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Journal Abstract Search

277 related items for PubMed ID: 15451401

  • 1. GABA(A) agonists and partial agonists: THIP (Gaboxadol) as a non-opioid analgesic and a novel type of hypnotic.
    Krogsgaard-Larsen P, Frølund B, Liljefors T, Ebert B.
    Biochem Pharmacol; 2004 Oct 15; 68(8):1573-80. PubMed ID: 15451401
    [Abstract] [Full Text] [Related]

  • 2. Specific GABA(A) agonists and partial agonists.
    Krogsgaard-Larsen P, Frølund B, Liljefors T.
    Chem Rec; 2002 Oct 15; 2(6):419-30. PubMed ID: 12469353
    [Abstract] [Full Text] [Related]

  • 3. GABA(A) receptor ligands and their therapeutic potentials.
    Frølund B, Ebert B, Kristiansen U, Liljefors T, Krogsgaard-Larsen P.
    Curr Top Med Chem; 2002 Aug 15; 2(8):817-32. PubMed ID: 12171573
    [Abstract] [Full Text] [Related]

  • 4. The EEG effects of THIP (Gaboxadol) on sleep and waking are mediated by the GABA(A)delta-subunit-containing receptors.
    Winsky-Sommerer R, Vyazovskiy VV, Homanics GE, Tobler I.
    Eur J Neurosci; 2007 Mar 15; 25(6):1893-9. PubMed ID: 17408425
    [Abstract] [Full Text] [Related]

  • 5. Pharmacological characterization of agonists at delta-containing GABAA receptors: Functional selectivity for extrasynaptic receptors is dependent on the absence of gamma2.
    Stórustovu SI, Ebert B.
    J Pharmacol Exp Ther; 2006 Mar 15; 316(3):1351-9. PubMed ID: 16272218
    [Abstract] [Full Text] [Related]

  • 6. Modulation of extrasynaptic THIP conductances by GABAA-receptor modulators in mouse neocortex.
    Drasbek KR, Hoestgaard-Jensen K, Jensen K.
    J Neurophysiol; 2007 Mar 15; 97(3):2293-300. PubMed ID: 17215511
    [Abstract] [Full Text] [Related]

  • 7. An extrasynaptic GABAA receptor mediates tonic inhibition in thalamic VB neurons.
    Jia F, Pignataro L, Schofield CM, Yue M, Harrison NL, Goldstein PA.
    J Neurophysiol; 2005 Dec 15; 94(6):4491-501. PubMed ID: 16162835
    [Abstract] [Full Text] [Related]

  • 8. Extrasynaptic GABAA receptors are critical targets for sedative-hypnotic drugs.
    Orser BA.
    J Clin Sleep Med; 2006 Apr 15; 2(2):S12-8. PubMed ID: 17557502
    [Abstract] [Full Text] [Related]

  • 9. Gaboxadol--a new awakening in sleep.
    Wafford KA, Ebert B.
    Curr Opin Pharmacol; 2006 Feb 15; 6(1):30-6. PubMed ID: 16368265
    [Abstract] [Full Text] [Related]

  • 10. Differences in agonist/antagonist binding affinity and receptor transduction using recombinant human gamma-aminobutyric acid type A receptors.
    Ebert B, Thompson SA, Saounatsou K, McKernan R, Krogsgaard-Larsen P, Wafford KA.
    Mol Pharmacol; 1997 Dec 15; 52(6):1150-6. PubMed ID: 9396785
    [Abstract] [Full Text] [Related]

  • 11. Mechanisms of sleep induction by GABA(A) receptor agonists.
    Harrison NL.
    J Clin Psychiatry; 2007 Dec 15; 68 Suppl 5():6-12. PubMed ID: 17539703
    [Abstract] [Full Text] [Related]

  • 12. delta-Subunit containing GABAA receptor knockout mice are less sensitive to the actions of 4,5,6,7-tetrahydroisoxazolo-[5,4-c]pyridin-3-ol.
    Boehm SL, Homanics GE, Blednov YA, Harris RA.
    Eur J Pharmacol; 2006 Jul 17; 541(3):158-62. PubMed ID: 16777089
    [Abstract] [Full Text] [Related]

  • 13. Gaboxadol -- a different hypnotic profile with no tolerance to sleep EEG and sedative effects after repeated daily dosing.
    Ebert B, Anderson NJ, Cremers TI, Rasmussen S, Vogel V, Fahey JM, Sánchez C.
    Pharmacol Biochem Behav; 2008 Jul 17; 90(1):113-22. PubMed ID: 18304623
    [Abstract] [Full Text] [Related]

  • 14. Potent 4-aryl- or 4-arylalkyl-substituted 3-isoxazolol GABA(A) antagonists: synthesis, pharmacology, and molecular modeling.
    Frølund B, Jensen LS, Guandalini L, Canillo C, Vestergaard HT, Kristiansen U, Nielsen B, Stensbøl TB, Madsen C, Krogsgaard-Larsen P, Liljefors T.
    J Med Chem; 2005 Jan 27; 48(2):427-39. PubMed ID: 15658856
    [Abstract] [Full Text] [Related]

  • 15. Centrally-mediated antinociceptive actions of GABA(A) receptor agonists in the rat spared nerve injury model of neuropathic pain.
    Rode F, Jensen DG, Blackburn-Munro G, Bjerrum OJ.
    Eur J Pharmacol; 2005 Jun 01; 516(2):131-8. PubMed ID: 15936014
    [Abstract] [Full Text] [Related]

  • 16. Characterization of GABA(A) receptor ligands in the rat cortical wedge preparation: evidence for action at extrasynaptic receptors?
    Ebert B, i Storustovu S, Mortensen M, Frølund B.
    Br J Pharmacol; 2002 Sep 01; 137(1):1-8. PubMed ID: 12183325
    [Abstract] [Full Text] [Related]

  • 17. Altered pharmacology of synaptic and extrasynaptic GABAA receptors on CA1 hippocampal neurons is consistent with subunit changes in a model of alcohol withdrawal and dependence.
    Liang J, Cagetti E, Olsen RW, Spigelman I.
    J Pharmacol Exp Ther; 2004 Sep 01; 310(3):1234-45. PubMed ID: 15126642
    [Abstract] [Full Text] [Related]

  • 18. Effects of GABA(A) receptor partial agonists in primary cultures of cerebellar granule neurons and cerebral cortical neurons reflect different receptor subunit compositions.
    Hansen SL, Ebert B, Fjalland B, Kristiansen U.
    Br J Pharmacol; 2001 Jun 01; 133(4):539-49. PubMed ID: 11399671
    [Abstract] [Full Text] [Related]

  • 19. gamma-aminobutyric Acid(A) (GABA(A)) agonist 4,5,6, 7-tetrahydroisoxazolo[4,5-c]pyridin-3-ol persistently increases sleep maintenance and intensity during chronic administration to rats.
    Lancel M, Langebartels A.
    J Pharmacol Exp Ther; 2000 Jun 01; 293(3):1084-90. PubMed ID: 10869413
    [Abstract] [Full Text] [Related]

  • 20. Treating insomnia: Current and investigational pharmacological approaches.
    Ebert B, Wafford KA, Deacon S.
    Pharmacol Ther; 2006 Dec 01; 112(3):612-29. PubMed ID: 16876255
    [Abstract] [Full Text] [Related]

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