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104 related items for PubMed ID: 1540653

  • 1. Interpretation of the roles of adenylosuccinate lyase and of AMP deaminase in the anti-HIV activity of 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine.
    Nair V, Sells TB.
    Biochim Biophys Acta; 1992 Feb 26; 1119(2):201-4. PubMed ID: 1540653
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  • 2. Enzymatic phosphorylation and pyrophosphorylation of 2',3'-dideoxyadenosine-5'-monophosphate, a key metabolite in the pathway for activation of the anti-HIV (human immunodeficiency virus) agent 2',3'-dideoxyinosine.
    Navé JF, Eschbach A, Wolff-Kugel D, Halazy S, Balzarini J.
    Biochem Pharmacol; 1994 Sep 15; 48(6):1105-12. PubMed ID: 7945403
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  • 3. Cellular phosphorylation of 2',3'-dideoxyadenosine-5'-monophosphate, a key intermediate in the activation of the antiviral agent DDI, in human peripheral blood mononuclear cells.
    Robbins BL, Greenhaw J, Fridland A.
    Nucleosides Nucleotides Nucleic Acids; 2000 Sep 15; 19(1-2):405-13. PubMed ID: 10772723
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  • 4. Intracellular activation of 2',3'-dideoxyinosine and drug interactions in vitro.
    Kewn S, Hoggard PG, Henry-Mowatt JS, Veal GJ, Sales SD, Barry MG, Back DJ.
    AIDS Res Hum Retroviruses; 1999 Jun 10; 15(9):793-802. PubMed ID: 10381167
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  • 5. Anomalous accumulation and decay of 2',3'-dideoxyadenosine-5'-triphosphate in human T-cell cultures exposed to the anti-HIV drug 2',3'-dideoxyinosine.
    Ahluwalia G, Cooney DA, Hartman NR, Mitsuya H, Yarchoan R, Fridland A, Broder S, Johns DG.
    Drug Metab Dispos; 1993 Jun 10; 21(2):369-76. PubMed ID: 8097711
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  • 6. Pharmacodynamic studies (PD) of didanosine (ddI) alone and in combination with azidothymidine (AZT) in human T-cells; a stochastic biochemical approach to antiretroviral nucleoside drug combination in inhibiting HIV-reverse transcriptase (RT).
    Periclou AP, Nandy P, Avramis VI.
    In Vivo; 2000 Jun 10; 14(3):377-88. PubMed ID: 10904870
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  • 7. cycloSal-Pronucleotides of 2',3'-dideoxyadenosine and 2', 3'-dideoxy-2',3'-didehydroadenosine: synthesis and antiviral evaluation of a highly efficient nucleotide delivery system.
    Meier C, Knispel T, De Clercq E, Balzarini J.
    J Med Chem; 1999 May 06; 42(9):1604-14. PubMed ID: 10229629
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  • 13. Role of altered metabolism in dideoxynucleoside pharmacokinetics. Studies of 2'-beta-fluoro-2',3'-dideoxyinosine and 2'-beta-fluoro-2',3'-dideoxyadenosine in rats.
    Singhal D, Morgan ME, Anderson BD.
    Drug Metab Dispos; 1996 Oct 06; 24(10):1155-61. PubMed ID: 8894519
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  • 14. Role of brain tissue localized purine metabolizing enzymes in the central nervous system delivery of anti-HIV agents 2'-beta-fluoro-2',3'-dideoxyinosine and 2'-beta-fluoro-2',3'-dideoxyadenosine in rats.
    Singhal D, Morgan ME, Anderson BD.
    Pharm Res; 1997 Jun 06; 14(6):786-92. PubMed ID: 9210198
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  • 15. Uptake and distribution of 2',3'-dideoxyinosine and its derivatives in a human monocytoid cell line.
    Vázquez-Padua MA, Mayol N, López M.
    Cell Mol Biol (Noisy-le-grand); 1995 Jun 06; 41 Suppl 1():S113-9. PubMed ID: 8574139
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  • 16. Enzymes of the purine nucleotide cycle in muscle of patients with exercise intolerance.
    Operti MG, Vincent MF, Brucher JM, van den Berghe G.
    Muscle Nerve; 1998 Mar 06; 21(3):401-3. PubMed ID: 9486871
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  • 17. Enhancement by 2'-deoxycoformycin of the 5'-phosphorylation and anti-human immunodeficiency virus activity of 2',3'-dideoxyadenosine and 2'-beta-fluoro-2',3'-dideoxyadenosine.
    Ahluwalia GS, Cooney DA, Shirasaka T, Mitsuya H, Driscoll JS, Johns DG.
    Mol Pharmacol; 1994 Nov 06; 46(5):1002-8. PubMed ID: 7969062
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  • 18. Enzymatic properties of the unnatural beta-L-enantiomers of 2',3'-dideoxyadenosine and 2',3'-didehydro-2',3'-dideoxyadenosine.
    Pélicano H, Pierra C, Eriksson S, Gosselin G, Imbach JL, Maury G.
    J Med Chem; 1997 Nov 21; 40(24):3969-73. PubMed ID: 9397178
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  • 19. In vitro and in vivo evaluation of 6-azido-2',3'-dideoxy-2'-fluoro-beta-D-arabinofuranosylpurine and N6-methyl-2',3'-dideoxy-2'-fluoro-beta-D-arabinofuranosyladenine as prodrugs of the anti-HIV nucleosides 2'-F-ara-ddA and 2'-F-ara-ddI.
    Koudriakova T, Manouilov KK, Shanmuganathan K, Kotra LP, Boudinot FD, Cretton-Scott E, Sommadossi JP, Schinazi RF, Chu CK.
    J Med Chem; 1996 Nov 08; 39(23):4676-81. PubMed ID: 8917656
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  • 20. Simultaneous determination of 2',3'-dideoxyinosine and the active metabolite, 2',3'-dideoxyadenosine-5'-triphosphate in human peripheral-blood mononuclear cell by HPLC-MS/MS and the application to cell pharmacokinetics.
    Lan X, Mingdao L, Huilin G, Wei G, Lvjiang H, Yan Z, Gang L.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2015 Oct 01; 1002():337-42. PubMed ID: 26350426
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