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Journal Abstract Search

311 related items for PubMed ID: 1544541

  • 21. Modulation of mammalian O6-alkylguanine-DNA alkyltransferase in vivo by O6-benzylguanine and its effect on the sensitivity of a human glioma tumor to 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea.
    Dolan ME, Stine L, Mitchell RB, Moschel RC, Pegg AE.
    Cancer Commun; 1990; 2(11):371-7. PubMed ID: 2242301
    [Abstract] [Full Text] [Related]

  • 22. Depletion of O6-alkylguanine-DNA alkyltransferase by O6-benzylguanine in three-dimensional collagen cultures of normal human breast epithelial cells.
    Hamdan MA, Guzman RC, Yang J, Beattie C, Mascharack P, Nandi S.
    Carcinogenesis; 1992 Oct; 13(10):1743-9. PubMed ID: 1423833
    [Abstract] [Full Text] [Related]

  • 23. Repair of O(6)-alkylguanine by alkyltransferases.
    Pegg AE.
    Mutat Res; 2000 Apr; 462(2-3):83-100. PubMed ID: 10767620
    [Abstract] [Full Text] [Related]

  • 24. Effect of O6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents.
    Dolan ME, Mitchell RB, Mummert C, Moschel RC, Pegg AE.
    Cancer Res; 1991 Jul 01; 51(13):3367-72. PubMed ID: 1647266
    [Abstract] [Full Text] [Related]

  • 25. Mutations in human O6-alkylguanine-DNA alkyltransferase imparting resistance to O6-benzylguanine.
    Crone TM, Goodtzova K, Edara S, Pegg AE.
    Cancer Res; 1994 Dec 01; 54(23):6221-7. PubMed ID: 7954470
    [Abstract] [Full Text] [Related]

  • 26. Repair of O6-alkylguanine during DNA synthesis in murine bone marrow hematopoietic precursors.
    Gerson SL, Trey JE, Miller K, Benjamin E.
    Cancer Res; 1987 Jan 01; 47(1):89-95. PubMed ID: 3539320
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  • 27. O6-alkylguanine-DNA alkyltransferase. A target for the modulation of drug resistance.
    Gerson SL, Willson JK.
    Hematol Oncol Clin North Am; 1995 Apr 01; 9(2):431-50. PubMed ID: 7642472
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  • 28. A novel, sensitive assay for O6-methyl- and O6-ethylguanine in DNA, based on repair by the enzyme O6-alkylguanine-DNA-alkyltransferase in competition with an oligonucleotide containing O6-methylguanine.
    Souliotis VL, Kyrtopoulos SA.
    Cancer Res; 1989 Dec 15; 49(24 Pt 1):6997-7001. PubMed ID: 2684406
    [Abstract] [Full Text] [Related]

  • 29. Investigation of the role of tyrosine-114 in the activity of human O6-alkylguanine-DNA alkyltranferase.
    Goodtzova K, Kanugula S, Edara S, Pegg AE.
    Biochemistry; 1998 Sep 08; 37(36):12489-95. PubMed ID: 9730821
    [Abstract] [Full Text] [Related]

  • 30. O6-Alkylguanine-DNA alkyltransferase: influence on susceptibility to the genetic effects of alkylating agents.
    Kyrtopoulos SA.
    Toxicol Lett; 1998 Dec 28; 102-103():53-7. PubMed ID: 10022232
    [Abstract] [Full Text] [Related]

  • 31. The repair of the tobacco specific nitrosamine derived adduct O6-[4-Oxo-4-(3-pyridyl)butyl]guanine by O6-alkylguanine-DNA alkyltransferase variants.
    Mijal RS, Thomson NM, Fleischer NL, Pauly GT, Moschel RC, Kanugula S, Fang Q, Pegg AE, Peterson LA.
    Chem Res Toxicol; 2004 Mar 28; 17(3):424-34. PubMed ID: 15025514
    [Abstract] [Full Text] [Related]

  • 32. Specific labeling of O6-alkylguanine-DNA alkyltransferase by reaction with O6-(p-hydroxy[3H]methylbenzyl)guanine.
    Ciocco GM, Moschel RC, Chae MY, McLaughlin PJ, Zagon IS, Pegg AE.
    Cancer Res; 1995 Sep 15; 55(18):4085-91. PubMed ID: 7664284
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  • 35. Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea.
    Liu L, Markowitz S, Gerson SL.
    Cancer Res; 1996 Dec 01; 56(23):5375-9. PubMed ID: 8968088
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  • 37. Conformational change in human DNA repair enzyme O6-methylguanine-DNA methyltransferase upon alkylation of its active site by SN1 (indirect-acting) and SN2 (direct-acting) alkylating agents: breaking a "salt-link".
    Oh HK, Teo AK, Ali RB, Lim A, Ayi TC, Yarosh DB, Li BF.
    Biochemistry; 1996 Sep 24; 35(38):12259-66. PubMed ID: 8823159
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  • 39. Role of DNA repair in resistance to drugs that alkylate O6 of guanine.
    Koç ON, Phillips WP, Lee K, Liu L, Zaidi NH, Allay JA, Gerson SL.
    Cancer Treat Res; 1996 Sep 24; 87():123-46. PubMed ID: 8886451
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