    Iiri T, Farfel Z, Bourne HR.
    Proc Natl Acad Sci U S A; 1997 May 27; 94(11):5656-61. PubMed ID: 9159128
    [Abstract] [Full Text] [Related]

  • 13. Structural and biochemical characterization of the GTPgammaS-, GDP.Pi-, and GDP-bound forms of a GTPase-deficient Gly42 --> Val mutant of Gialpha1.
    Raw AS, Coleman DE, Gilman AG, Sprang SR.
    Biochemistry; 1997 Dec 16; 36(50):15660-9. PubMed ID: 9398294
    [Abstract] [Full Text] [Related]

  • 14. Evidence for two distinct Mg2+ binding sites in G(s alpha) and G(i alpha1) proteins.
    Malarkey CS, Wang G, Ballicora MA, Mota de Freitas DE.
    Biochem Biophys Res Commun; 2008 Aug 08; 372(4):866-9. PubMed ID: 18539137
    [Abstract] [Full Text] [Related]

  • 15. A novel mutation in the switch 3 region of Gsalpha in a patient with Albright hereditary osteodystrophy impairs GDP binding and receptor activation.
    Warner DR, Weng G, Yu S, Matalon R, Weinstein LS.
    J Biol Chem; 1998 Sep 11; 273(37):23976-83. PubMed ID: 9727013
    [Abstract] [Full Text] [Related]

  • 16. Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgammaS.
    Cherfils J, Ménétrey J, Le Bras G, Janoueix-Lerosey I, de Gunzburg J, Garel JR, Auzat I.
    EMBO J; 1997 Sep 15; 16(18):5582-91. PubMed ID: 9312017
    [Abstract] [Full Text] [Related]

  • 17. G protein amino-terminal alpha i2/alpha s chimeras reveal amino acids important in regulating alpha s activity.
    Russell M, Johnson GL.
    Mol Pharmacol; 1993 Aug 15; 44(2):255-63. PubMed ID: 8394989
    [Abstract] [Full Text] [Related]

  • 18. Identification of residues in the human guanylate-binding protein 1 critical for nucleotide binding and cooperative GTP hydrolysis.
    Praefcke GJ, Kloep S, Benscheid U, Lilie H, Prakash B, Herrmann C.
    J Mol Biol; 2004 Nov 12; 344(1):257-69. PubMed ID: 15504415
    [Abstract] [Full Text] [Related]

  • 19. The carboxyl terminus of the Galpha-subunit is the latch for triggered activation of heterotrimeric G proteins.
    Nanoff C, Koppensteiner R, Yang Q, Fuerst E, Ahorn H, Freissmuth M.
    Mol Pharmacol; 2006 Jan 12; 69(1):397-405. PubMed ID: 16210429
    [Abstract] [Full Text] [Related]

  • 20. Nucleotide-binding characteristics of human guanylate-binding protein 1 (hGBP1) and identification of the third GTP-binding motif.
    Praefcke GJ, Geyer M, Schwemmle M, Robert Kalbitzer H, Herrmann C.
    J Mol Biol; 1999 Sep 17; 292(2):321-32. PubMed ID: 10493878
    [Abstract] [Full Text] [Related]

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