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239 related items for PubMed ID: 15450084

  • 1. 12-Lipoxygenase plays a key role in cell death caused by glutathione depletion and arachidonic acid in rat oligodendrocytes.
    Wang H, Li J, Follett PL, Zhang Y, Cotanche DA, Jensen FE, Volpe JJ, Rosenberg PA.
    Eur J Neurosci; 2004 Oct; 20(8):2049-58. PubMed ID: 15450084
    [Abstract] [Full Text] [Related]

  • 2. Developmental up-regulation of MnSOD in rat oligodendrocytes confers protection against oxidative injury.
    Baud O, Haynes RF, Wang H, Folkerth RD, Li J, Volpe JJ, Rosenberg PA.
    Eur J Neurosci; 2004 Jul; 20(1):29-40. PubMed ID: 15245476
    [Abstract] [Full Text] [Related]

  • 3. Apoptosis of W256 carcinosarcoma cells of the monocytoid origin induced by NDGA involves lipid peroxidation and depletion of GSH: role of 12-lipoxygenase in regulating tumor cell survival.
    Tang DG, Honn KV.
    J Cell Physiol; 1997 Aug; 172(2):155-70. PubMed ID: 9258337
    [Abstract] [Full Text] [Related]

  • 4. Vitamin K prevents oxidative cell death by inhibiting activation of 12-lipoxygenase in developing oligodendrocytes.
    Li J, Wang H, Rosenberg PA.
    J Neurosci Res; 2009 Jul; 87(9):1997-2005. PubMed ID: 19235890
    [Abstract] [Full Text] [Related]

  • 5. Arachidonic acid converts the glutathione depletion-induced apoptosis to necrosis by promoting lipid peroxidation and reducing caspase-3 activity in rat glioma cells.
    Higuchi Y, Yoshimoto T.
    Arch Biochem Biophys; 2002 Apr 01; 400(1):133-40. PubMed ID: 11913980
    [Abstract] [Full Text] [Related]

  • 6. Arachidonic acid promotes glutamate-induced cell death associated with necrosis by 12- lipoxygenase activation in glioma cells.
    Higuchi Y, Tanii H, Koriyama Y, Mizukami Y, Yoshimoto T.
    Life Sci; 2007 Apr 24; 80(20):1856-64. PubMed ID: 17400255
    [Abstract] [Full Text] [Related]

  • 7. Arachidonic acid induces neuronal death through lipoxygenase and cytochrome P450 rather than cyclooxygenase.
    Kwon KJ, Jung YS, Lee SH, Moon CH, Baik EJ.
    J Neurosci Res; 2005 Jul 01; 81(1):73-84. PubMed ID: 15931672
    [Abstract] [Full Text] [Related]

  • 8. 5-Lipoxygenase inhibitors attenuate growth of human renal cell carcinoma and induce apoptosis through arachidonic acid pathway.
    Matsuyama M, Yoshimura R, Mitsuhashi M, Tsuchida K, Takemoto Y, Kawahito Y, Sano H, Nakatani T.
    Oncol Rep; 2005 Jul 01; 14(1):73-9. PubMed ID: 15944770
    [Abstract] [Full Text] [Related]

  • 9. Maturation-dependent vulnerability of oligodendrocytes to oxidative stress-induced death caused by glutathione depletion.
    Back SA, Gan X, Li Y, Rosenberg PA, Volpe JJ.
    J Neurosci; 1998 Aug 15; 18(16):6241-53. PubMed ID: 9698317
    [Abstract] [Full Text] [Related]

  • 10. Lipoxygenase inhibitors abolish proliferation of human pancreatic cancer cells.
    Ding XZ, Iversen P, Cluck MW, Knezetic JA, Adrian TE.
    Biochem Biophys Res Commun; 1999 Jul 22; 261(1):218-23. PubMed ID: 10405349
    [Abstract] [Full Text] [Related]

  • 11. Ceramide elevates 12-hydroxyeicosatetraenoic acid levels and upregulates 12-lipoxygenase in rat primary hippocampal cell cultures containing predominantly astrocytes.
    Prasad VV, Nithipatikom K, Harder DR.
    Neurochem Int; 2008 Dec 22; 53(6-8):220-9. PubMed ID: 18680775
    [Abstract] [Full Text] [Related]

  • 12. Distinct role of nitric oxide and peroxynitrite in mediating oligodendrocyte toxicity in culture and in experimental autoimmune encephalomyelitis.
    Li S, Vana AC, Ribeiro R, Zhang Y.
    Neuroscience; 2011 Jun 16; 184():107-19. PubMed ID: 21511012
    [Abstract] [Full Text] [Related]

  • 13. Activation of 5-lipoxygenase after oxygen-glucose deprivation is partly mediated via NMDA receptor in rat cortical neurons.
    Ge QF, Wei EQ, Zhang WP, Hu X, Huang XJ, Zhang L, Song Y, Ma ZQ, Chen Z, Luo JH.
    J Neurochem; 2006 May 16; 97(4):992-1004. PubMed ID: 16606359
    [Abstract] [Full Text] [Related]

  • 14. Depletion of intracellular glutathione mediates butenolide-induced cytotoxicity in HepG2 cells.
    Wang YM, Peng SQ, Zhou Q, Wang MW, Yan CH, Yang HY, Wang GQ.
    Toxicol Lett; 2006 Jul 14; 164(3):231-8. PubMed ID: 16495022
    [Abstract] [Full Text] [Related]

  • 15. Antitumor effects of lipoxygenase inhibitors on murine bladder cancer cell line (MBT-2).
    Ikemoto S, Sugimura K, Kuratukuri K, Nakatani T.
    Anticancer Res; 2004 Jul 14; 24(2B):733-6. PubMed ID: 15161019
    [Abstract] [Full Text] [Related]

  • 16. Estradiol attenuates hyperoxia-induced cell death in the developing white matter.
    Gerstner B, Sifringer M, Dzietko M, Schüller A, Lee J, Simons S, Obladen M, Volpe JJ, Rosenberg PA, Felderhoff-Mueser U.
    Ann Neurol; 2007 Jun 14; 61(6):562-73. PubMed ID: 17427919
    [Abstract] [Full Text] [Related]

  • 17. Nordihydroguaiaretic acid induces astroglial death via glutathione depletion.
    Im JY, Han PL.
    J Neurosci Res; 2007 Nov 01; 85(14):3127-34. PubMed ID: 17663482
    [Abstract] [Full Text] [Related]

  • 18. 12/15-lipoxygenase expression is increased in oligodendrocytes and microglia of periventricular leukomalacia.
    Haynes RL, van Leyen K.
    Dev Neurosci; 2013 Nov 01; 35(2-3):140-54. PubMed ID: 23838566
    [Abstract] [Full Text] [Related]

  • 19. Hyperoxia causes maturation-dependent cell death in the developing white matter.
    Gerstner B, DeSilva TM, Genz K, Armstrong A, Brehmer F, Neve RL, Felderhoff-Mueser U, Volpe JJ, Rosenberg PA.
    J Neurosci; 2008 Jan 30; 28(5):1236-45. PubMed ID: 18234901
    [Abstract] [Full Text] [Related]

  • 20. Licofelone, a dual COX/5-LOX inhibitor, induces apoptosis in HCA-7 colon cancer cells through the mitochondrial pathway independently from its ability to affect the arachidonic acid cascade.
    Tavolari S, Bonafè M, Marini M, Ferreri C, Bartolini G, Brighenti E, Manara S, Tomasi V, Laufer S, Guarnieri T.
    Carcinogenesis; 2008 Feb 30; 29(2):371-80. PubMed ID: 18033773
    [Abstract] [Full Text] [Related]


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